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X chromosome

Nonrandom X Chromosome Inactivation Is Influenced by Multiple Regions on the Murine X Chromosome

Nonrandom X Chromosome Inactivation Is Influenced by Multiple Regions on the Murine X Chromosome

... using X chromosome microsatellite markers and SNPs listed in Table S1 and Table ...the X chromosome with DXMit53, DXMit62, DXMit18, DXMit64, and DXMit249 map pairs and then fine mapped recombi- ...

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A skewed view of X chromosome inactivation

A skewed view of X chromosome inactivation

... parental X active. While in most females the number of cells with either X being active is roughly equal, skewing of X chromosome inactivation is observed in a percentage of ...of X ...

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Pgk1 and Hprt gene activity in the peri implantation mouse embryo is influenced by the parental origin of the X chromosome

Pgk1 and Hprt gene activity in the peri implantation mouse embryo is influenced by the parental origin of the X chromosome

... both X chromosomes are transcriptionally ...two X-linked genes, Pgk1 and Hprt, reveals that the amount of transcript (mRNA copies per embryo) encoded by the alleles on the maternally derived X- ...

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Demasculinization of the Anopheles gambiae X chromosome

Demasculinization of the Anopheles gambiae X chromosome

... which X- linkage is associated with a high degree of loss of male- ...male, X-linkage is not asso- ciated with an increased expression divergence in the fe- ...Anopheles X chromosome is not ...

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Physical mapping of the human X chromosome

Physical mapping of the human X chromosome

... the X chromosome retrieved 1,723 ...the chromosome were often relative to a cytogenetic band and not to neighbouring loci, which is not sufficient for placing clones on a ...on X ...

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X chromosome inactivation in the cycle of life

X chromosome inactivation in the cycle of life

... equalize X-encoded gene expression, female somatic cells transcriptionally silence one of the two X chromosomes in a process named X chromosome inactivation (XCI), which leads to mono-allelic ...

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Skewed X-chromosome inactivation in scleroderma.

Skewed X-chromosome inactivation in scleroderma.

... DNA samples were obtained from 195 scleroderma patients and 160 control women. Clinical characteristics of the patients and controls have been published elsewhere. (12,13) The ethics review boards at the participating ...

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Mammalian X chromosome inactivation evolved as a dosage compensation mechanism for dosage sensitive genes on the X chromosome

Mammalian X chromosome inactivation evolved as a dosage compensation mechanism for dosage sensitive genes on the X chromosome

... of X-linked genes in both sexes [Ohno S (1967) (Springer, ...of X chromosome expres- sion between the sexes has been clearly demonstrated, tests for the doubling of expression levels globally along ...

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Chromosome silencing mechanisms in X chromosome inactivation: unknown unknowns

Chromosome silencing mechanisms in X chromosome inactivation: unknown unknowns

... for X-chromosome silencing When Xist first appeared on the scene, the field discussed two competing models for Xist-mediated chromosome silencing: first, that Xist produces a functional non-coding ...

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The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence

The X chromosome of the German cockroach, Blattella germanica, is homologous to a fly X chromosome despite 400 million years divergence

... identify X chromosome genes in the German cock- roach genome assembly. X-linked genes are expected to have half as many male-derived reads mapped to them as female-derived reads because the X ...

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A Genealogical Look at Shared Ancestry on the X Chromosome

A Genealogical Look at Shared Ancestry on the X Chromosome

... of X genetic ancestry. Then, in the X Ancestry section we look at X genealogies, as their properties affect the transmission of X genetic material from X ancestors to a present-day ...

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X chromosome aneuploidy in the Alzheimer’s disease brain

X chromosome aneuploidy in the Alzheimer’s disease brain

... Since X chromo- some loss is one of the most prominent hallmarks of aging in human females [21] and an association between aging and aneuploidy in the murine brain has been shown [22], it is attractive to test ...

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Gender  and gamete specific patterns of X chromosome segregation in a three gendered nematode

Gender and gamete specific patterns of X chromosome segregation in a three gendered nematode

... the X chromosomes segregate to the pole fated to become functional ...the X chromosome is inherited through the sperm-producing germline and from father to son in the event of a ...complete X ...

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Sex-Biased Gene Expression and Evolution of the X Chromosome in Nematodes

Sex-Biased Gene Expression and Evolution of the X Chromosome in Nematodes

... the X chromosome and the autosomes (Saifi and Chandra 1999; Wang et ...the X. Enrichment of female-biased genes on the X chromosome (“feminization of the X”) is observed in ...

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Low RNA Binding Strength of Human X Chromosome May Explain X Chromosome Inactivation

Low RNA Binding Strength of Human X Chromosome May Explain X Chromosome Inactivation

... Two X chromosomes of female mammals randomly inactivate one of paternal or maternal X chromosome in early embryonic development and all the daughter cells produced from these cells retain the same ...

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Complex X chromosome rearrangement associated with multiorgan autoimmunity

Complex X chromosome rearrangement associated with multiorgan autoimmunity

... complex X chromosome rearrangement in a young female patient presenting successively a wide range of autoimmune diseases including insulin dependent diabetes mellitus, Hashimoto ’ s thyroiditis, celiac ...

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Mechanics and dynamics of X chromosome pairing at X inactivation

Mechanics and dynamics of X chromosome pairing at X inactivation

... for X chromosome colocaliza- tion at XCI in the Tsix/Xite ...that X colocalization can be spontaneously attained only when the concentration, or affinity, of molecules is above a critical ...

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X Chromosome Evolution in Cetartiodactyla

X Chromosome Evolution in Cetartiodactyla

... Ancestral X (CAX). We confirmed the conservation of the X chromosome in basal branches of ...uniform X chromosome morphology and banding pattern ...Hippopotamidae X ...

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Recombination between small X chromosome duplications and the X chromosome in Caenorhabditis elegans.

Recombination between small X chromosome duplications and the X chromosome in Caenorhabditis elegans.

... hermaphrodites carrying either duplication (Figure 2), and the frequency of nullo-duplication self progeny from duplication-bearing hermaphrodites was in each case greater[r] ...

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X chromosome duplications affect a region of the chromosome they do not duplicate in Caenorhabditis elegans.

X chromosome duplications affect a region of the chromosome they do not duplicate in Caenorhabditis elegans.

... We show here that duplications suppress an X-linked hypomorphic mutation and elevate the level of activity of an X-linked enzyme, although these two genes are located in a re[r] ...

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