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[PDF] Top 20 Complement receptor 1 polymorphisms associated with resistance to severe malaria in Kenya

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Complement receptor 1 polymorphisms associated with resistance to severe malaria in Kenya

Complement receptor 1 polymorphisms associated with resistance to severe malaria in Kenya

... and resistance to severe ...for severe malaria, ...of severe malaria between the two sites on the basis of other genetic factors and/or differences in the malaria ... See full document

7

Toll like receptor polymorphisms in malaria endemic populations

Toll like receptor polymorphisms in malaria endemic populations

... been associated with protection and susceptibility to malaria, these associations may not exist in the Kenyan or Papua New Guinean populations examined ...were associated with resistance to ... See full document

10

Toll-like receptor polymorphisms in malaria-endemic populations

Toll-like receptor polymorphisms in malaria-endemic populations

... been associated with protection and susceptibility to malaria, these associations may not exist in the Kenyan or Papua New Guinean populations examined ...were associated with resistance to ... See full document

11

The swain-langley and McCoy blood group polymorphisms of complement receptor 1: role in severe plasmodium falciparum malaria

The swain-langley and McCoy blood group polymorphisms of complement receptor 1: role in severe plasmodium falciparum malaria

... This case-control study sought to establish any associations between McCb and SI2 and severe forms of malaria (cerebral malaria and severe malarial anaemia). 03) than individuals with th[r] ... See full document

210

Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya

Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya

... Methods: We determined the association between haplotypes of Fc γ RIIA-131Arg/His, Fc γ RIIIA-176F/V and Fc γ RIIIB-NA1/NA2 variants and severe malarial anemia (SMA; hemoglobin < 6.0 g/dL, any density parasitemia) ... See full document

10

Association of the Single Nucleotide Polymorphism and Haplotype of the Complement Receptor 1 Gene with Malaria

Association of the Single Nucleotide Polymorphism and Haplotype of the Complement Receptor 1 Gene with Malaria

... the polymorphisms of erythrocyte complement receptor type 1 (CR1) in patients with malaria have been extensively studied, a question of whether the polymorphisms of CR1 are ... See full document

8

Toll like receptor polymorphisms and cerebral malaria: TLR2 Δ22 polymorphism is associated with protection from cerebral malaria in a case control study

Toll like receptor polymorphisms and cerebral malaria: TLR2 Δ22 polymorphism is associated with protection from cerebral malaria in a case control study

... uncomplicated malaria, and future studies of longitudinal cohorts examining the intensity and frequency of uncomplicated malaria epi- sodes in children with different Δ22 and GT n genotypes may elucidate ... See full document

11

Expression of complement and toll like receptor pathway genes is associated with malaria severity in Mali: a pilot case control study

Expression of complement and toll like receptor pathway genes is associated with malaria severity in Mali: a pilot case control study

... uncomplicated malaria cases during the late convalescence time point can be interpreted two ...following severe infec- tion is ...intermittent malaria episodes occurred, this scenario is unlikely; ... See full document

12

Reduced Immune Complex Binding Capacity and Increased Complement Susceptibility of Red Cells from Children with Severe Malaria-Associated Anemia

Reduced Immune Complex Binding Capacity and Increased Complement Susceptibility of Red Cells from Children with Severe Malaria-Associated Anemia

... falciparum malaria causes 1–2 million deaths per ...cerebral malaria (CM) (coma). Red cells of children with severe malaria-associated anemia (SMA) have ac- quired deficiencies ... See full document

9

Duffy antigen receptor for chemokines gene polymorphisms and malaria in Mangaluru, India

Duffy antigen receptor for chemokines gene polymorphisms and malaria in Mangaluru, India

... was associated with increased susceptibility to vivax malaria [11], and in older work from India, no impact of the Duffy blood group genotypes on vivax or falciparum malaria was observed ... See full document

8

Polymorphisms in the glucocorticoid receptor gene that modulate glucocorticoid sensitivity are associated with rheumatoid arthritis

Polymorphisms in the glucocorticoid receptor gene that modulate glucocorticoid sensitivity are associated with rheumatoid arthritis

... Apart from the association between the polymorph- isms with susceptibility of disease we also investigated whether relative GC resistance could possibly lead to an earlier onset of RA and/or a more aggressive ... See full document

8

Complement activation in Ghanaian children with severe Plasmodium falciparum malaria

Complement activation in Ghanaian children with severe Plasmodium falciparum malaria

... In contrast, the present study did not find any relationship between anaemia and CD35 and CD55 levels. Unlike the current study, the previous studies did not use strictly defined patient categories and, in some cases ... See full document

9

Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

... groups: malaria patients, patients with other infections and a village ...population. Malaria patients were divided into sub-groups based on severity of the disease and dis- ease ...with severe ... See full document

9

Transfected HEK293 Cells Expressing Functional Recombinant Intercellular Adhesion Molecule 1 (ICAM-1) – A Receptor Associated with Severe Plasmodium falciparum Malaria

Transfected HEK293 Cells Expressing Functional Recombinant Intercellular Adhesion Molecule 1 (ICAM-1) – A Receptor Associated with Severe Plasmodium falciparum Malaria

... protein 1 (PfEMP1) domains, the DBLβ, mediates ICAM-1 binding of ...cerebral malaria are needed before the DBLβ domains can be put forward as vaccine candidates and go into clinical ...to ... See full document

7

Estrogen receptor 1 gene polymorphisms are associated with metabolic syndrome in postmenopausal women in China

Estrogen receptor 1 gene polymorphisms are associated with metabolic syndrome in postmenopausal women in China

... ESR2 polymorphisms with MetS and related components, especially obesity, and lipid and glucose me- tabolism, in postmenopausal Chinese Han ...AluI polymorphisms of the ESR2 gene were not associated ... See full document

8

Complement Receptor 3 Promotes Severe Ross River Virus-Induced Disease

Complement Receptor 3 Promotes Severe Ross River Virus-Induced Disease

... IL-6 receptor antibody (51, 52), suggesting that high levels of IL-6 within the diseased tissues may contribute to RRV ...that complement-dependent inflammatory cell activation represents an ... See full document

10

Polymorphisms in the Haem Oxygenase 1 promoter are not associated with severity of Plasmodium falciparum malaria in Ghanaian children

Polymorphisms in the Haem Oxygenase 1 promoter are not associated with severity of Plasmodium falciparum malaria in Ghanaian children

... the malaria season (June to August) in 1995, 1996 and 1997, as described in detail in earlier publications ...296 malaria patients were enrolled; 101 with uncomplicated malaria and 195 with ... See full document

9

Optimal treatments for severe malaria and the threat posed by artemisinin resistance

Optimal treatments for severe malaria and the threat posed by artemisinin resistance

... 1 Optimal treatments for severe malaria and the threat posed by 1 artemisinin resistance 2 Sam Jones, Parasitology Department, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United 3 Kingdom[.] ... See full document

19

Optimal treatments for severe malaria and the threat posed by artemisinin resistance

Optimal treatments for severe malaria and the threat posed by artemisinin resistance

... of severe malaria that was able to recover key clinical observations (based on circulating parasite numbers), and, with novel metrics, used to investigate the pathology of severe ...artemisinin ... See full document

11

Soluble human complement receptor type 1 inhibits complement-mediated host defense.

Soluble human complement receptor type 1 inhibits complement-mediated host defense.

... When rats were treated with sCR1 in vivo, their serum opsonizing activity was inhibited in a dose-dependent fashion. Whereas a dose of 10 mg of sCR1 per kg resulted in a 67% inhibition o[r] ... See full document

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