[PDF] Top 20 A Mouse Model for Human Norovirus
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A Mouse Model for Human Norovirus
... In addition to expression of nonstructural proteins from full- length genomes, capsid proteins are expressed from subgenomic RNAs during norovirus replication (10). Therefore, sections of intestine, spleen, and ... See full document
8
Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction
... Data from clinical trials for hemophilia B using adeno-associated virus (AAV) vectors have demonstrated decreased transgenic coagulation factor IX (hFIX) expression 6–10 weeks after administration of a high vector dose. ... See full document
16
A mouse model of human oral esophageal cancer
... Biology, Mouse and Cell Cul- ture Core Facilities, National Cancer Institute grant N01-CN-95031-72, Deutsche Krebshilfe grants D/96/17197 and 10-1656-Op1 ... See full document
10
Osteoclast independent bone resorption by fibroblast like cells
... (SCID) mouse coim- plantation model, isolated human PLFs from late-stage APL produced signs of bone ...microscopy, human PLFs that were cultured over extended periods of time on dentin slices ... See full document
11
Structure of Antibody-Neutralized Murine Norovirus and Unexpected Differences from Viruslike Particles
... Murine norovirus (MNV) is the only norovirus that can be grown in tissue culture, studied in an animal model, and reverse engineered via an infectious clone and to which neutralizing antibodies have ... See full document
10
T lymphocyte recruitment by interleukin 8 (IL 8) IL 8 induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo
... a human neutrophil and T cell chemoattractant in ...on human leukocyte migration, we examined the ability of rhIL-8 to induce human T cell infiltration us- ing a human/mouse ... See full document
12
PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium
... transgenic mouse model in which human PTEN is overexpressed in ductal and alveolar mammary epithelium during puberty, pregnancy, lactation, and ... See full document
12
Characterizing Human Norovirus Binding to Fresh Strawberries.
... dehydrated with a graded series of cold ethanol washes of 30%, 50%, 70%, 95%, and three times with100%, respectively. Samples were infiltrated in Spurr’s resin (Sigma Adrich) with vacuum, and then embedded in BEEM ... See full document
150
Pathogenesis of a Genogroup II Human Norovirus in Gnotobiotic Pigs
... We evaluated the gnotobiotic (Gn) pig as a model to study the pathogenesis of human norovirus (HuNoV) and to determine the target cells for viral replication. Sixty-five Gn pigs were inoculated with ... See full document
10
Induction of Tolerance to Human Arylsulfatase A in a Mouse Model of Metachromatic Leukodystrophy
... animal model for MLD. Repeated intravenous injection of human ASA (hASA) improved the nervous system pathology and function, but also elicited a progressive humoral immune response leading to treatment ... See full document
9
A large outbreak of acute gastroenteritis caused by the human norovirus GII.17 strain at a university in Henan Province, China
... full norovirus genomes were compiled using the SeqMan program in the Lasergene software package (DNASTAR, Version ...2-parameter model with MEGA 5 software (available at: ...Complete norovirus ge- ... See full document
9
Efficient Norovirus and Reovirus Replication in the Mouse Intestine Requires Microfold (M) Cells
... Noroviruses (NoVs) are nonenveloped, highly stable, positive- sense RNA viruses that infect hosts via the fecal-oral route (20). Little is known about NoV pathogenesis, including early events during infection of the ... See full document
10
Murine Norovirus: a Model System To Study Norovirus Biology and Pathogenesis
... of human norovi- rus infection are projectile vomiting and/or explosive, watery diarrhea, as well as low-grade fever, malaise, nausea, and ab- dominal cramping or pain ...of human norovirus ... See full document
9
Isolation and Propagation of Human Papillomavirus Type 16 in Human Xenografts Implanted in the Severe Combined Immunodeficiency Mouse
... the human xenograft athymic mouse model, neither HPV-40 nor HPV- LVX82/MM7 reproduced the intraepithelial neoplasia lesions with which they can be associated in the natural host ... See full document
6
Mixture models for gene expression experiments with two species
... mixture model utilizing information across two species was proposed to solve the fundamental problem of identifying differentially expressed genes in microarray experiments in order to potentially improve the ... See full document
12
Riera Tur, Irene (2019): Artificial amyloid-like aggregating proteins cause cytotoxicity in vitro and in vivo. Dissertation, LMU München: Fakultät für Biologie
... transgenic mouse model expressing full-length human mutant huntingtin with 97Q repeats [113]), reported a spatiotemporal analysis of HTT interacting proteins via affinity-purification mass ... See full document
195
Helminthostachys zeylanica alleviates hepatic steatosis and insulin resistance in diet induced obese mice
... of human hepatocytes, HuS-E/2 cells, with palmitate markedly increased lipid accumulation and treatment with the HZ extract significantly decreased lipid deposition and facilitated AMPK and ACC ... See full document
11
Evidence for Human Norovirus Infection of Dogs in the United Kingdom
... The absence of HuNoV-positive stool samples from dogs in this study is in contrast to the results of Summa et al. (17), who identified HuNoV RNA in 4/92 canine stool samples. However, their sampling strategy was ... See full document
11
Structural Basis for Norovirus Inhibition by Human Milk Oligosaccharides
... with human norovirus ...block norovirus infections. One study found that human milk was able to block genogroup I genotype 1 ...GII.4 norovirus strains from binding to saliva samples ... See full document
6
Automatically transforming pre- to post-composed phenotypes: EQ-lising HPO and MP
... Further mismatches resulted from missed or faulty iden- tification of the structure entity in the phenotype rep- resentation, for example when the affected anatomical structure is named differently in Mouse ... See full document
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