Y/sub 3/Fe/sub 5/O/sub 12/
In vitro toxicity of Fe<sub>m</sub>O<sub>n</sub>, Fe<sub>m</sub>O<sub>n</sub>-SiO<sub>2</sub> composite, and SiO<sub>2</sub>-Fe<sub>m</sub>O<sub>n</sub> core-shell magnetic nanoparticles
... 2 O 3 . Using TEM characterization, Fe m O n -SiO 2 composite flake-like and SiO 2 -Fe m O n core-shell IONPs demonstrated spherical shape with mean diameter of 98 ± 22 and 101 ± ...
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Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... saline). Fe 3 O 4 was washed twice with distilled water, dried, and suspended using normal saline (final concentration ...for 5 minutes at 2500 rpm; the supernatant was then removed and OD ...
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Magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells
... MNP-Fe 3 O 4 , adriamycin + MNP-Fe 3 O 4 , daunorubicin + MNP-Fe 3 O 4 , dexamethasone + MNP-Fe 3 O 4 , and RPMI 1640 alone were added ...
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The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... Nanotechnology offers an efficient alternative for cancer diagnostics and tumor target treatment due to the unique properties of nanostructures, such as large surface-to-volume ratio, porous structure, embedded effect, ...
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Effect of interaction of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and artesunate on apoptosis of K562 cells
... MNPs-Fe 3 O 4 , or the copolymer of ART with MNPs- Fe 3 O 4 in the presence or absence of 40 µ M Z-VAD-FMK for 48 ...L, 5 mg/mL) was added to each well and incubated for 4 ...
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Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... 8 O 6 ; Sigma-Aldrich ...(NaHCO 3 ; Sigma-Aldrich ...and 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyl tetrazo- lium bromide (MTT; Sigma-Aldrich ...
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Synergistic effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> with gambogic acid on apoptosis of K562 leukemia cells
... In order to examine the expression of caspase-3, bax, bcl-2, NF- κ B, and survivin, we next performed Western blot analysis on whole cell protein extracted from cells treated for 48 hours as described previously. ...
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Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... primer, 5 ′ -CACTTCACCGTCTT CCTCATT-3 ′ ; reverse, 5 ′ - TCTGCGTAGC TGCCAAACT-3 ′ ; β -actin (360bp) forward primer, 5 ′ -TTGCAGCTCCTTC GTTGCCG-3 ′ ; reverse, 5 ′ ...
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Preparation of Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles coated with gallic acid for drug delivery
... different pH levels which are similar to the pH of the stomach and the pH of the blood. Generally, the pH of the stomach varies from 1–2 to 4–5. After eating, the stomach releases proteases and hydrochloric acid ...
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Fe<sub>3</sub>O<sub>4</sub>-based PLGA nanoparticles as MR contrast agents for the detection of thrombosis
... and 12 h light/dark cycle) and had free access to water and ...Then, Fe 3 O 4 -PLGA or Fe 3 O 4 -PLGA-cRGD NPs at a final dosage of 1 mg lyophilized powder dissolving 1 mL ...
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Reversal of multidrug resistance by magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice
... This work was supported by National 863 Program Emphasis Project, Nanometer Biology Ware Study (No. 2007AA0222007), National Natural Science Foundation of PR China (No 30740062 and No 30872970), and High School Doctor ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... the Fe 3 O 4 -PLGA-PEG nanoparticles was also pH-dependent and enhanced at pH ...the Fe 3 O 4 -PLGA-PEG nanoparticles by a diffusion mechanism in ...
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Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... molecular weights. Immunoblots for expression of p38, p-p38, JNK, p-JNK, HO-1, ERK, c-Jun, cleaved caspase 3, Bcl2, Bax, P50, p53, Nrf2, Akt, and GAPDH were detected. All antibodies for Western blot in this study ...
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The effects of magnetite (Fe<sub>3</sub>O<sub>4</sub>) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH<sub>3</sub>) cells and in RAW 264.7 macrophages
... M Fe(II) and 1 M Fe(III) were prepared by dissolving FeCl 2 and FeCl 3 , ...produce Fe 3 O 4 NPs, 1 mL Fe(II) and 4 mL Fe(III) aqueous solutions were mixed at room ...
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Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... culture dishes; cells were either untreated (control), or treated with DTX (1 nM) or MgNPs-Fe 3 O 4 (10 µ g/mL or 100 µ g/mL) in the absence or presence of DTX (1 nM). Aspirated medium was collected ...
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The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... mg/kg Fe 3 O 4 - MNPs), medium-dose group (600 mg/kg Fe 3 O 4 -MNPs), and high-dose group (1200 mg/kg Fe 3 O 4 ...of Fe 3 O 4 - MNPs, ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... with Fe 3 O 4 -MNP increased to ...with Fe 3 O 4 -MNP- DNR-5-BrTet the temperature increased to ...with Fe 3 O 4 -MNP throughout the ...with Fe ...
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Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... for 5 minutes and dried in ...in 5 mL ...in 3% bovine serum albumin and phosphate-buffered solution at 37 ° C for one hour to block excess active groups and nonspecific binding sites on the ...
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Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... with 5 mg EDC and 5 mg NHS for 30 minutes at room ...with 5 mg PLGA, then intermittently sonicated for 30 minutes at room ...with 5 mg EDC, 5 mg NHS, and 500 µ L DOX (2 ...for 3 ...
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Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>@Au composite magnetic nanoparticles in vitro and in vivo
... China). 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bro- mide (MTT) and dimethyl sulfoxide were obtained from Sigma-Aldrich (St Louis, ...OH 3 HCl, and potassium oxalate (Shanghai First Reagent ...
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