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[PDF] Top 20 Comparison of the effectiveness and safety of topical versus intravenous tranexamic acid in primary total knee arthroplasty: a meta-analysis of randomized controlled trials

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Comparison of the effectiveness and safety of topical versus intravenous tranexamic acid in primary total knee arthroplasty: a meta-analysis of randomized controlled trials

Comparison of the effectiveness and safety of topical versus intravenous tranexamic acid in primary total knee arthroplasty: a meta-analysis of randomized controlled trials

... the topical adminis- tration of TXA and intravenous TXA for the management of blood loss during TKA were identified by two re- viewers; the search was performed in August ...amic acid” “total ... See full document

11

Should synovectomy be performed in primary total knee arthroplasty for osteoarthritis? A meta-analysis of randomized controlled trials

Should synovectomy be performed in primary total knee arthroplasty for osteoarthritis? A meta-analysis of randomized controlled trials

... after primary TKA with versus without synovect- omy [13, ...and safety of synovectomy was not ...new meta-analysis completely re- trieved the studies, selected high-quality ones, and ... See full document

8

Comparison of oral versus intra articular tranexamic acid in enhanced recovery primary total knee arthroplasty without tourniquet application: a randomized controlled trial

Comparison of oral versus intra articular tranexamic acid in enhanced recovery primary total knee arthroplasty without tourniquet application: a randomized controlled trial

... loss, knee function, and early recovery in primary ...recent meta-analysis has confirmed that tourniquet could increase the risk of thromboembolic events ... See full document

11

Is combined use of intravenous and intraarticular tranexamic acid superior to intravenous or intraarticular tranexamic acid alone in total knee arthroplasty? A meta-analysis of randomized controlled trials

Is combined use of intravenous and intraarticular tranexamic acid superior to intravenous or intraarticular tranexamic acid alone in total knee arthroplasty? A meta-analysis of randomized controlled trials

... this meta-analysis. Firstly, the present meta-analysis focused only on papers published in English; the ones that were reported in other languages may increase heterogeneity and change the ... See full document

9

Review Article Efficacy of combined tranexamic acid for total hip arthroplasty patients: a meta analysis of randomized controlled trials

Review Article Efficacy of combined tranexamic acid for total hip arthroplasty patients: a meta analysis of randomized controlled trials

... and safety of combined intravenous (IV) and topical administration of tranexam- ic acid (TXA) compared with IV-only administration of TXA for reducing blood loss during total hip ... See full document

12

Review Article Multiple doses versus single dose of intravenous tranexamic following total joint arthroplasty: a meta-analysis of randomized controlled trials

Review Article Multiple doses versus single dose of intravenous tranexamic following total joint arthroplasty: a meta-analysis of randomized controlled trials

... Total knee arthroplasty and hip arthroplasty (TKA and THA) have been quite successful sur- geries for many end-stage knee and hip diseas- es, in terms of pain relief and functional ... See full document

14

Review Article Topical fibrin sealant versus intravenous tranexamic acid in reducing blood loss during total joint arthroplasty: a systematic review and meta-analysis

Review Article Topical fibrin sealant versus intravenous tranexamic acid in reducing blood loss during total joint arthroplasty: a systematic review and meta-analysis

... Objective: Intravenous (IV) tranexamic acid (TXA) and topical fibrin sealant (FS) are two common agents that are used to decrease perioperative blood loss during total joint ... See full document

11

Original Article The efficacy and safety of oral tranexamic acid for reducing blood loss after total joint arthroplasty: a meta-analysis

Original Article The efficacy and safety of oral tranexamic acid for reducing blood loss after total joint arthroplasty: a meta-analysis

... This meta-analysis aimed to illustrate the efficacy and safety of oral tranexamic acid (TXA) for reducing blood lossafter total joint arthroplasty ...of Controlled ... See full document

9

Combined application versus topical and intravenous application of tranexamic acid following primary total hip arthroplasty: a meta analysis

Combined application versus topical and intravenous application of tranexamic acid following primary total hip arthroplasty: a meta analysis

... in total knee arthroplasty with satisfac- tory results ...no meta-analysis has evaluated the efficacy and safety of combined applica- tion versus topical or ... See full document

10

Combined use of intravenous and topical versus intravenous tranexamic acid in primary total knee and hip arthroplasty: a meta-analysis of randomised controlled trials

Combined use of intravenous and topical versus intravenous tranexamic acid in primary total knee and hip arthroplasty: a meta-analysis of randomised controlled trials

... Two reviewers independently scanned the abstracts of the potentially included studies. Subsequently, the full text of the studies that met the inclusion criteria was screened, and a final decision was made. Disagreement ... See full document

10

Comparison of intravenous and topical tranexamic acid in total knee arthroplasty

Comparison of intravenous and topical tranexamic acid in total knee arthroplasty

... clinical effectiveness of IV and topical TXA in primary TKA using a prospect- ive randomized controlled ...that topical TXA and IV-TXA have similar safety and efficacy for ... See full document

5

The efficacy and safety of combined administration of intravenous and topical tranexamic acid in primary total knee arthroplasty: a meta analysis of randomized controlled trials

The efficacy and safety of combined administration of intravenous and topical tranexamic acid in primary total knee arthroplasty: a meta analysis of randomized controlled trials

... Tranexamic acid (TXA) is a synthetic lysine analog, it can competitively inhibit the activation of plasminogen and plasmin binding protein [7, ...Several randomized controlled trials ... See full document

11

The efficacy of intravenous aminocaproic acid in primary total hip and knee arthroplasty: a meta-analysis

The efficacy of intravenous aminocaproic acid in primary total hip and knee arthroplasty: a meta-analysis

... proic acid could reduce postoperative Hb reduction [6, 10]. Our meta-analysis was consistent with these ...aminocaproic acid group was significantly higher than that in the control ...present ... See full document

8

Cementless versus cemented total knee arthroplasty in young patients: a meta-analysis of randomized controlled trials

Cementless versus cemented total knee arthroplasty in young patients: a meta-analysis of randomized controlled trials

... (3) comparison: cemented prosthesis; (4) outcome measures: at least one of the following outcome mea- sures was reported: functional outcomes, radiological evaluation, pain score, and complication; and (5) study ... See full document

11

Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta analysis

Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta analysis

... unpublished trials that showed a negative or an equivocal difference between the intervention and control ...sensitivity analysis here to explore the cause of this ... See full document

14

The efficacy of topical tranexamic acid in total hip arthroplasty: a meta analysis

The efficacy of topical tranexamic acid in total hip arthroplasty: a meta analysis

... (1) randomized controlled trials (RCTs) or co- hort studies (CSs); (2) participants underwent primary THA; (3) interventions including topical (intra-articular) and IV-TXA; and (4) ... See full document

7

Epsilon-aminocaproic acid versus tranexamic acid in total knee arthroplasty: a meta-analysis study

Epsilon-aminocaproic acid versus tranexamic acid in total knee arthroplasty: a meta-analysis study

... during total knee arthroplasty. The text words “aminocaproic acid”, “EACA”, “tranexamic acid”, and “TXA”, were used in combination with the medical subject headings “knee ... See full document

8

A meta-analysis of unicompartmental knee arthroplasty revised to total knee arthroplasty versus primary total knee arthroplasty

A meta-analysis of unicompartmental knee arthroplasty revised to total knee arthroplasty versus primary total knee arthroplasty

... present meta-analysis, we found a greater proportion of usage of augments, stems, and bone grafts and a thicker poly- ethylene component in the revised UKA group than in the primary TKA group; this ... See full document

9

Extramedullary versus intramedullary femoral alignment technique in total knee arthroplasty: a meta-analysis of randomized controlled trials

Extramedullary versus intramedullary femoral alignment technique in total knee arthroplasty: a meta-analysis of randomized controlled trials

... and Meta Ana- lyses (PRISMA) statement. We conducted this meta- analysis of all English and non-English articles identified from electronic databases including Medline, Embase, Cochrane Library, ... See full document

7

Combined use of topical intraarticular tranexamic acid and rivaroxaban in total knee arthroplasty safely reduces blood loss, transfusion rates, and wound complications without increasing the risk of thrombosis

Combined use of topical intraarticular tranexamic acid and rivaroxaban in total knee arthroplasty safely reduces blood loss, transfusion rates, and wound complications without increasing the risk of thrombosis

... After final implant fixation and removal of excess cement, gauze packing was performed, and the tourni- quet was deflated. Manual compression around the surgical field was applied until the cement had completely ... See full document

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