[PDF] Top 20 Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression
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Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression
... ortholog, Meg3, also known as gene trap locus 2 (Gtl2), is located at distal chromosome 12 ...the Meg3 region died perinatally and had major skeletal muscle defects. MEG3 is expressed in many normal ... See full document
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<p>Long Non-Coding RNA TTN-AS1 Serves as a Competing Endogenous RNA of miR-195 to Facilitate Clear Cell Renal Cell Carcinoma Progression</p>
... Methods: A total of 145 paired cancer and normal tissues were collected from patients with ccRCC. The expression levels of TTN-AS1 and miR-195 in the tissues or cells were measured by RT-qPCR analysis. The ... See full document
7
Expression and clinical significance of long non coding RNA HNF1A AS1 in human gastric cancer
... Long non-coding RNAs (lncRNAs) are non-coding RNAs greater than 200 nucleotides ...main functions are related to modulation of gene expression networks ...with cancer ... See full document
7
Long noncoding RNA SNHG6 functions as a competing endogenous RNA by sponging miR-181a-5p to regulate E2F5 expression in colorectal cancer
... Background: Long noncoding RNAs (lncRNAs) have been identified as a novel class of regulators implicated in diverse biological processes in human ...a cancer-associated lncRNA, exerts critical ... See full document
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<p>Long Non-Coding RNA HOTAIR Modulates KLF12 to Regulate Gastric Cancer Progression via PI3K/ATK Signaling Pathway by Sponging miR-618</p>
... the cancer progression of various ...GC progression via miR-618/KLF12 ...endometrial cancer indicated that KLF12 facilitated tumor progression in endo- metrial cancer by ... See full document
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Long non-coding RNA PXN-AS1 suppresses pancreatic cancer progression by acting as a competing endogenous RNA of miR-3064 to upregulate PIP4K2B expression
... For miRNA loss-of-function, the use of miRNA anti- sense inhibitor oligonucleotides, knockouts and miRNA sponges have been described [18]. Although antisense miRNA inhibitors are especially useful for short term ex- ... See full document
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<p>Construction and Analysis of a Long Non-Coding RNA-Associated Competing Endogenous RNA Network Identified Potential Prognostic Biomarkers in Luminal Breast Cancer</p>
... Luminal BC is the most common type of whole BC. 9 Owing to advanced screening and endocrine therapy, some success in the treatment of luminal BC has recently been achieved. However, the mortality rate has not declined, ... See full document
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Original Article Up-regulated expression of long non-coding RNA ZFAS1 associates with aggressive tumor progression and poor prognosis in gastric cancer patients
... identification of GC associated lncRNAs and investigation of their clinical significance may provide a missing piece of the well known onco- genic and tumor suppressor network puzzle. Recently, lots of studies showed ... See full document
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Long noncoding RNA SNHG6 mainly functions as a competing endogenous RNA in human tumors
... to regulate CDYL expression by acting as a sponge of miR-101-3p ...adjacent non-tumor tissues, and its overexpression is related to tumor development and poor survival in ...cycle progression, cell ... See full document
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Original Article Long-chain non-coding RNA HOTAIR expression in tissue samples correlates with gastric cancer survival
... of gastric cancer ...tumor progression by activating Wnt sig- naling to promote proliferation and migration of tumor cells; increasing methylation of the PTEN promoter, thereby silencing PTEN ... See full document
7
Associations between polymorphisms of long non-coding RNA MEG3 and risk of colorectal cancer in Chinese
... and gastric cancer; they found an important role for H19 variants in gastric cancer carcinogenesis ...and progression of esophageal squamous cell carcinoma ...other cancer, ... See full document
6
Long non-coding RNA UFC1 promotes gastric cancer progression by regulating miR-498/Lin28b
... in gastric cancer whereby claudin-4 expression is reduced by miR-596 and miR-3620-3p, which are in turn bound by lncRNA-KRTAP5-AS1 and lncRNA-TUBB2A acting as ceRNAs, resulting in increased claudin-4 ex- ... See full document
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Long non-coding RNA HOTAIR functions as a competitive endogenous RNA to regulate PRAF2 expression by sponging miR-326 in cutaneous squamous cell carcinoma
... Target genes of miR-326 were screened through bioin- formatics prediction with TargetScan (http://www.targe tscan .org/), Starbase (http://starb ase.sysu.edu.cn/) and RegRNA (http://regrn a2.mbc.nctu.edu.tw/). The inter- ... See full document
13
Expressions of Long Non Coding RNAs in Carcinogenesis of Cervix: A Review
... Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleo- tides mostly transcribed by RNA which do not encode ...complexes, MEG3 associates with miRNA, CCAT2, MEG3, ... See full document
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The long noncoding RNA, TINCR, functions as a competing endogenous RNA to regulate PDK1 expression by sponging miR-375 in gastric cancer
... GC progression, we analyzed the expression of TINCR and miR-375 in tumor and adjacent tissue samples from 56 patients with ...competitive endogenous RNA (ceRNA) to regulate the expression of ... See full document
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Enhanced expression of long non coding RNA NEAT1 is associated with the progression of gastric adenocarcinomas
... mainly regulate the genes that correlated with cell growth but not the genes associated with can- cer ...of cancer cells were all enhanced by exogenous NEAT1 expression in ... See full document
6
<p>Long Noncoding RNA CCAT1 Functions as a Competing Endogenous RNA to Upregulate ITGA9 by Sponging MiR-296-3p in Melanoma</p>
... noncoding RNA (lncRNA) composed of more than 200 nucleotides in length and were commonly regarded as untranslational transcripts without protein- coding ...canonical competing endogenous ... See full document
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Long non-coding RNAs in ovarian cancer
... neighboring coding gene functions of up-regulated lncRNAs were primarily in- volved in the mitotic cell cycle, mitotic nuclear division, and the cell cycle, the neighboring coding gene function of ... See full document
13
Long non-coding RNA MEG3 suppresses survival, migration, and invasion of cervical cancer
... of MEG3-RAC1 by NCBI blast online ...that MEG3 overexpression induced repression of Rac1 mRNA and protein expression (Figure 4B and ...with MEG3 level in SCC tissues (Figure ... See full document
9
Role of lncRNAs in GI Cancer
... The future of lncRNA holds much promise. It could be the key in understanding the pathogenesis of various tumors. It will definitely play a major part in diagno- sis and prognostication of various cancers as has been ... See full document
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