Y. pestis
Transmission efficiency of the plague pathogen (Y pestis) by the flea, Xenopsylla skrjabini, to mice and great gerbils
... of Y. pestis by ...containing Y. pestis spiked de- fibrinated great gerbil blood ...to Y. pestis culturing and phage confirmation tests, while F1 antigens and anti-F1 antibodies ...
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Immunomodulatory Effects of Yersinia pestis Lipopolysaccharides on Human Macrophages
... Antagonistic activity of LPS-37 to stimulation of TLR4 in human cells. The suppressive effects of LPS-37 on the activa- tion of human cells with various ligands to extracellular TLR were also examined. We used Y. ...
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Genome Rearrangements of Completely Sequenced Strains of Yersinia pestis
... the Y. pestis strains isolated from these two regions have distinct biological ...representative Y. pestis strains, D106004 isolated from Apodemus chevrieri in the Yulong focus and D182038 ...
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Golubov, Andrey (2005): Comparative genome analysis of Yersinia. Dissertation, LMU München: Fakultät für Biologie
... rhamnose-positive Y. pestis strain G8786 from a vole (Microtus arvalis) in a plague endemic locus in the high mountainous Caucasus in Georgia, was ...the Y. pestis-specific plasmid pFra is ...
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Exposure to Yersinia pestis increases resistance to plague in black rats and modulates transmission in Madagascar
... of Y. pestis within its host depends on evasion of the host’s innate immune system [12], and on circum- venting phagocytosis and antimicrobial effectors ...
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Recent emergence of new variants of Yersinia pestis in Madagascar
... of Y. pestis were closely related to their respective bio- ...of Y. pestis into 16 ribotypes (11), and we found a close association between biovar Orientalis and ri- botype ...three Y. ...
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The Genetic Diversity and Evolution of Francisella tularensis with Comments on Detection by PCR
... and Y. pestis, comparing sensitivities and specificities of the two ...and Y. pestis indicated sensitivities of 250 genome equivalents or lower and the authors conclude that the system is both ...
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Phylogeography and molecular epidemiology of Yersinia pestis in Madagascar
... isolate collections, however, SNP genotyping provides the most robust phylogenetic reconstructions. SNP genotyping [1], ribotyp- ing [24], IS100 insertion element RFLP analysis [25], different region (DFR) analysis [26], ...
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Diagnostic Bioluminescent Phage for Detection of Yersinia pestis
... Yersinia pestis is a gram-negative member of the family En- terobacteriaceae, and the etiological agent of the plague, which is a zoonotic disease affecting rats, prairie dogs, and other ...rodents. Y. ...
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The Resistance to Plague Infection among Meriones persicus from Endemic and Non-endemic Regions in Iran: The Role of Gut Microbiota
... Meriones of each region were divided into six groups, each including 10 Meriones. Then, 2 ml of each diluted microbial solution was injected sub- cutaneously; the Meriones was transferred to a la- boratory and were ...
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Rapid and sensitive detection of Yersinia pestis by lateral flow assay in simulated clinical samples
... A previous study announced that LFA, based on puri- fied F1 from Y. pestis EV76 strain and using the paired format of polyclonal and monoclonal antibodies, serum detection limit could up to 3.3 ng/ml [17]. ...
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Mixed pneumonic plague and nosocomial MDR-bacterial infection of lung: a rare case report
... for Y. pestis infection but not for ...of Y. pestis which provide alternatives for plague treatment ...of Y. pestis strains from diverse sources to 12 antimicrobial agents and ...
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Multiplex Detection of Three Select Agents Directly from Blood by Use of the GeneXpert System
... Our assay took ⬍ 100 min from the start to the availability of results and was performed directly from patient blood. The assay uses completely hands-free inte- grated sample processing and detection, requiring only that ...
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Homology Analysis of Pathogenic Yersinia Species Yersinia enterocolitica, Yersinia pseudotuberculosis, and Yersinia pestis Based on Multilocus Sequence Typing
... 35 Y. pestis strains isolated from different natural plague foci in China, 15 were isolated from patients (seven from Yunnan Prov- ince, six from Qinghai Province, one from Gansu Province, and one from ...
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Kinetic analysis of yersinia pestis DNA adenine methyltransferase activity using a hemimethylated molecular break light oligonucleotide
... Our initial investigations into the use of a DpnI cleavage assay to monitor Dam methylation began with a non-methylated break light oligonucleotide using a similar substrate to that of Li et al. [24]. We found that the ...
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Posttranscriptional Regulation of the Yersinia pestis Cyclic AMP Receptor Protein Crp and Impact on Virulence
... of Y. pestis) via a process known as catabolite repression (17, ...in Y. pestis, the Ysa T3SS and flagellum of Yersinia enterocolitica, and the virulence- associated Csr small RNAs (sRNAs) in ...
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Yersinia pestis Targets the Host Endosome Recycling Pathway during the Biogenesis of the Yersinia Containing Vacuole To Avoid Killing by Macrophages
... PFA-killed Y. pestis, ...by Y. pestis could alter several different aspects of macrophage biology that could impact ...Y. pestis infection. Several studies have shown that both ...
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In Vivo Transcriptional Profiling of Yersinia pestis Reveals a Novel Bacterial Mediator of Pulmonary Inflammation
... We observed that deletion of the ybtX gene resulted in dimin- ished disease symptoms during the proinflammatory disease phase but had no effect on bacterial burden or dissemination. Detailed examination of pulmonary ...
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Plague pandemics investigated by ribotyping of Yersinia pestis strains
... It seems probable that the Y pestis clone of ribotype B which caused the third pandemic derived from the first clone for at least two reasons: i the EcoRI and EcoRV patterns of ribotype [r] ...
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Gonzalez_unc_0153D_14326.pdf
... Y. pestis is considered to be responsible for three major pandemics in history: The Justinian Plague, The Black Death, and the Third Pandemic (Zietz and Dunkelberg, ...by Y. pestis, humans are ...
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