[PDF] Top 20 Association of Osteopontin Gene Single Nucleotide Polymorphism with Systemic Lupus Erythematosus.

... Systemic lupus erythematosus (SLE ) is a typical autoimmune disease characterized by abnormal immunologic ...SLE. Lupus nephritis is frequently associated with abnormal production of ... See full document

... for Systemic Lupus Erythematosus Genetics (SLEGEN), Harley JB, Alarcón-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL, Tsao BP, Vyse TJ, Langefeld CD, Nath SK, Guthridge JM, Cobb BL, Mirel ... See full document

... significant association between chromosome 2q37 gene loci and susceptibility to systemic lupus erythematosus (SLE) and just right the programmed cell death 1 (PDCD1) gene is ... See full document

... the association of three SNP at -1082, -819, -592 and haplotypes of IL-10 5’flank- ing region with systemic lupus erythematosus susceptibility in Han ... See full document

... disposed individuals at a higher risk of SLE (15). Cytotoxic T lymphocyte associated antigen 4 (CTLA-4) plays a key role in the regulation of T-cell stimulation and inhibits T-cell activation (16) .Reduced expression or ... See full document

... a single PCR amplification product of 480 base pairs represented an I/I homozygous individual, the presence of a single PCR amplification product of 193 base pairs represented a D/D homozygous individual, ... See full document

... associated/linked to those involved in systemic lupus erythematosus (SLE). Genomic DNA was isolated from 31 unrelated Caucasian SLE patients, 34 unrelated Caucasian normals, 5 multiplex American ... See full document

... which systemic inflammation enhanced by SLE induces dysbiosis of the subgingival microbiota and progression to ...the systemic immune response, leading to increased activity of SLE ... See full document

... of lupus- like autoimmunity [157,158], which provides further evidence that complement-deficient mice are a useful model to study the association between complement deficiency and SLE, first described in ... See full document

... an association between the presence of anti-Sm and higher hip bone mass was found, while the presence of anti-Ro was negatively associated with BMD in the ... See full document

... Even when the diagnosis of SLE has been established, the acutely ill patient must be thoroughly assessed before the illness is presumed to be due to a flare of their lupus. Since both SLE itself and the drugs used ... See full document

... significant association between the CCR5Δ32 mutations (heterozygous and homozygous alleles) and SLE patients in the Golestan ...this polymorphism in Turkmen patients was higher than that in other ethnic ... See full document

... The relationship between disease activity and fatigue is constantly researched and debated in the literature. Krupp et al., (1989) were one of the earliest researchers to examine this relationship when developing the ... See full document

... the association of a positive LBT and hypocomplementamia not only signifies the presence of lupus nephritis but also a more serious form of renal ... See full document

... recommended in APS patients (with or without SLE) with venous thrombotic recurrence or with arterial events. If indicated, direct oral anticoagulants (dabigatran, rivaroxa- ban or apixaban) could be used for VTE. Results ... See full document

... genome-wide association studies of SLE genetic ...IFN-a-regulated gene per se ...pediatric-onset systemic lupus erythematosus ... See full document

... Data were collected in forms and then transferred to SPSS software version 16 for data analysis. Non parametric variables such as number, percentage and mean + standard deviation (SD) were analyzed using descriptive ... See full document

... These receptors play a role in handling of immune com- plexes as well as in clearance of apoptotic cells. The Fc IgG receptor FcγRII and FcγRIII genes are both located at 1q23–24, and several polymorphisms have been ... See full document

... the association of CRP rs 1205 in relation to SLE risk and CRP levels in SLE and LN ...significant association of CRP rs 1205 with SLE and LN ...significant association with LN than in SLE (17 LN ... See full document

... e gene coding for the transcription factor IRF5 was the fi rst gene involved in IFNα production to be associated with SLE susceptibility ...genetic association between SLE and IRF5 and for interaction ... See full document