[PDF] Top 20 Association between an insertion/deletion polymorphism in <em>IL-1A</em> gene and cancer risk: a meta-analysis

... The study selection procedure is shown in Figure 1. A total of 77 articles were identified that were relevant to the search terms. After screening the titles and abstracts, 64 articles were excluded for being irrelevant ... See full document

... increased risk of gastric ...the association between eNOS rs1799983, rs2070744, and iNOS rs2297518 polymorphisms and the risk of gastric cancer risk are conflicting and ... See full document

... present meta-analysis were robust and credible. The relationship between CD44 gene rs13347 polymorphism and cancer risk was assessed, and this SNP was associated with ... See full document

... the cancer has still remained unclear, we hypothesized that both the cytokines may affect the development of chronic inflammation fol- lowed by malignancy, coordinately or ...that IL-17A (-197G/A) ... See full document

... oral cancer, oral cavity cancer, pharyngeal cancer, laryngeal cancer, CYP1A1, cytochrome P450 1A1, rs1048943, polymorphism, and ... See full document

... for meta-analysis. Third, our analysis might overlook the possibility of gene–gene or SNP–SNP interactions or linkage disequilibrium between ...this gene ... See full document

... Systematic searches were conducted through the databases of Medline/PubMed, Embase, Web of Science, Wanfang Med Online, and Chinese National Knowledge Infrastruc- ture, with the following keywords: “lung cancer” ... See full document

... Statistical analysis was done using SPSS software version 20 (SPSS, Chicago, IL, ...The analysis of categorical vari- ables was done using the chi-square test and the continuous independent variables ... See full document

... ity, the fixed-effects model was chosen. The pooled odds ratios (ORs), together with 95% confidence intervals (CIs), were calculated to assess the strength of the relationship. The statistical significance of ORs was ... See full document

... XRCC1 gene might contribute to impair DNA repair, thus playing a role in heightening the risk of ...XRCC1 gene have been identified: amino acid substitution between arginine and glutamine at ... See full document

... calculated to assess the association between IL-2 gene poly- morphisms and cancer susceptibility. Five different ORs were used to compute: allele contrast model (G vs T), dominant model ... See full document

... the association between the NQO1 C609T polymorphism and prostate cancer before May ...significant association was found between the NQO1 C609T polymorphism and prostate ... See full document

... the association between interleukin-10 (IL-10 -1082A/G, -592C/A, and -819T/C) gene polymorphisms and risk of lung cancer, but these have revealed inconsistent ...relationship ... See full document

... were diverse and might affect the results of meta-analysis. Due to a lack of valid data pertaining to age and gender for all included studies, we could not evaluate their impacts on the pooled OR value. ... See full document

... genetic polymorphism of XPD and its contribution to CRC susceptibility; however, due to the interethnic heterogeneity of the disease, the limita- tions of statistical power in individual studies, small sample ... See full document

... statistical analysis. The associations with cancer risk were detected underlying genotyping models, including allele comparision, recessive model, dominant model, homozygote model and heterozy- gote ... See full document

... pooled analysis demonstrated significant evidence of association between IL-6 (-174G/C) and low risk of tuberculosis in dominant model (CC + GC vs GG: OR = ...Subgroup analysis ... See full document

... subgroup analysis based on sample type and clinical characteristics of liver ...liver cancer, which illustrated no infiltration of liver cancer ...significant association with the existence of ... See full document

... I/D polymorphism was associated with OA risk [12, ...similar between patients and healthy controls, while the I allele was a risk factor for early onset (defined as onset age ≤ 52 years) and ... See full document

... this meta-analysis, we revealed that carriers of GG or -/G genotype of OPN promoter rs17524488 (-156-/G) polymorphism were significantly associated with increased risk of cancer ... See full document