[PDF] Top 20 The characterisation of a T cell response to human rhinovirus
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The characterisation of a T cell response to human rhinovirus
... the response towards a Thl ...reactive response, the responder population could be primed with one serotype (HRV 15 or lA) and then restimulated by a variety of different serotypes or with a panel of ... See full document
226
Characterisation of and T cell responses to the P91A tumour minus antigen.
... the T cell and the ARC following an initial ...to T cell activation and selection is the finding that multiple T cell receptors are triggered by only a few MHC-peptide complexes ... See full document
326
Nitric Oxide Inhibits Rhinovirus-Induced Cytokine Production and Viral Replication in a Human Respiratory Epithelial Cell Line
... epithelial cell is the primary site of rhinovirus infection (6, ...of rhinovirus infec- tions, since cytotoxicity is not observed either in infected hu- man epithelial cell cultures (49) or in ... See full document
9
Myelin basic protein specific T lymphocyte repertoire in multiple sclerosis Complexity of the response and dominance of nested epitopes due to recruitment of multiple T cell clones
... The human T cell response to the myelin basic protein (MBP) has been studied with respect to T cell receptor (TCR) usage, HLA class II restriction elements, and epitope ... See full document
12
Rhinovirus Replication in Human Macrophages Induces NF-κB-Dependent Tumor Necrosis Factor Alpha Production
... but rhinovirus replication in macrophages has not been ...that rhinovirus replication in human macrophages causes activation and nuclear translocation of NF- B, leading to TNF- ␣ ...the ... See full document
11
Longitudinal Analysis of the Human T Cell Response during Acute Hantavirus Infection
... CD8 T cell response in a non-antigen-specific way by combining three activation mark- ...CD8 T cells might have been bystander activated by the inflammatory response associated with ... See full document
9
Eukaryotic Initiation Factor 4GII (eIF4GII), but Not eIF4GI, Cleavage Correlates with Inhibition of Host Cell Protein Synthesis after Human Rhinovirus Infection
... host cell protein synthesis (4, 21, ...host cell protein synthesis following poliovirus infection re- quires a second event in addition to the cleavage of eIF4G ... See full document
6
The human T cell immune response to Epstein Barr virus
... immune response to the Epstein-Barr virus (EBV) started with Nicole Le Douarin when, with one of us ...investigated cell lineage and tissue interactions in the developing bursa of Fabricius through ... See full document
8
Limited Breadth of a T-Helper Cell Response to a Human Immunodeficiency Virus Envelope Protein
... PFU by the intraperitoneal route) (33). The recombinant VV was prepared by substituting the 1035 envelope sequence for the BH10 envelope sequence in a pSC11-based VV recombination vector. The plasmid was transfected into ... See full document
6
Response to chemoradiatiotherapy in squamous cell carcinoma of the esophagus: evaluation of some prognostic factors
... Mutations of the tumor suppression antigen p53 are among the most commonly detected genetic abnormalities in human neoplasia in general and in squamous cell carcinomas in particular. The results of an ... See full document
8
A human T cell clone that mediates the monocyte procoagulant response to specific sensitizing antigen
... of human purified protein derivative of the tubercle bacillus (PPD)-reactive T cell clones was derived by cloning out of soft agar followed by cultivation on inactivated feeder cells in the presence ... See full document
5
How does rhinovirus cause the common cold cough?
... Physical disruption to airways described above is a well- characterised part of the pathophysiology of lung dis- eases including asthma and cystic fi brosis, but the role it plays in URTI, such as HRV, has only recently ... See full document
11
Nanomechanical sensing of the endothelial cell response to anti-inflammatory action of 1-methylnicotinamide chloride
... mechanical response of human dermal microvascular endothelial cells (HMECs) to incubation with MNA, as measured using nano- indentation spectroscopy with an AFM tip, could be effectively used as a ... See full document
11
Immunodominance of a low affinity major histocompatibility complex binding myelin basic protein epitope (residues 111 129) in HLA DR4 (B1*0401) subjects is associated with a restricted T cell receptor repertoire
... heterogeneous response to MBP is present, both at the level of fine epitope recognition (8–12) and T cell receptor us- age (43–45), although an association of the immunodominant central epitope of ... See full document
12
Human CD4+ T Cell Response to Human Herpesvirus 6
... CD4 T cell epitopes in HHV-6 is compli- cated by poor knowledge of the immune response to this virus, the low frequency of responding cells, the large number of proteins encoded by the HHV-6 genome ... See full document
17
Prostaglandin E Modulation of the Mitogenic Response of Human T Cells: DIFFERENTIAL RESPONSE OF T CELL SUBPOPULATIONS
... among human peripheral blood T cells and a 20-30% suppression of their blastogenic response to ...of T-cell populations demonstrating quite different responses to ...of ... See full document
9
Investigation of the Role of Protein Kinase D in Human Rhinovirus Replication
... We first examined if HRV16 activated PKD by analyzing cell lysates from virally infected HeLa cells and HBECs. Using antibodies that specifically recognize PKD1 and PKD2 phosphorylated in their activation loop at ... See full document
21
Analysis of the human T-cell response to picornaviruses: identification of T-cell epitopes close to B-cell epitopes in poliovirus.
... Twenty-nine individuals responded to poliovirus type 3, coxsackievirus B3, and encephalomyocarditis virus by proliferation of T cells, and from such cultures, 130 virus-specific T-cell l[r] ... See full document
11
Immunodominant T-Cell Epitopes in the VP1 Capsid Protein of Rhinovirus Species A and C
... stimulate T-cell proliferation in any of the donors in the cohort and presented an RS of ...of response between immunodominant regions and the homologue regions in the VP1 protein of the other ... See full document
13
Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab
... stimulation, cell pellets were snap fro- zen and processed for RNA extraction (Miltenyi RNA Iso- lation Kit), QA/QC testing, and hybridization on Agilent Whole Human Genome Oligo Microarrays (8 × 60K, ... See full document
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