Yersinia pestis
Humoral and Cellular Immune Responses to Yersinia pestis Infection in Long-Term Recovered Plague Patients
... Y. pestis from the Rattus flavipectus plague foci in the Yunnan- Guangxi-Fujian provinces of China were recruited for blood sampling in May ...Y. pestis infection according to the clinical criteria and ...
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Identification and Characterization of Variable Number Tandem Repeats in the Yersinia pestis Genome
... Yersinia pestis, the infamous plague-causing pathogen, appears to have emerged in relatively recent ...Y. pestis ge- ...Y. pestis genome and occur frequently in gene coding ...
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Immunomodulatory Effects of Yersinia pestis Lipopolysaccharides on Human Macrophages
... from Yersinia pestis grown at either 27°C or 37°C (termed LPS-27 and LPS-37, ...Y. pestis cells grown at 27°C or 37°C (termed FKB-27 and FKB-37, ...Y. pestis causes infection in humans without ...
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Effects of temperature on the transmission of Yersinia Pestis by the flea, Xenopsylla Cheopis, in the late phase period
... Yersinia pestis, the causative agent of plague, is a Gram-negative bacterium that infects primarily rodents, but which may also infect a wide array of other mam- malian hosts, including ...Y. pestis ...
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PCR Detection of Yersinia pestis in Fleas: Comparison with Mouse Inoculation
... identifying Yersinia pestis-infected fleas has been inoculation of mice with pooled flea ...Y. pestis infection by fluorescent-antibody assay and/or ...Y. pestis in ...Y. pestis by PCR; ...
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Exposure to Yersinia pestis increases resistance to plague in black rats and modulates transmission in Madagascar
... Objectives: In Madagascar, plague (Yersinia pestis infection) is endemic in the central highlands, maintained by the couple Rattus rattus/flea. The rat is assumed to die shortly after infection inducing ...
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Development of In Vitro Correlate Assays of Immunity to Infection with Yersinia pestis
... of Yersinia pestis. However, strains of Y. pestis that are F1 ⴚ but still virulent have been isolated, and an in vitro assay, the results which can predict protection against both F1 ⴙ and F1 ⴚ ...
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Hfq Globally Binds and Destabilizes sRNAs and mRNAs in Yersinia pestis
... in Yersinia pestis, a causative agent of plague, by using cross-linking immunoprecipitation coupled with deep se- quencing (CLIP-seq) ...Y. pestis and that Hfq also globally binds noncoding small ...
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Posttranscriptional Regulation of the Yersinia pestis Cyclic AMP Receptor Protein Crp and Impact on Virulence
... pathogen Yersinia pestis, Crp regulates the expression of multiple virulence factors, including components of the type III secre- tion system and the plasminogen activator protease ...Y. pestis is ...
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Detection of Yersinia pestis fraction 1 antigen with a fiber optic biosensor
... A fiber optic biosensor was used to detect the fraction 1 (F1) antigen from Yersinia pestis, the etiologic agent of plague. The instrument employs an argon ion laser (514 nm) to launch light into a ...
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Rapid and sensitive detection of Yersinia pestis by lateral flow assay in simulated clinical samples
... Yersinia pestis is a slow-growing, non-motile, and non-spore-forming gram-negative coccobacillus ...Y. pestis, 1347– 1351), is a known flea-borne disease that can trigger large epizootics among the ...
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Detection and Identification of Ciprofloxacin Resistant Yersinia pestis by Denaturing High Performance Liquid Chromatography
... identify Yersinia pestis KIM5 ciprofloxacin-resistant isolates by analyzing the quinolone resistance-determining region (QRDR) of the gyrase A ...Y. pestis KIM5 strain gyrA QRDR from 55 ...
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Integral and peripheral association of proteins and protein complexes with Yersinia pestis inner and outer membranes
... Yersinia pestis, a Gram-negative bacterium, is the causative agent of the bubonic and pneumonic ...Y. pestis strains associated with high virulence have been divided into three classical biovars ...
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Genotyping of a Homogeneous Group of Yersinia pestis Strains Isolated in the United States
... Yersinia pestis, the causative agent of deadly plague, is considered a reemerging infectious disease and a significant biological terrorism ...Y. pestis from the United States by pulsed-field gel ...
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Early Divergent Strains of Yersinia pestis in Eurasia 5,000 Years Ago
... Y. pestis, ...genomes: Yersinia pestis CO92 genome including the associated plasmids pCD1, pMT1, pPCP1 (Parkhill et ...2001); Yersinia pseudotuberculosis IP32953 including the associ- ated ...
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Inhibition of Neutrophil Primary Granule Release during Yersinia pestis Pulmonary Infection
... of Yersinia pestis causes primary pneumonic plague, the most severe manifestation of plague that is characterized by a dramatic neutrophil influx to the ...Y. pestis growth in the airways. However, ...
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Use of O Antigen Gene Cluster Specific PCRs for the Identification and O Genotyping of Yersinia pseudotuberculosis and Yersinia pestis
... Yersinia pestis is a very recently evolved clone of Yersinia pseudotuberculosis serotype O:1b. This close relationship causes potential difficulties in DNA-based diagnostic methods. Analysis of the ...
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Yersinia pestis Subverts the Dermal Neutrophil Response in a Mouse Model of Bubonic Plague
... human Yersinia pestis infections result from introduction of bacteria into the skin by the bite of an infected ...Y. pestis can evade the host’s innate immune response and subsequently disseminate to ...
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Dual-Function Antibodies to Yersinia pestis LcrV Required for Pulmonary Clearance of Plague
... Yersinia pestis, the etiologic agent of bubonic, pneumonic, and septicemic plague, has been responsible for more human death than any other bacterial pathogen ...year. Yersinia pestis is ...
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Yersinia pestis Targets the Host Endosome Recycling Pathway during the Biogenesis of the Yersinia Containing Vacuole To Avoid Killing by Macrophages
... ABSTRACT Yersinia pestis has evolved many strategies to evade the innate immune ...Y. pestis prevents phagolysosome maturation and establishes a modi- fied compartment termed the ...
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