[PDF] Top 20 Association of SIRT6 Gene Polymorphisms with Human Longevity
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Association of SIRT6 Gene Polymorphisms with Human Longevity
... Therefore, SIRT6 activity is crucial in many chronic diseases and healthy longevity ...(11). SIRT6 knockout mice manifested kyphosis, cachexia, greying of fur, decreased bone mineral density, reduced ... See full document
7
Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity
... exceptional longevity when using other genetic models that were consistent with our results ...with longevity). In support of these results, a prior genome-wide longevity study found evidence of ... See full document
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Association of CCR2 Gene but not CCR5 Gene Polymorphisms with Alzheimer’s Disease
... in human postmortem brain microglia stimulated with Aβ belonge to the chemokine family ...of gene CCR5 protects individuals from early acute myocardial infarction (AMI) and severe ... See full document
6
Association of Polymorphisms in DAZL Gene with Male Infertility
... DAZ gene on the Y chromosome, DAZ-like (DAZL) gene on the 3p24, and BOULE gene on the 2q33 ...DAZL gene and DAZ genes on the Y chromosome in the coding region reaches up to 83% ...of ... See full document
8
<p>Association between heterozygote Val92Met <em>MC1R</em> gene polymorphisms with incidence of melasma: a study of Javanese women population in Yogyakarta</p>
... in human epidermis, the brownish-black eumelanin and the reddish yellow pheomelanin and is also affected by the environment where an ...of human skin color by binding α MSH, or ACTH results in stimulation ... See full document
7
Association of polymorphisms in <em>interleukin-8</em> gene with cancer risk: a meta-analysis of 22 case–control studies
... many human malignancies. Previous studies have uncovered that polymorphisms in IL-8 is associated with the risk of many cancer types, but the results were inconsistent and ...IL-8 polymorphisms ... See full document
11
Original Article Association of LIG4 and XRCC4 gene polymorphisms with the risk of human glioma in a Chinese population
... the association between LIG4 gene poly- morphisms and risk of glioma, only two previ- ous studies reported their association [14, ...rs7734849 polymorphisms contributed to glio- ma ... See full document
6
Genetic polymorphisms in DNA base excision repair gene XRCC1 and the risk of squamous cell carcinoma of the head and neck
... XRCC1 gene polymorphisms have been extensively studied in the association with various human cancers mostly breast, lung or head and neck ...national polymorphisms of four DNA repair ... See full document
7
<p>Genetic association of <em>XRCC5</em> gene polymorphisms with breast cancer among Jordanian women</p>
... ER), human epidermal growth factor receptor 2 (Her2) marker, extent of tumor differentia- tion (low vs middle and high), tumor size, lymph node involvement and ... See full document
6
Polymorphisms in the SNCA Gene: Association with the Risk of Development of the Sporadic Form of Parkinson’s Disease and the Level of SNCA Gene Expression in Peripheral Blood of Patients from Russia
... common human neurodegenerative disorders caused by the loss of dopa- minergic neurons in the ...(SNCA) gene is one of the most studied genes involved in the patho- genesis of ...single-nucleotide ... See full document
7
Original Article Association of estrogen receptor alpha gene polymorphisms and its gene-gene interactions with knee osteoarthritis susceptibility in Chinese Han population
... ESR1 gene were both associated with increased knee OA risk in Chinese ...the association between the human ESR1 gene polymorphisms and knee OA risk, previously several studies were ... See full document
7
Association of maternal KIR gene content polymorphisms with reduction in perinatal transmission of HIV 1
... The human killer immunoglobulin-like receptor (KIR) family of genes is part of the leuko- cyte receptor gene complex on chromosome 19 and comprises 16 individual KIR genes ...as gene content) and the ... See full document
15
Haptoglobin Genotypes And Longevity Among The Ghanaian Population
... candidate gene studies in associations in other populations [4],[5] necessitating the need for research into other candidate ...other longevity genes such as APOA1 [16] and APOE ...candidate gene for ... See full document
5
<em>SIRT1</em> gene polymorphisms and risk of lung cancer
... significant association between SIRT1 gene polymorphisms and human NSCLC, since we did not find any significant polymorphism of the SIRT1 gene in the NSCLC and control groups, SCC and ... See full document
6
Thrombophilic Mutations and Folate Gene Polymorphisms and Plasminogen Activator Inhibitor-1 in Russian Women with Unexplained Recurrent Early Spontaneous Abortion
... Significant association between heterozygotes genotype FVL 1691G/A and URESA was found ...low association with pregnancy loss ...PAI-1 gene 5G/4G genotype together with the MTHFR 677C/T or MTHFR ... See full document
7
Association of polymorphisms in <em>FADS</em> gene with age-related changes in serum phospholipid polyunsaturated fatty acids and oxidative stress markers in middle-aged nonobese men
... Genotype distributions in Hardy–Weinberg equilibrium with 41.0% GG, 47.5% GT, and 11.5% TT at position rs174537; 88.5% CC, 9.8% CG, and 1.6% GG at position rs174575; 48.4% CC, 44.3% CT, and 7.4% TT at position rs2727270; ... See full document
12
Association of genetic variations in the Wnt signaling pathway genes with myocardial infarction susceptibility in Chinese Han population
... CTNNB1 gene has multiple functions in the maintenance of cardiac tissue ...significant association between CTNNB1 rs2293303 C > T and breast cancer susceptibility ... See full document
11
Original Article Genetic association between CARD9 variants and inflammatory bowel disease was not replicated in a Chinese Han population
... no association with either CD or UC in the Chinese Han ...the association of one gene with complex diseases in one population cannot be exactly replicated in others ... See full document
6
Ataxia-telangiectasia: future prospects
... The human ATM gene is located at 11q22–23 and covers 160 kb of genomic DNA; the gene product, ATM protein, is produced from a 13 kb transcript that codes for a predicted 315 kDa ... See full document
9
Association of MBL2 gene polymorphisms with pulmonary tuberculosis susceptibility: trial sequence meta-analysis as evidence
... D) gene polymorphisms play a sig- nificant role in the risk of PTB ...MBL2 gene and infection or replication of ...D) gene polymorphisms and also aid in identifying the individuals ... See full document
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