[PDF] Top 20 Clinical effectiveness and cost effectiveness of continuous subcutaneous insulin infusion for diabetes : systematic review and economic evaluation

... alternative cost scenarios as outlined within the costs section ...literature review, the CORE model may have a tendency to overstate overall mortality within T1DM over longer time horizons, which may be ... See full document

... BG, insulin and urinary glucose excretion, hypoglycaemic and hyperglycaemic episodes, foot care, injections and urine ...their insulin doses to achieve preprandial values below 7 mmol/l and postprandial ... See full document

... the clinical effectiveness of inhaler devices for delivering β 2 ...in clinical efficacy between inhaler devices, but a pressurised metered dose inhaler with a spacer would appear to be more ... See full document

... the effectiveness data were sourced from a combination of published studies and the University of Cincinnati Mania Project database, and insufficient details are provided regarding the generalisability and ... See full document

... levels. Clinical effectiveness: miscellaneous outcome measures A miscellany of further outcomes were reported mostly from retrospective laboratory analyses of serum samples for surrogate markers of ... See full document

... be cost- effective for the treatment of patients who have experienced adverse events with older AEDs, who have failed to respond to the older drugs, or where such drugs are ...integrated economic analysis ... See full document

... the systematic review of clinical effectiveness (see section ‘Results of updated meta-analysis’, ...the evaluation, specifying the proportion of patients who would survive, die or ... See full document

... injecting insulin, the effect of having an inhaled option on the willingness to start insulin among people with poor diabetic control on oral drugs, and the effect on glycaemic ...the ... See full document

... of insulin pump ...A systematic review of the clinical effectiveness and cost-effectiveness of CSII therapy for T1D patients concluded that CSII provides advantages over ... See full document

... the cost-effectiveness of CSII pumps related to the second observed outcome – BMI, because an increase in children’ s weight as a result of their normal developmental growth was observed in the both ... See full document

... for continuous outcomes or pooled hazard ...of clinical and methodological hetero- geneity will be used to determine whether a fixed or random-effects model is the most appropriate, rather than relying on ... See full document

... [2]. Continuous subcutaneous insulin infusion (CSII) is considered an option for type-1 diabetic patients unsatisfactorily controlled with multiple daily injections ...man insulin in ... See full document

... 1 diabetes in pediatric ...regarding continuous subcutaneous insulin infusion in the very ...of insulin pump therapy in the under 6 age ...of clinical trials investigating ... See full document

... (i.e. diabetes versus non-diabetes) are due to diabetes per se rather than some other characteristics associated with ...of diabetes that are the most important disease- specific determinant ... See full document

... of cost- effectiveness in the cohort with suboptimal glycemic control at ...most cost-effective in those with poor- est glycemic control at ...to clinical practice in the Netherlands as the ... See full document

... 1 diabetes mellitus (T1DM) is a chronic autoimmune condition that requires life-long administration of ...novel insulin preparations, technological advances in insulin delivery and glucose ... See full document

... prescribing insulin pumps in the last few years as an alternative treatment option to ...via insulin pumps for different periods to manage adults with T1DM and how that impacted their ...commencing ... See full document

... opportunity cost is important, there can be a number of challenges with applying it within the context of economic evaluation ...opportunity cost is of non-health resources, ... See full document

... Group economic model assumed a cost of ...corresponding cost assumed in the two industry ...a cost per milligram of leucovorin of ...higher cost from the Roche submission, capecitabine ... See full document

... In general, the current study revealed that CSII therapy is feasible in routine diabetes care for chil- dren and adolescents. The cohort achieved a mean HbA 1c of 8.3%, which is not dissimilar from the mean ... See full document