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[PDF] Top 20 Autophagy regulates the stemness of cervical cancer stem cells

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Autophagy regulates the stemness of cervical cancer stem cells

Autophagy regulates the stemness of cervical cancer stem cells

... Competent cells were transformed with 2 µl of the ligated plasmid, plated with selection and single colonies were expanded prior to plasmid extraction using Maxiprep kit ... See full document

9

Autophagy regulates the stemness of cervical cancer stem cells

Autophagy regulates the stemness of cervical cancer stem cells

... Abstract: Cancer stem cells (CSCs) are a rare population of multipotent cells with the capacity to ...in cervical cancer ...that autophagy plays an important role in the ... See full document

9

A1E reduces stemness and self renewal in HPV 16 positive cervical cancer stem cells

A1E reduces stemness and self renewal in HPV 16 positive cervical cancer stem cells

... HaCaT cells. Furthermore, we investigated whether A1E can regulate cervical CSC self-renewal in HPV 16-positive SiHa and HPV 16-negative C33A cervical carcinoma ...SiHa cells inhibited EMT ... See full document

7

Characterization of cervical cancer stem cell-like cells: phenotyping, stemness, and human papilloma virus co-receptor expression

Characterization of cervical cancer stem cell-like cells: phenotyping, stemness, and human papilloma virus co-receptor expression

... studied cells with stemness and putative stem cell markers in cervical cancer cell lines growing in monolayer tissue culture conditions, it is necessary to claim for them the name ... See full document

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Matrix metalloproteinase-10 regulates stemness of ovarian cancer stem-like cells by activation of canonical Wnt signaling and can be a target of chemotherapy-resistant ovarian cancer

Matrix metalloproteinase-10 regulates stemness of ovarian cancer stem-like cells by activation of canonical Wnt signaling and can be a target of chemotherapy-resistant ovarian cancer

... cultured cells, and phosphorylation and cleavage of PDGFRα were not observed in MMP10-overexpressed cells (data not ...mammary stem cell, and growht of the mammary epithelial cells in vivo ... See full document

17

Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human cervical cancer cells

Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human cervical cancer cells

... gastrointestinal cancer pathogenesis [49, ...their cancer cells exhibit longer survival [51], and so Beclin1 expression has been postulated to act as a tumor suppressor ...and stem of ... See full document

16

Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity

Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity

... Cancer stem cells (CSCs) are endowed with stem cell properties, which include the ability to self-renew and differentiate by symmetrical or asymmetrical cell div- ...progenitor cells ... See full document

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LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells

LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells

... bladder cancer cells and the epithelial-to-mesenchymal transition ...promotes cancer progression and might act as an miRNA molecular ...the stemness properties and tumourigenicity of human ... See full document

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<p>High-Risk Human Papillomavirus E7 Maintains Stemness Via APH1B In Cervical Cancer Stem-Cell Like Cells</p>

<p>High-Risk Human Papillomavirus E7 Maintains Stemness Via APH1B In Cervical Cancer Stem-Cell Like Cells</p>

... Notes: (A) Heat-map of four stem cell pathway-related genes, WNT5B, APC2, WNT9A, and APH1B. (B) Real-time RT-PCR detection of the expression of WNT5B, APC2, WNT9A, and APH1B mRNAs in si-E7 and si-NC SiHa ... See full document

12

&lt;p&gt;PTPRU, As A Tumor Suppressor, Inhibits Cancer Stemness By Attenuating Hippo/YAP Signaling Pathway&lt;/p&gt;

<p>PTPRU, As A Tumor Suppressor, Inhibits Cancer Stemness By Attenuating Hippo/YAP Signaling Pathway</p>

... that regulates a variety of important cellular ...cancer cells. 20 These fi ndings suggested that the role of PTPRU during cancer development depends on the cellular signaling context and cell ... See full document

10

Role of autophagy in the maintenance and function of cancer stem cells

Role of autophagy in the maintenance and function of cancer stem cells

... in stem cell status has been identified within ...glioblastoma stem cells can differentiate towards neural and mesenchymal lineages(Ricci-Vitiani et ...Moreover, cancer cells may ... See full document

15

IL-8 regulates the stemness properties of cancer stem cells in the small-cell lung cancer cell line H446

IL-8 regulates the stemness properties of cancer stem cells in the small-cell lung cancer cell line H446

... sphere cells transfected with siil-8 or negative control (sinc) was detected by ...sphere cells transfected with siil-8 or sinc was analyzed by ...sphere cells transfected with siil-8 or ...from ... See full document

9

Autophagy maintains the stemness of ovarian cancer stem cells by FOXA2.

Autophagy maintains the stemness of ovarian cancer stem cells by FOXA2.

... between autophagy and stemness [8].Autophagy involves the sequestration of cytoplasmic components within a double-membraned vesicle, and subsequent fusion with lysosomes to generate autolysosomes, in ... See full document

12

&lt;p&gt;CARF, As An Oncogene, Promotes Colorectal Cancer Stemness By Activating ERBB Signaling Pathway&lt;/p&gt;

<p>CARF, As An Oncogene, Promotes Colorectal Cancer Stemness By Activating ERBB Signaling Pathway</p>

... Calcium ions (Ca 2+ ) serve as a second messenger that plays important roles in fundamental cellular physiology, including gene expression, cell cycle, autophagy and apop- tosis. Ca 2+ activates downstream ... See full document

11

Hypoxia regulates TRAIL sensitivity of colorectal cancer cells through mitochondrial autophagy

Hypoxia regulates TRAIL sensitivity of colorectal cancer cells through mitochondrial autophagy

... mitochondrial autophagy as an adaptive metabolic response ...DLD1 cells grown under hypoxic conditions using the membrane potential-independent MitoTracker dye revealed a reduced staining intensity compared ... See full document

17

LncRNA &amp; Wnt signaling in colorectal cancer

LncRNA & Wnt signaling in colorectal cancer

... cancers. Suppression of H19 resulted in increased cell survival and reduced migration in CRC [61]. H19 inter- action with the miRNA let-7 and MYC is well known for tumor progression, however, recently microarray- based ... See full document

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Emerging role for leucine-rich repeat-containing G-protein-coupled receptors LGR5 and LGR4 in cancer stem cells

Emerging role for leucine-rich repeat-containing G-protein-coupled receptors LGR5 and LGR4 in cancer stem cells

... Notes: (A) The seven transmembrane domains of the GPCRs activate a panel of heterotrimeric G-proteins that differ at the level of their α-subunits. (B) Upon ligand stimulation of the GPCR, the α-subunit separates from ... See full document

10

Activation and regulation of the granulation tissue derived cells with stemness-related properties

Activation and regulation of the granulation tissue derived cells with stemness-related properties

... transient-amplifying cells retaining the BrdU label, BrdU was injected intraperitoneally once at 60 hours after wounding (a single BrdU labeling ...dermal cells or GTCs at 7 days after wounding were ... See full document

15

SP600125 enhances C-2-induced cell death by the switch from autophagy to apoptosis in bladder cancer cells

SP600125 enhances C-2-induced cell death by the switch from autophagy to apoptosis in bladder cancer cells

... in autophagy in PC3 cells [3], therefore, we examined whether C-2 could trigger autophagy in bladder cancer cells in this ...BIU87 cells were treated with C-2 in dose- or ... See full document

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Metastatic neuroblastoma cancer stem cells exhibit flexible plasticity and adaptive stemness signaling

Metastatic neuroblastoma cancer stem cells exhibit flexible plasticity and adaptive stemness signaling

... SH-SY5Y cells that have structured neurites, MSDACs are smaller in size and readily form organized tumorospheres (Figure ...activated stem cell characteristics and cell survival signaling in MSDACs (Figure ... See full document

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