X chromosome dosage compensation
Diverse developmental strategies of X chromosome dosage compensation in eutherian mammals
... Imprinted X chromosome inactivation in rodents Imprinted X chromosome inactivation (iXCI) takes place in rodent preimplantation embryo and extraembryonic ...inherited X ...
12
Non-canonical Drosophila X chromosome dosage compensation and repressive topologically associated domains
... median X-linked gene expression level was ...the X-linked genes demonstrate gene expres- sion above the cutoff levels from LAD and Null domains, respectively (Table ...the X-linked genes were ...
18
Dual sex specific functions of Drosophila Upstream of N ras in the control of X chromosome dosage compensation
... male X chromosome, consisting of bloated or knotted ...influence X chromosome morphology, such as ISWI, NURF, JIL- 1 or SU(VAR)3-7 (Deng et ...bloated X chromosome and depletion ...
10
Assessment of X Chromosome Dosage Compensation in Caenorhabditis elegans by Phenotypic Analysis of lin-14
... Quantitation by densitometry of five similar experiments indicates that the extent of overexpression is 1.9-fold (standard error of the mean is 0.01). The lin-I 4 assa[r] ...
14
A Role for siRNA in X-Chromosome Dosage Compensation in Drosophila melanogaster
... (E) Percentage of nuclei with minimal or no MSL1 recruit- ment to the X chromosome (sum of categories “+” and “no MSL recruitment,” Table S1A). (F) Ec- topic autosomal MSL1 binding in a roX1 ex40 roX2 Δ; ...
10
Genetic Analysis of X-Chromosome Dosage Compensation in Caenorhabditis elegans
... 1 2X pseudomales in C. Like the presence of a third X chromosome in 2A:3X animals, recessive mutations in dpy-21 and dpy-26 specifically suppress the phenotypes of X-linked hypomorph[r] ...
17
Untangling the Contributions of Sex-Specific Gene Regulation and X-Chromosome Dosage to Sex-Biased Gene Expression in Caenorhabditis elegans
... ABSTRACT Dosage compensation mechanisms equalize the level of X chromosome expression between ...the X chromosome is often enriched for genes exhibiting sex-biased, ...between ...
22
The Caenorhabditis elegans Dosage Compensation Machinery Is Recruited to X Chromosome DNA Attached to an Autosome
... The dosage compensation machinery of Caenorhabditis elegans is targeted specifically to the X chromo- somes of hermaphrodites (XX) to reduce gene expression by ...the dosage ...
19
Mammalian X chromosome inactivation evolved as a dosage compensation mechanism for dosage sensitive genes on the X chromosome
... be dosage-sensitive and should be the main target for dosage ...both X and autosomal genes. We computed the X/A expression ratio within each complex and we obtained the median of this ratio ...
12
Evolution of Dosage Compensation in Diptera: The Gene maleless Implements Dosage Compensation in Drosophila (Brachycera Suborder) but Its Homolog in Sciara (Nematocera Suborder) Appears to Play No Role in Dosage Compensation
... male X chromosome of ...the X chromosome, which MSL1 proteins are not specifically located in the male showed a heavily banded appearance, while the au- X chromosome, as in ...
14
Dosage compensation of the Drosophila white gene requires both the X chromosome environment and multiple intragenic elements.
... When inserted in ectopic X chromosome sites, the mini-white gene of the CaspeR vector can be fully dosage compensated and can even achieve hyperdosage compensation,[r] ...
12
Extreme heterogeneity in sex chromosome differentiation and dosage compensation in livebearers
... sex chromosome divergence began independently in ...Y chromosome in ...Y chromosome or an X0 ...Y chromosome is indeed ...the X is half that of females, consistent with large-scale loss ...
7
Transcriptional effects of gene dose reduction
... different dosage com- pensation ...the X chromosome would face a greater dose imbalance due to faster Y chromosome gene loss, thus leading to the evolution of full compensation in XY ...
7
DOSAGE COMPENSATION OF GENES ON THE LEFT AND RIGHT ARMS OF THE X CHROMOSOME OF DROSOPHILA PSEUDOOBSCURA AND DROSOPHILA WILLISTONI
... MULLER (1950) pointed out that an understanding of the evolution of mecha- nisms for genetic adaptation, including that for dosage compensation, may be sought among spec[r] ...
8
Chromatin That Guides Dosage Compensation Is Modulated by the siRNA Pathway in Drosophila melanogaster
... male X (Deuring et ...the X chromosome and thought to participate in compensation (Jin et ...euchromatic chromosome arms, but the X chromosome is most severely affected ...
13
Fauth, Torsten (2010): Interaction of the Dosage Compensation Complex with DNA. Dissertation, LMU München: Fakultät für Biologie
... two X chromosomes would have the double amount of X-linked gene products as compared to the other sex with only a single X and a single gene-poor Y ...two X chromosomes of females is ...
110
Extreme heterogeneity in sex chromosome differentiation and dosage compensation in livebearers
... sex chromosome divergence began independently in ...Y chromosome in ...Y chromosome or an X0 ...Y chromosome is indeed ...the X is half that of females, consistent with large-scale loss ...
6
Dosage Compensation in Drosophila: Evidence That daughterless and Sex-lethal Control X Chromosome Activity at the Blastoderm Stage of Embryogenesis
... T h e most striking effect was the dramatic improvement of the segmentation phenotype of homozygous runt fe- males (Figure 3B) compared with that of hemizygous males (Figure 3A[r] ...
9
The C. elegans dosage compensation complex mediates interphase X chromosome compaction
... the X chromosome or chromosome I mask was calculated from the paint ...signals. Chromosome-paint signals were set as the secondary mask and for each object in the primary ...the X ...
16
Drosophila dosage compensation: a complex voyage to the X chromosome
... the X chromosome from autosomes, but also in the spreading of the MSL complex along this ...the X chromosome, with a bias for the bodies of active genes ...the X chromosome that ...
12