[PDF] Top 20 Analysis of simian immunodeficiency virus sequence variation in tissues of rhesus macaques with simian AIDS.

... The other striking feature of the tissue-derived env clones is the change at position 385 from D to N in the sequence Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest aci[r] ... See full document

... Retrospective analysis of animals with attaching and effac- ing ...retrospective analysis of animals dying with AIDS (n ⫽ 96) over a 2-year period was ...for rhesus macaques with ... See full document

... Immunohistochemistry and confocal microscopy imaging. Formalin-fixed, paraffin-embedded tissues from animals were sectioned at a thickness of 7 ␮ m. The following primary antibodies (Abs) were used: anti-CD163 mouse ... See full document

... Two different approaches were used to study virion clear- ance in rhesus macaques. One was to follow the disappearance of viral particles from plasma after intravenous bolus injection of viral particles ... See full document

... mucosal tissues in our cohort of SIV- infected Chinese RMs, we found that CD4 ⫹ and CCR5 ⫹ cells are detectable both in lymphoid aggregates ...to AIDS is closely as- sociated with a rapid, dramatic, and ... See full document

... two rhesus monkeys infected with SIVmac239on had to be euthanized at 20 and 30 weeks postinfection because of severe respiratory symptoms, anorexia, and poor ...lymphatic tissues, and a nearly complete loss ... See full document

... human immunodeficiency virus (HIV)-infected individuals (16, ...molecular analysis (5, 22, ...antigenic variation at a number of different genetic loci (14, 34, ... See full document

... and tissues of ART-treated SIV-infected RM ...and tissues using both liquid chromatography-tandem mass spectrometry (LS-MS/MS) and infrared matrix- assisted laser desorption-electrospray ionization ... See full document

... high virus load at 2 weeks followed by a decline of about 2 orders of magnitude for the remainder of the infection ...Histopathologic analysis at necropsy of Mmu 27626 re- vealed widespread lymphoid ... See full document

... Simian immunodeficiency virus (SIV)-infected rhesus ma- caques provide a good surrogate model for AIDS vaccine develop- ...SIV/SHIV-infected macaques have shown an important role ... See full document

... this analysis is shown in ...all tissues except genital ...then analysis and presentation of distributions were performed using SPICE version ... See full document

... the virus replication, and that has been observed before (1, 18, 20), is that both SIVCD154 and SIVCNTL are recombinant SIV ⌬ nef viruses that have an additional DNA sequence (the CD154 gene), which reduces ... See full document

... human immunodeficiency virus- infected humans and in simian immunodeficiency virus (SIV)-infected rhesus ...macaques. Rhesus macaques are a suitable animal ... See full document

... a rhesus cytomegalo- virus (RhCMV)-seronegative macaque was inoculated with simian immunodeficiency virus (SIV) 6 weeks after the sero- logical screen for ...of simian ... See full document

... for virus infection which is seeded with infected cells during acute ...which virus crosses the blood-brain barrier early after infection and can be detected in the neuropil and cerebrospinal fluid by 7 to ... See full document

... Statistical analysis was used to compare the survival and virus load among neonatal rhesus macaques infected with each of the three SIVmac isolates and to compare the growth rates between ... See full document

... Replication of type 1 human immunodeficiency viruses containing linker substitution mutations in the -201 to -130 region of the long terminal repeat.. Downloaded from http://jvi.asm.org/[r] ... See full document

... human immunodeficiency virus (HIV) vaccine is one of the defining scientific challenges of our ...In simian immunodeficiency virus (SIV)-macaque studies, peripheral CD8 T-cell immunity ... See full document

... human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus of macaque monkeys ...minimal sequence identity, and not all properties are shared by the ... See full document

... gp120 sequence that was found in only a minor fraction of the pro- viral population in the blood of the transmitter ...little sequence heterogeneity in two normally hypervariable regions of env ... See full document