Wnt-signaling pathway
The Wnt Signaling Pathway Is Differentially Expressed during the Bovine Herpesvirus 1 Latency-Reactivation Cycle: Evidence That Two Protein Kinases Associated with Neuronal Survival, Akt3 and BMPR2, Are Expressed at Higher Levels during Latency
... (NGF) signaling is active (55, ...Akt signaling stimulated the Wnt/  -catenin signal- ing pathway by directly phosphorylating  -catenin on serine 552 and increasing  -catenin-dependent ...
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Original Article Pathway analysis of esophageal squamous cell carcinoma using iTRAQ-based quantitative proteomic approach
... that Wnt signaling pathway played a very important role in the development of ...(KEGG) pathway database were matched against by those proteins’ ...and signaling pathways could help ...
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Integrated omics-analysis reveals Wnt-mediated NAD metabolic reprogramming in cancer stem-like cells
... the Wnt signaling pathway and its expression is modulated by Wnt activity [26, ...the Wnt pathway is not clearly ...elucidated. Wnt, of note, has been reported to be ...
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De novo transcriptomic analysis of the female and male adults of the blood fluke Schistosoma turkestanicum
... as Wnt signaling pathway (103; 2 %). The Wnt signaling pathway is a conserved signaling net- work, which takes part in embryonic development, cell differentiation and ...
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A Genome-Wide RNA Interference Screen Identifies a Role for Wnt/β-Catenin Signaling during Rift Valley Fever Virus Infection
... Panther pathway classi- fication system ...the Wnt signaling pathway was the most represented pathway with 9% (8 of 89) of the genes ...the Wnt pathway was among the most ...
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Original Article TRAF4 enhances oral squamous cell carcinoma cell growth, invasion and migration by Wnt-β-catenin signaling pathway
... Wnt/β-catenin pathway ranks as the best understood Wnt signaling pathway and is highly conserved during ...that Wnt/β-catenin pathway possesses multiple roles in ...
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Developments in the scientific understanding of osteoporosis
... The Wnt signaling pathway is well known in developmental biology and growth, and metastases of cancer, but the connection to the skeleton was not initially clear ...the Wnt signaling ...
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Original Article Association of AXIN2 and MMP7 polymorphisms with non-small cell lung cancer in Chinese Han population
... the Wnt signaling pathway in stably ...that Wnt/β-catenin pa- thway influences the development of cancer through activating the downstream target ge- nes mainly ...the Wnt ...
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Activation of the basal cell carcinoma pathway in a patient with CNS HGNET-BCOR diagnosis: consequences for personalized targeted therapy
... Ingenuity Pathway Analysis, we identified the activation of the Sonic Hedgehog (SHH) and of the WNT signaling pathway in two different regions of the primary tumor and of one inoculation ...
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Long non coding RNAs regulate Wnt signaling during feather regeneration
... modules, Wnt signaling is of particular interest not only because it is involved in the regeneration of many organs, but also because genes in this pathway showed distinct dynamic expression patterns ...
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Flamingo, a cadherin type receptor involved in the Drosophila planar polarity pathway, can block signaling via the canonical wnt pathway in Xenopus laevis
... the wnt signaling pathway is actual involved (apart from Fz and Dsh ), including the wnt ligand itself (reviewed by Adler and Lee, ...that wnt signaling also regulates these cell ...
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Original Article Wnt/beta-catenin signaling pathway regulates beta1,4-galactosyltransferase l expression in the endometrium to affect the embryo implantation
... canonical Wnt signaling pathway, which is a key molecule in the whole ...canonical Wnt signaling pathway but also plays an important role in mediating cell and cell adhesion [9, ...
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FH535 increases the radiosensitivity and reverses epithelial to mesenchymal transition of radioresistant esophageal cancer cell line KYSE 150R
... intracellular signaling. The canonical Wnt pathway stabilizes β-catenin and activates target genes via TCF/Lef transcription ...and Wnt/β-catenin signaling pathway, might be a ...
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High Plasma Concentrations of Sclerostin, an Inhibitor of the Wnt Signaling Pathway, in Young Horses Affected by Osteochondrosis
... canonical Wnt /β -catenin signaling by binding to Wnt co-receptors, low-density lipoprotein receptor-related protein 4, 5 and 6 [8] (Figure ...
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Grape compounds suppress colon cancer stem cells in vitro and in a rodent model of colon carcinogenesis
... of Wnt/β-catenin pathway, c-Myc and cyclin D1 ...of Wnt signaling and both function in the stimulation of cell proliferation and in preventing ...
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Overexpression of Klotho suppresses liver cancer progression and induces cell apoptosis by negatively regulating wnt/β catenin signaling pathway
... Next, we wanted to know whether overexpression of Klotho would affect the translocation of β-catenin. Thus, we detected the distribution of β-catenin in cytoplasm and the nucleus. As shown in Fig. 6, in ...
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Original Article Knockdown of CUL4B inhibits proliferation and promotes apoptosis of colorectal cancer cells through suppressing the Wnt/β-catenin signaling pathway
... Abstract: Colorectal cancer is one of the leading causes of cancer related deaths worldwide. Cullin 4B (CUL4B) is over-expressed in diverse cancer types. However, the function and precise molecular mechanism of CUL4B in ...
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The polarity protein VANG 1 antagonizes Wnt signaling by facilitating Frizzled endocytosis
... for Wnt, Dishevelled and β -catenin, respectively, and are required for the posterior migration of ...antagonizes Wnt signaling specifically at the level of Frizzled ...of Wnt ligand (egl-20) ...
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Semaphorin 3d promotes cell proliferation and neural crest cell development downstream of TCF in the zebrafish hindbrain
... Sema4d-mediated growth cone collapse (Ito et al., 2006). The two pathways also share the ability to affect both the cell cycle and cell adhesions, and thus there are multiple points where the pathways might converge. For ...
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Original Article Topical application of 8DSS induces anagen hair growth in telogenic mouse skin
... pressed Wnt ligand in hair follicle development and hair cycle induction and is expressed in hair follicles in postnatal skin ...the Wnt/β-catenin signaling pathway is essen- tial in ...
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