[PDF] Top 20 Cerebral malaria in children: using the retina to study the brain
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Cerebral malaria in children: using the retina to study the brain
... cause malaria in ...severe malaria and malaria-associated deaths worldwide, particularly in sub-Saharan Africa where severe malaria has a disproportionate impact on chil- dren 55 years of age ... See full document
24
Chitinase 3 like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case–control study of African children
... experimental cerebral malaria, but outcome is unaffected by Chi3l1 deletion The regulation and role of CHI3L1 in vivo were then in- vestigated using a murine model of ...of brain ... See full document
11
Brain swelling is independent of peripheral plasma cytokine levels in Malawian children with cerebral malaria
... in children with CM, but are thought to be involved in counteracting the effect of the pro-inflammatory cytokines and down-regulating their production ...this study are instead more consistent with ... See full document
11
Retinopathy in severe malaria in Ghanaian children overlap between fundus changes in cerebral and non cerebral malaria
... this study corroborates the point that the brain together with the retina may suffer from ischaemia in CM, since both form part of the central nervous system and share com- mon features in ... See full document
6
Decorticate, decerebrate and opisthotonic posturing and seizures in Kenyan children with cerebral malaria
... Cerebral malaria is one of the most common non-trau- matic encephalopathies affecting children worldwide and the most severe neurological complication of falciparum malaria ...in ... See full document
10
Elevated plasma von Willebrand factor and propeptide levels in malawian children with malaria.
... Severe malaria is commonly misdiagnosed in Africa, because a patient with severe disease of any cause may have a parasitaemia that is coincidental and not responsible for the illness ...to malaria and, on ... See full document
8
Brain magnetic resonance imaging in imported malaria
... of malaria, describing brain microhaemor- rhages in one adult and in sixteen children with cerebral malaria [10, ...11]. Using this highly sensitive technique, the frequency of ... See full document
6
Coagulation and the endothelium in malawian children with cerebral malaria
... autopsy study of fatal cerebral malaria demonstrated that even in the specialist research facility in Blantyre with highly experienced clinicians, 23% of patients who met this clinical definition of ... See full document
302
Acute Brain MRI Findings in 120 Malawian Children with Cerebral Malaria: New Insights into an Ancient Disease
... prospective study of brain MRI in children with acute CM (with and without malaria retinopathy), we noted that the basal ganglia were the most common area of involvement in the ret ⫹ ... See full document
7
Retinal Changes in Severe Malaria in Bangladeshi Children
... observational study was conducted at Department of Pediatrics of CMCH from February 2008 to January 2009 after obtaining approval from ethical committee of Chittagong Medical ...falciparum malaria were ... See full document
7
Cerebral malaria is associated with differential cytoadherence to brain endothelial cells
... severe malaria, as defined by WHO (2000). The study was in compliance with the principals of the Declaration of Helsinki and the Belmont ...the children was according to national guidelines with ... See full document
15
Brain swelling and death in children with cerebral malaria
... the children and their parents and guardians for participation in the study; the many skilled nurses and clini- cians who provided clinical care for the children on the re- search ward; ...ing ... See full document
12
Association of ADAMTS13 polymorphism with cerebral malaria
... in malaria patients may allow overproduction of ULVWF ...to brain microvascular ...in cerebral malaria [14]. The present study revealed that rs4962153-A of ADAMTS13 was significantly ... See full document
8
Molecular basis of human cerebral malaria development
... in malaria pathogenesis has been increasingly ...The study of miRNA expression in ECM and non-ECM revealed that miRNAs, ...to malaria pathogenesis in diverse diseases such as the inhib- ition of ... See full document
7
Activated Neutrophils Are Associated with Pediatric Cerebral Malaria Vasculopathy in Malawian Children
... with cerebral malaria (CM) sustain cerebral microvascular sequestration of Plasmodium falciparum- infected red blood cells ...young children are infected with ...Malawian children with ... See full document
12
Lack of Decline in Childhood Malaria, Malawi, 2001–2010
... in malaria prevalence, ...a malaria-like illness; alternatively, the facility might have reached its capacity to conduct malaria tests, and when that capacity was exceeded, patients were treated for ... See full document
7
Pentoxifylline as an adjunct therapy in children with cerebral malaria
... During the study, parasitaemia, glucose, and haematocrit were assessed 4-hourly until three consecutive slides were negative for parasites. Vital signs were assessed quarter- hourly during the first 4 hours and ... See full document
6
Cytokine profiles in Malawian children presenting with uncomplicated malaria, severe malarial anemia and cerebral malaria
... of study participants: Subjects were children with cerebral malaria, severe malarial anemia and uncomplicated malaria presenting to the Pediatric Accident and Emergency Clinic at Queen ... See full document
36
A quantitative brain map of experimental cerebral malaria pathology
... the brain during ECM? Whilst we did not observe any knob formation on Pb infected erythrocytes (and thus no knob-based cytoadhesion as is observed with Pf [9, 11, 63, 64]), we did observe the occasional electron ... See full document
37
Persistent Endothelial Activation and Inflammation After Plasmodium falciparum Infection in Malawian Children
... 2011. Children aged 1–12 years were recruited into 1 of 4 clinical cat- egories: (1) cerebral malaria (CM) cases, who ful fi lled World Health Organization (WHO) diagnostic criteria [6] and had at ... See full document
6
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