Xpert Mtb/rif
Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults
... of Xpert MTB/RIF sensitivity and speci- ficity to be lower in peripheral settings than in central and inter- mediate ...in Xpert MTB/RIF accuracy by ...of Xpert ...
326
Comparing laboratory costs of smear/culture and Xpert(®) MTB/RIF based tuberculosis diagnostic algorithms
... The simplified sequence of diagnostic tests in each algorithm and the action taken based on test results is shown. Abbreviations: TB - tuberculosis; LPA – Genotype MTBDRPlus line probe assay; DST - drug susceptibility ...
18
Original Article Evaluation of Xpert MTB/RIF in detection of pulmonary and extrapulmonary tuberculosis cases in China
... Xpert MTB/RIF is a TB-specific automated, car- tridge-based nucleic amplification assay with fully integrated and automated sample prepa- ration, amplification and detection of Mtb, as well ...
5
Comparison of Xpert MTB/RIF with ProbeTec ET DTB and COBAS TaqMan MTB for direct detection of M tuberculosis complex in respiratory specimens
... of Xpert MTB/RIF would perfectly match these ...the Xpert MTB/RIF is a self-contained, inte- grated test which requires hardly any training and can be also used in ...
6
Diagnostic Accuracy of IS6110 Insertion Gene, Hsp65, and Xpert MTB/RIF for Rapid Diagnosis of Pulmonary Tuberculosis
... Purpose: To evaluate diagnostic accuracy of IS 6110 insertion genes , hsp 65, and Xpert MTB/RIF for rapid diagnosis of pulmonary tuberculosis. Methods: Sixty patients, medically reported HIV ...
12
Containment of Bioaerosol Infection Risk by the Xpert MTB/RIF Assay and Its Applicability to Point of Care Settings
... (Xpert MTB/RIF product insert) before loading them into the Xpert MTB/RIF ...as RIF resistant by the Xpert MTB/RIF ...false RIF-resistant assay ...
7
Comparing laboratory costs of smear/culture and Xpert(®) MTB/RIF-based tuberculosis diagnostic algorithms
... and Xpert® MTB/RIF (Cepheid, Sunnyvale, CA, USA) (Xpert) hold the promise of improving TB and multidrug-resistant (MDR)-TB diagnosis as both are sensitive and faster than culture and ...
17
Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment
... quantitative outcomes and both were coded as 50 days and 50 cycles, respectively, if negative. Diagnostic test performance (sensitivity, specifi city, negative predictive value, positive predictive value) and Spearman ...
9
Comparison of Xpert MTB/RIF with Line Probe Assay for Detection of Rifampin Monoresistant Mycobacterium tuberculosis
... INNO-LiPA RIF TB (Innogenetics, Ghent, Belgium) and the Genotype MTBDRplus (Hain Life-Sci- ence, Nehren, Germany) (here referred as to ...and Xpert MTB/RIF assays have shown good performance ...
7
A model of tuberculosis screening for pregnant women in resource-limited settings using Xpert MTB/RIF
... As Xpert MTB/RIF instruments are reported to be simple enough to be run by lay workers this greatly increases the feasibility of using them in countries that have significant shortages of ...
5
Diagnosing Drug Resistant Tuberculosis with the Xpert®MTB/RIF The Risk for Rifampin Susceptible Cases
... of Xpert®MTB/RIF a real-time PCR (rt-PCR) assay that can both diagnose TB and detect rifampicin resistance con- currently, has revolutionized the diagnosis of drug-resistant tuberculosis (DR- ...the ...
7
Is Xpert MTB/RIF appropriate for diagnosing tuberculous pleurisy with pleural fluid samples? A systematic review
... of Xpert MTB/RIF using samples from patients confirmed by culture alone is likely to overestimate the sensitivity and underestimate the spe- cificity, as has been reported previously [5, ...
9
Evaluation of the Xpert MTB/RIF test for the diagnosis of childhood pulmonary tuberculosis in Uganda: a cross sectional diagnostic study
... the Xpert MTB/ RIF ...the Xpert MTB/ RIF cartridges and sample reagents, we were unable to run the Xpert MTB/RIF test on the freshly collected sputum ...
8
Testing Pooled Sputum with Xpert MTB/RIF for Diagnosis of Pulmonary Tuberculosis To Increase Affordability in Low Income Countries
... individual Xpert MTB/RIF tests, the investigator was not blinded to the results of the other set of tests when performing a particular set of ...
7
Diagnostic Accuracy of Stool Xpert MTB/RIF for Detection of Pulmonary Tuberculosis in Children: a Systematic Review and Meta analysis
... the Xpert MTB/RIF assay (“stool Xpert”) for childhood ...stool Xpert compared to a microbiological reference stan- dard of conventional specimens tested by mycobacterial culture or ...
12
Preservation of sputum samples with cetylpyridinium chloride (CPC) for tuberculosis cultures and Xpert MTB/RIF in a low income country
... Sputum samples can lose viability during long-duration transportation over large distances, which increases con- tamination by environmental and commensal bacteria present in the sputum and suppresses growth of TB [6, ...
6
Diagnostic Accuracy of Xpert MTB/RIF for Extrapulmonary Tuberculosis Specimens: Establishing a Laboratory Testing Algorithm for South Africa
... but Xpert MTB/RIF’s performance was no different for those specimens with a clear appearance (sen- sitivity, 52% [95% CI, 44% to 60%] versus 48% [95% CI, 36% to 61%], ...for Xpert ...
6
Direct comparison of Xpert MTB/RIF assay with liquid and solid mycobacterial culture for quantification of early bactericidal activity
... The Xpert MTB/RIF assay (Xpert; Cepheid, Sunnyvale, CA) is a new nucleic acid amplification test (NAAT) detecting ...PCR. Xpert is rapid (less than 1 h of hands-on time), standardized, ...
6
Xpert MTB/RIF Assay Shows Faster Clearance of Mycobacterium tuberculosis DNA with Higher Levels of Rifapentine Exposure
... The Xpert MTB/RIF assay (Xpert; Cepheid, Sunnyvale, CA), an automated, cartridge-based semiquantitative PCR (sqPCR) as- say targeting the rpoB locus of Mycobacterium tuberculosis DNA, received ...
6
The Diagnostic Performance of the GenoType MTBDRplus Version 2 Line Probe Assay Is Equivalent to That of the Xpert MTB/RIF Assay
... the Xpert MTB/RIF assay was endorsed by the World Health Organization for use on patient material, regardless of the smear gradation ...The Xpert MTB/RIF assay is now being ...
5