[PDF] Top 20 The Artificial Kidney Initiation in Kidney Injury 2 (AKIKI2): study protocol for a randomized controlled trial

... At D0, demographic data and medical history, including the current clinical history with the reason for ICU ad- mission, Simplified Acute Physiology Score (SAPS) III severity score [18] and Sequential Organ Failure ... See full document

... We have considered the potential interactions between gemigliptin and cisplatin from the beginning of this study. First, cisplatin has no effect on hepatic cyto- chrome P450 3A4 (CYP3A4) in human liver microsomes ... See full document

... Acute kidney injury; anti- Xa: Antifactor Xa; AT: Antithrombin; CRP: C-reactive protein; χ 2 : Chi-squared; CUS: Compression ultrasound; CT: Computed tomography; CRRT: Continuous renal replacement ... See full document

... our trial we use the se- verity of AKI based on the KDIGO criteria to define ‘early’ and ‘late’ initiation of continuous ...Acute Kidney Injury Network (AKIN) criteria alone cannot predict the ... See full document

... liver injury; DM: diabetes mellitus; ECG: electrocardiogram; eGFR: estimated glomerular filtration rate; ESRD: end- stage renal disease; GGT: gamma-glutamyl transpeptidase; HDL-C: high density ... See full document

... entire study period and after 30 days from the end of the trial, adverse events (AE) will be reported and recorded in the participants’ ...the study groups will also be assessed by clinical ...the ... See full document

... a randomized blinded trial in patients with CKD stage II, hypertension and albuminuria (200 to 2,000 mg/g creatinine), but normal plasma total car- bon dioxide levels (equivalent to serum bicarbonate con- ... See full document

... NGAL is a novel biomarker that is upregulated early in the course of AKI [15]. Whole blood (0.25 to 0.50 mL) will be tested using a fluorescence immunoassay that operates on the Triage™ platform (Alere Inc.) and yields ... See full document

... two randomized controlled trials [3,4] have demonstrated that furosemide-induced diuresis with matched isotonic intravenous hydration using the Renal- Guard system reduces AKI in high-risk patients under- ... See full document

... for one additional day. Doppler measurements will be performed during CRRT for both groups before the switch (baseline, examination day 1) and after the switch (follow- up measurement, examination day 2) in the ... See full document

... five randomized controlled trials (RCTs) and reported a significant survival benefit when RRT was started ...in study quality, pub- lication bias, heterogeneous patient populations ... See full document

... RRT initiation has been evaluated in different population types ...RRT initiation were unable to draw definitive con- clusions owing to the scarcity of large-scale randomized controlled trials ... See full document

... this study is to evaluate the efficacy of both telephone-administered CBT and befriending on outcomes for patients with diagnosed COPD who have at least mild levels of depression and/or ... See full document

... are randomized to either the SocialVille or control training program, and complete a set-up visit (V3) in which they are provided with a study laptop with their corresponding training ...and trial ... See full document

... In a linear mixed model in a paired comparison, CysC values significantly differ in patients with and without AKI starting at time point T4 (end of operation). The dif- ference becomes increasingly more significant with ... See full document

... In two previously published meta-analyses evaluating the difference between both fluid types in unselected patient’s population involving surgical patients in perioperative period and kidney transplant in addition ... See full document

... brain injury may produce mass effects from hemorrhagic contu- sion or hematoma, which can induce herniation and brain stem compression, and the resultant may be coma, which is not usually immediate but develops in ... See full document

... A high-protein diet is known to be effective for body weight loss and subsequent weight maintenance in the general population [19–22]. Protein generally exerts a better satiety effect than carbohydrates and lipids ... See full document

... Methods/Design: This protocol consists of a cluster randomized controlled trial (CRCT) followed by a process and cost analysis. Only practices providing ambulatory primary care as their ... See full document

... and protocol of the Kidney Awareness Registry and Education (KARE) Study, a 2x2 factorial randomized controlled trial that examines the impact of a multi-level intervention on ... See full document