[PDF] Top 20 Cell Surface Vimentin Is an Attachment Receptor for Enterovirus 71
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Cell Surface Vimentin Is an Attachment Receptor for Enterovirus 71
... maintaining cell shape and integrity of the cytoplasm and stabilizing cytoskeletal interac- tions ...formed cell lines ...for surface vimentin as a general attachment receptor ... See full document
18
Enterovirus 71 Uses Cell Surface Heparan Sulfate Glycosaminoglycan as an Attachment Receptor
... CHO-pgsA745 cell line lacks heparan sulfate and chondroitin sulfate proteoglycans, while the CHO-pgsD677 cell line lacks heparan sulfate proteoglycan but produces 15% of normal ... See full document
10
Amino Acid Variation at VP1-145 of Enterovirus 71 Determines Attachment Receptor Usage and Neurovirulence in Human Scavenger Receptor B2 Transgenic Mice
... IMPORTANCE Attachment receptors expressed on the host cell surface are thought to enhance EV71 infection by increasing the chance of encountering true ...using cell culture for some viruses, ... See full document
16
Cell Surface Nucleolin Facilitates Enterovirus 71 Binding and Infection
... of enterovirus 71 (EV71) remains mostly ambiguous, identifying the factors that mediate viral binding and entry to host cells is indispensable to ultimately uncover the mechanisms that underlie virus ... See full document
12
Cell and tissue tropism of enterovirus 71 and other enteroviruses infections
... EV71 receptor on Jurkat T cells, is primarily expressed on leukocytes, where it mediates interaction with selectins and thus serves a crucial function in inflammatory processes ... See full document
6
Surface vimentin is critical for the cell entry of SARS-CoV
... functional receptor for SARS-CoV both in vitro [5, 6] and in vivo ...intestinal cell lines failed to be infected by SARS-CoV [9, ...lectin receptor expressed on ... See full document
10
Metabolic labeling of enterovirus 71 with quantum dots for the study of virus receptor usage
... two receptor depletion cells, we found that cellular HS is dis- pensable for virus replication but can significantly induce virus binding to the cell ...EV71 receptor, has a lim- ited function in ... See full document
12
Sialylated glycans as receptor and inhibitor of enterovirus 71 infection to DLD 1 intestinal cells
... on cell surface, we tested whether depletion of glycolipids or glycoproteins (N- linked glycoprotein or O-linked glycoproteins) blocked EV71 infection, and sialidase depletion of SA residues on DLD-1 cells ... See full document
6
VP1 Amino Acid Residue 145 of Enterovirus 71 Is a Key Residue for Its Receptor Attachment and Resistance to Neutralizing Antibody during Cynomolgus Monkey Infection
... Thus, VP1-145 of EV71 might be a key residue not only for surface charge around the 5-fold axis of the virion but also for the structural properties of the whole virion. We found that relatively high ... See full document
17
The HeLa cell receptor for enterovirus 70 is decay-accelerating factor (CD55).
... HeLa cell membrane component that acts as the receptor for EV70, we chose to produce a MAb that would bind to the surface of HeLa cells and inhibit their infection by ...HeLa cell monolayers ... See full document
10
Functional Comparison of SCARB2 and PSGL1 as Receptors for Enterovirus 71
... The data suggest that SCARB2 is an authentic receptor for EV71. Only EV71 PB strains have adapted to use PSGL1 as a re- ceptor. The evolutionary significance of using PSGL1 as a receptor is not presently ... See full document
13
Fibronectin Facilitates Enterovirus 71 Infection by Mediating Viral Entry
... receptor required for the attachment of EV71 and was used as a positive control. The data indicate that FN plays a comparatively important role to SCARB2 for EV71 binding. Neither anti-SCARB2 nor anti-FN ... See full document
13
Outbreaks of enterovirus 71 infection
... with enterovirus 71 infec- ...by enterovirus 71 ...with enterovirus 71 ...by enterovirus 71 infection from Japanese encephalitis and other viral infections, such as ... See full document
8
Enterovirus 71 Disrupts Interferon Signaling by Reducing the Level of Interferon Receptor 1
... The recent outbreak of enterovirus 71 (EV71) infected millions of children and caused over 1,000 deaths. To date, neither an ef- fective vaccine nor antiviral treatment is available for EV71 infection. ... See full document
10
Identification of molecular determinants of cell culture growth characteristics of Enterovirus 71
... The virulence determinants of Poliovirus and EV-A71 reported in previous studies served as references in this study to produce EV-A71 viruses that are have reduced virulence in cell cultures. An EV-A71 mutant ... See full document
12
Immunity to Avirulent Enterovirus 71 and Coxsackie A16 Virus Protects against Enterovirus 71 Infection in Mice
... antigen-presenting cell activation and thus antigen- presenting cell–T-cell interactions ...perhaps cell-mediated effects were probably essential to the viral clearance and hence clinical ... See full document
6
Enterovirus 71 in Malaysia: A decade later
... TREATMENT AND PREVENTION Management The majority of EV-71 cases are mild, do not require hospitalization, and can be treated symptomatically. However, the challenge, particularly during an outbreak situation with ... See full document
15
Host Factors in Enterovirus 71 Replication
... Furthermore, of those identified, much remains to be learned about how and exactly where in the cell they act. For instance, the ITAFs hnRNP A1, FBP2, and FBP1 discussed above, which associate with the EV71 IRES, ... See full document
9
Predicting Intraserotypic Recombination in Enterovirus 71
... model enterovirus is poliovirus (PV), the causative agent of poliomyelitis, a condition characterized by acute flaccid ...virus, enterovirus 71 (EV-A71), causes similar clinical outcomes in recurrent ... See full document
15
Modification of the Untranslated Regions of Human Enterovirus 71 Impairs Growth in a Cell-Specific Manner
... a Cell-Specific Manner Chee Choy Kok,* Patchara Phuektes, Emily Bek, and Peter ...Human enterovirus 71 (HEV71) is the causative agent of hand, foot, and mouth disease and associated acute ... See full document
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