[PDF] Top 20 Assembly of Infectious Herpes Simplex Virus Type 1 Virions in the Absence of Full-Length VP22
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Assembly of Infectious Herpes Simplex Virus Type 1 Virions in the Absence of Full-Length VP22
... the VP22 protein during HSV-1 ...recombinant virus which synthesizes low levels of truncated VP22 and examined its replication and competence in virion ...nuclear VP22 occurs in the ... See full document
14
Modified VP22 Localizes to the Cell Nucleus during Synchronized Herpes Simplex Virus Type 1 Infection
... of VP22 packaged into infectious virions differed from VP22 extracted from infected-cell nuclei in that the virion-associated form had a higher electrophoretic mobility in denaturing ...that ... See full document
13
Temporal Regulation of Herpes Simplex Virus Type 2 VP22 Expression and Phosphorylation
... The VP22 protein of herpes simplex virus type 2 (HSV-2) is a major component of the virion ...that VP22 is phosphorylated during infection, and phosphorylation may play a role in ... See full document
9
Microtubule Reorganization during Herpes Simplex Virus Type 1 Infection Facilitates the Nuclear Localization of VP22, a Major Virion Tegument Protein
... While VP22 localized to the nuclei of cells treated with the microtubule-depolymerizing agent nocodazole, either taxol or nocodazole treatment prevented optimal HSV-1(F) replica- tion in Vero ...of ... See full document
15
Herpes Simplex Virus Tegument Protein VP22 Contains an Internal VP16 Interaction Domain and a C-Terminal Domain That Are Both Required for VP22 Assembly into the Virus Particle
... of VP22 are packaged into virions ...the virions preparation in that study was so low that it may simply represent cellular contamination of the ...of VP22, we would postulate that the tar- ... See full document
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Nuclear Localizations of the Herpes Simplex Virus Type 1 Tegument Proteins VP13/14, vhs, and VP16 Precede VP22-Dependent Microtubule Reorganization and VP22 Nuclear Import
... of VP22, which are independent of HSV-1-induced microtubule ...incoming virus, it should be noted that our analysis focused on de novo synthesized gene ...(incoming) VP22 at infection times ... See full document
14
Characterization of a UL49-Null Mutant: VP22 of Herpes Simplex Virus Type 1 Facilitates Viral Spread in Cultured Cells and the Mouse Cornea
... Herpes simplex virus type 1 (HSV-1) virions, like those of all herpesviruses, are composed of a nucleocapsid harboring the double-stranded linear DNA genome, a ... See full document
12
Construction of an Excisable Bacterial Artificial Chromosome Containing a Full-Length Infectious Clone of Herpes Simplex Virus Type 1: Viruses Reconstituted from the Clone Exhibit Wild-Type Properties In Vitro and In Vivo
... type 1 (HSV-1) genomes into an F plasmid as bacterial artifi- cial chromosomes (BACs) (17, 36, ...of infectious virus is achieved by transfection of the BAC plasmid into mammalian ... See full document
10
Characterization of VP22 in Herpes Simplex Virus-Infected Cells
... native VP22 peak 1 form is not associated with VP16 and thus is an independent oli- gomer or an assembly with components other than ...hand VP22 peak 2 migrated in an overlapping pat- tern ... See full document
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Membrane Association of VP22, a Herpes Simplex Virus Type 1 Tegument Protein
... virion assembly (43, ...into virions and trafficking through the TGN are facilitated by specific amino acid se- quences (2–4, 47, 62, 64, 66, ...Since VP22 localizes to acidic compartments of the ... See full document
11
Herpes Simplex Virus 1 VP22 Regulates Translocation of Multiple Viral and Cellular Proteins and Promotes Neurovirulence
... which VP22 acted in promoting the redistribution of VP16, VP26, ICP0, ICP4, ICP27, and Hsc-70 to the cytoplasm in infected ...of VP22 in regulating the proper subcellular localization of a subset of viral ... See full document
14
Systematic Assembly of a Full-Length Infectious cDNA of Mouse Hepatitis Virus Strain A59
... a full-length infectious cDNA of TGEV except that it was not usually necessary to introduce mutations and new restriction sites into the wild-type virus genome to direct the ... See full document
14
Absence of Leukosis Virus Markers in Hamster Cells Transformed by Herpes Simplex Virus Type 2
... Figure 1 the following experiments were designed to represents an experiment carried out with the demonstrate the presence or absence of RNA 333-8-9 transformed cell line and a cell line[r] ... See full document
5
The Absence of DHHC3 Affects Primary and Latent Herpes Simplex Virus 1 Infection
... affected virus infectivity and localization of UL20 and gK in vitro ...on virus infectivity was not determined (37). HSV-1 UL11 is also palmitoylated, but palmitoylation is not required for its ... See full document
18
Mechanisms of herpes simplex virus type 1 reactivation.
... latent herpes simplex virus type 1 (HSV-1) infection (6), little is known about the mechanisms by which stress induces ...of infectious HSV-1 ... See full document
10
Genetic Analysis of the Role of Herpes Simplex Virus Type 1 Glycoprotein K in Infectious Virus Production and Egress
... varicella-zoster virus gly- coprotein I (gI) was shown to depend on two different deter- minants, one of which is a tyrosine-containing tetrapeptide related to endocytosis-sorting signals ...bies virus gE ... See full document
12
Characterization of Herpes Simplex Virus Type 1 RNA Present in the Absence of De Novo Protein Synthesis
... Honess and Roizman 10 proposed a regulatory role for the proteins encoded by the IE mRNA of HSV-1 that has been documented by many workers using wild-type virus in cyclo9 Downloaded from[r] ... See full document
19
A Network of Protein Interactions around the Herpes Simplex Virus Tegument Protein VP22
... that assembly of UL49A itself into the HSV-1 virion remains contentious (1, ...glycoprotein-tegument assembly demonstrates that recruitment of virion components into this complex is selec- ... See full document
12
Physical mapping and nucleotide sequence of a herpes simplex virus type 1 gene required for capsid assembly.
... 2169 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest In this report, we describe some phenotypic properties of a temperature-sensitive mutant of herpes simplex type 1 H[r] ... See full document
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RNAs Extracted from Herpes Simplex Virus 1 Virions: Apparent Selectivity of Viral but Not Cellular RNAs Packaged in Virions
... viral RNAs were detected in their capsid preparations. The authors concluded that the RNAs were packaged in capsids and virions in different compartments. The results however are marred by the observation that the ... See full document
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