[PDF] Top 20 Aspirin for Venous Ulcers: Randomised Trial (AVURT): study protocol for a randomised controlled trial
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Aspirin for Venous Ulcers: Randomised Trial (AVURT): study protocol for a randomised controlled trial
... All randomised participants will receive aspirin or placebo for 24 weeks and will be followed-up for 25 weeks following ...the study, then participants will be asked to inform the study ... See full document
9
Aspirin for venous ulcers: randomised trial (AVURT): study protocol for a randomised controlled trial
... The AVURT is designed to inform the feasibility of a larger, confirmatory study of aspirin therapy for ...VLU. AVURT is a phase II randomised, double blind, parallel-group, placebo- ... See full document
9
Aspirin versus placebo for the treatment of venous leg ulcers—a phase II, pilot, randomised trial (AVURT)
... II, randomised, double-blind, parallel-group, placebo-controlled, efficacy ...for trial participants can be found in the study protocol, which has been published ...the trial ... See full document
10
Aspirin in venous leg ulcer study (ASPiVLU): study protocol for a randomised controlled trial
... Background: Venous leg ulceration is a common and costly problem that is expected to worsen as the population ...of ulcers remain unhealed after 2 years, and ulcer recurrence is ...in venous ... See full document
9
Non sedation versus sedation with a daily wake up trial in critically ill patients receiving mechanical ventilation (NONSEDA Trial): study protocol for a randomised controlled trial
... A study from USA in 1991 showed that almost all patients on ventilators were sedated, some by intermit- tent administration, while 62% received continuous intra- venous sedative infusion ...A study ... See full document
11
Supervised exercise training as an adjunctive therapy for venous leg ulcers: study protocol for a randomised controlled trial
... leg ulcers may take many months to heal (and some do not) and during this time they result in signifi- cant suffering for patients and represent substantial cost to the ...for venous ulceration and few ... See full document
11
Aspirin to inhibit SEPSIS (ANTISEPSIS) randomised controlled trial protocol
... ASPREE study rate of death was estimated to be ...be randomised to placebo and an event rate of ...for aspirin versus placebo ...ANTISEPSIS study is powered to detect an effect less than the ... See full document
7
The impact of maintaining serum potassium ≥3 6 mEq/L vs ≥4 5 mEq/L on the incidence of new onset atrial fibrillation in the first 120 hours after isolated elective coronary artery bypass grafting – study protocol for a randomised feasibility trial for the proposed Tight K randomized non inferiority trial
... central venous potassium ad- ministration in the early post-operative period, when oral supplementation is not possible, is time-consuming, costly, and associated with clinical risk: rapid infusion can prove fatal ... See full document
9
VenUS IV (Venous leg Ulcer Study IV) – compression hosiery compared with compression bandaging in the treatment of venous leg ulcers: a randomised controlled trial, mixed-treatment comparison and decision-analytic model
... synthesising trial effectiveness data from VenUS IV with other relevant RCTs ’ data within a ...single trial with a group for each treatment included in the ... See full document
326
Supervised exercise training as an adjunctive therapy for venous leg ulcers: study protocol for a randomised controlled trial
... Laser Doppler fluximetry and iontophoresis will be used to assess cutaneous microvascular function [31] in the gai- ter area of the affected leg. We will assess areas of skin that are in close proximity to the ulcer but ... See full document
10
Protocol for a randomised controlled trial of fetal scalp blood lactate measurement to reduce caesarean sections during labour: the Flamingo trial [ACTRN12611000172909]
... Observational studies suggest that fetal lactate concen- trations are constant during the first stage of labour in the absence of hypoxia, and that intrapartum lactate mea- surements are better than estimations of pH for ... See full document
10
Study protocol for a multicentre, randomised, controlled trial to assess the effectiveness of antimicrobial central venous catheters versus ordinary central venous catheters at reducing catheter related infections in critically ill Chinese patients
... initial study catheter through guide- wire exchange; (5) patients hospitalised for severe burn injuries; (6) patients with, in the opinion of the doctor, a situation that is not suitable for indwelling placement, ... See full document
6
Alternative forms of hydration in patients with cancer in the last days of life: study protocol for a randomised controlled trial
... Up to 200 patients will be included in the trial. Patients are eligible for inclusion if they have a diagnosis of cancer; are aged 18 years or above; have an estimated prognosis of ≤ 1 week; and are unable to ... See full document
8
Randomised Ambulatory Management of Primary Pneumothorax (RAMPP): protocol of an open-label, randomised controlled trial
... The Data Safety Monitoring Committee (DSMC) consists of independent experts (medical experts and a statisti- cian) external to a trial who assess the progress, conduct, participant safety and critical endpoints of ... See full document
7
A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: A proof of principle pilot study
... 2 study evaluating its use as an adjuvant treatment for MPE due to non-small cell lung cancer closed prematurely after 3 pa- tients were enrolled due to poor accrual ... See full document
16
Study Protocol ECSSIT – Elective Caesarean Section Syntocinon® Infusion Trial A multi centre randomised controlled trial of oxytocin (Syntocinon®) 5 IU bolus and placebo infusion versus oxytocin 5 IU bolus and 40 IU infusion for the control of blood loss at elective caesarean section
... all trial participants will receive a bolus, and thus we do not anticipate any differ- ences in rates of adverse events between the ...the Trial Steering ...the trial infusion and commence a known 40 ... See full document
10
The Nkateko health service trial to improve hypertension management in rural South Africa : study protocol for a randomised controlled trial
... the trial, all clinics will have an attached data clerk responsible for collecting identifiers of all consenting attendees of the chronic disease clinic to allow their identification in the MRC/Wits Agincourt ... See full document
10
Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial
... The trial has successfully completed its feasibility phase of the first 100 patients and is now into the final phase of recruitment in 22 neurosurgical centres throughout the ...the trial by a trial ... See full document
15
Prednisolone Trial: Study protocol for a randomised controlled trial of prednisolone for women with idiopathic recurrent miscarriage and raised levels of uterine natural killer (uNK) cells in the endometrium
... a randomised, double-blind, placebo controlled trial of prednisolone with a pilot phase to assess feasibility of recruitment, integrity of trial procedures, and to generate data to base future ... See full document
7
The effect of recombinant human thrombopoietin (rhTPO) on sepsis patients with acute severe thrombocytopenia: a study protocol for a multicentre randomised controlled trial (RESCUE trial)
... retrospective study, for patients with severe thrombocytopenia, rhTPO could rap- idly increase PCs, reduce 28-day mortality, and there were no severe adverse events during rhTPO ...the study, which was a ... See full document
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