[PDF] Top 20 Cellular phenotype impacts human immunodeficiency virus type 1 viral protein R subcellular localization
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Cellular phenotype impacts human immunodeficiency virus type 1 viral protein R subcellular localization
... that cellular phenotype may alter the requirement for Vpr during the course of productive viral replication ...that cellular phenotype and hence specific interactions with selected ... See full document
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Human Immunodeficiency Virus Type 1 Nucleocapsid Protein Nuclear Localization Mediates Early Viral mRNA Expression
... the cellular genome. Den- sitometer readings of the HIV-1 DNA bands reveal that sim- ilar amounts of HIV-1 DNA are integrated at 24 h postinfec- tion by both wild-type and mutant viruses, so ... See full document
11
Oligomerization within Virions and Subcellular Localization of Human Immunodeficiency Virus Type 1 Integrase
... the viral genome in the host DNA, a crucial step of the retroviral cycle (see references 2, 3, and 6 for ...the viral DNA are covalently joined to newly created 59 ends in the target DNA (12, 18, 22, 45, ... See full document
10
Control of Human Immunodeficiency Virus Type 1 RNA Metabolism: Role of Splice Sites and Intron Sequences in Unspliced Viral RNA Subcellular Distribution
... resistance phenotype used to gen- erate the cell line suggests that splicing factors are ...unspliced viral RNA throughout the nucleus suggests a random movement of the RNA destined for transport through ... See full document
11
Viral protein R of human immunodeficiency virus type 1 induces retrotransposition of long interspersed element 1
... the human genome, respectively ...single human cell contains more than 5 × 10 5 copies of L1, 80–100 of which are competent for retrotransposition (L1-RTP) ...alters cellular properties by causing ... See full document
16
Cellular and Viral Specificities of Human Immunodeficiency Virus Type 1 Vif Protein
... different subcellular locations, including cytosol, membrane, cytoskeletal, and nuclear fractions (5, 16, 17, 20), and in association with the viral Gag polyprotein ...this cellular specificity, it ... See full document
6
Human Immunodeficiency Virus Type 1 Matrix Protein Interacts with Cellular Protein HO3
... its subcellular localization was un- affected in the presence of ...of protein expression achieved in this system may have masked subtle ...the virus lipid bilayer while the C-terminal end of ... See full document
6
Longitudinal studies of viral sequence, viral phenotype, and immunologic parameters of human immunodeficiency virus type 1 infection in perinatally infected twins with discordant disease courses.
... each virus input and plasma dilution, the percent inhibition was calculated as follows: 100 2 (p24 antigen production in tubes containing serum/p24 antigen production in tubes with no serum) 3 ... See full document
10
Mapping and Characterization of the N-Terminal I Domain of Human Immunodeficiency Virus Type 1 Pr55Gag
... Subcellular localization of Gag proteins visualized by con- focal ...the cellular cytoplasm (29). We reasoned that if altered cellular distribution represents a true function contributed by ... See full document
12
Synergistic activation of the human immunodeficiency virus type 1 promoter by the viral Tat protein and cellular transcription factor Sp1.
... 3932 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest We have previously shown that the human immunodeficiency virus type 1 HIV-1 Tat protein can activate a synthetic pro[r] ... See full document
5
Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions.
... Cells were labeled with [3H]leucine, cell supernatants were harvested, and disrupted cells were fractionated into membrane, membrane wash, cytosolic, and postnuclear wash fractions and v[r] ... See full document
9
Mechanism of Borna Disease Virus Entry into Cells
... a cellular protease ...the protein, there is a motif of 5 arginine residues ...sequence R(K/R)(K/R)R recognized by furin, a cellular calcium-dependent, subtilisin-like ... See full document
6
Oxadiazols: a New Class of Rationally Designed Anti-Human Immunodeficiency Virus Compounds Targeting the Nuclear Localization Signal of the Viral Matrix Protein
... matrix protein (MA), integrase (IN), and viral protein R (Vpr), have been proposed as karyophilic agents that recruit the cellular nuclear import machinery to the ...the viral ... See full document
9
Subcellular localization of the Vif protein of human immunodeficiency virus type 1.
... To determine whether regions important for the association of Vif with membranes are also important for function, a transient complementation assay was used to examine the abilities of t[r] ... See full document
9
Modulation of Sp1 Phosphorylation by Human Immunodeficiency Virus Type 1 Tat
... of protein phosphatase 1 (PP1) and protein phos- phatase 2A ...or 1 nM calyculin A (lane 5), the amount of phosphorylated Sp1 increased by approximately ...to 1 nM) (15, ... See full document
15
Interaction of the Human Immunodeficiency Virus Type 1 Vpr Protein with the Nuclear Pore Complex
... of protein nuclear import have been described so far, the most extensively characterized of which is known as the classical pathway and is utilized by basic-type NLSs (34, 35, ...other viral ... See full document
10
A human chromosome 12-associated 83-kilodalton cellular protein specifically binds to the loop region of human immunodeficiency virus type 1 trans-activation response element RNA.
... a cellular factor or protein complex with Tat and that this protein com- plex then binds specifically to TAR RNA to activate viral transcription ...and human cells (11, 30, 41, 44) and ... See full document
7
Subcellular Localization and Integration Activities of Rous Sarcoma Virus Reverse Transcriptase
... and viral enzymes and may represent a poten- tial role for RT in the PIC (5, ...the viral DNA for processing and joining while the IN domain in the  subunit is functionally ... See full document
8
Effect of semen and seminal amyloid on vaginal transmission of simian immunodeficiency virus
... factors modulating the infectiousness of HIV-1 in genital fluids may play a key role in the efficacy of sexual trans- mission of HIV-1 [6-8]. Multiple studies reported that semen boosts HIV-1 ... See full document
9
Biochemical Analyses of the Interactions between Human Immunodeficiency Virus Type 1 Vpr and p6Gag
... Human immunodeficiency virus type 1 (HIV-1) encodes a 97-amino-acid accessory protein called Vpr (an initialism for viral protein ...the protein ... See full document
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