[PDF] Top 20 Comprehensive analysis of gene-expression profile in chronic obstructive pulmonary disease

... Results: A total of 39 up- and 15 downregulated DEGs were screened. Most of the upregulated genes were involved in the immune response process, while the downregulated genes were involved in the steroid metabolic ... See full document

... for comprehensive analysis of exercise capacity in patients with chronic obstructive pulmonary disease ...manifold analysis of exercise capacity in patients with ... See full document

... trary, the expression of miR-203 was reduced 55.0% and 60.8% in the cells treated by LPS for 15 min and 30 min (Figure 4B). However, the Figure 3. miR-203 represses TAK1 and PIK3CA expression by targeting ... See full document

... CDC: Comprehensive diabetes care; CHF: Congestive heart failure; CMMI: Center for Medicare & Medicaid Innovation; CMS: ...COPD: Chronic obstructive pulmonary disease; CPC+: ... See full document

... may therefore affect the regulation of cell-cell and cell-matrix adhesion and the extent of extracellular matrix degradation. So it is conceivable that mutations in ADAM33 might promote emphysematous changes, a main ... See full document

... Tanreqing injection is the combination of water-soluble natural products from five Traditional Chinese Medicines: Radix scutellariae, Flos lonicerae, Fructus forsythiae, Fel ursi, and Cornu saigae tataricae. Of them, ... See full document

... Alpha 1 antitrypsin deficiency, mmp12, hedge hog, Alpha nicotinic choline receptor are the major genes linked with COPD. Pi ZZ - homozygosity for the Z allele, is associated with severe α1-AT deficiency (less than 15 ... See full document

... and pulmonary function test pa- rameters into consideration according to COPD diagnosis GOLD guidance ...munologic disease, diagnosis of reversibility in re- spiratory functions, bullous emphysema related ... See full document

... mRNA expression pro fi le GSE100281, consisting of 79 COPD and 16 healthy samples, was acquired from the Gene Expression Omnibus ...enrichment analysis for the DEGs was carried out using the ... See full document

... Data are expressed as mean ± standard deviation unless oth- erwise stated. One-way analysis of variance with Bonferroni correction was used to compare more than two groups. Rela- tionships between variables were ... See full document

... Historic viral diagnostic techniques such as serology, culture, enzyme immunoassay, and immunofluorescence were limited by poor sensitivity, complex methodology and slow turn-around time which impeded their inclu- sion ... See full document

... CSA measurements were made using the following steps. The threshold technique was adopted for a lung field with attenuation between - 500 and - 1,024 Hounsfield units. Segmented images were converted to binary images ... See full document

... of chronic obstructive pulmonary disease (AECOPD) is a disease state characterized by expiratory airflow limitation, increasing dead space, and diaphragm dysfunction [1], and invasive ... See full document

... COPD is most often caused by smoking tobacco [5], but is also associated with air pollution [5] and occupational exposures to dusts and chemicals [5]. The disease is somewhat unique in the fact that it is ... See full document

... Chronic bronchitis is more prevalent in workers who are engaged in occupation exposing them to inorganic or organic dusts, or to other noxious gases. There are surveys which have demonstrated an accelerated ... See full document

... Current Trends in the Management of Chronic Obstructive Pulmonary Disease CONTINUING MEDICAL EDUCATION Current Trends in the Management of Chronic Obstructive Pulmonary Disease IBE Jill III C K Liam,[.] ... See full document

... This is the largest study to evaluate the impact of a stan- dardized, guideline-based electronic order set for AECOPD on hospital LOS. We performed two analyses: a compari- son of LOS before and after the order set was ... See full document

... The COPD assessment test (CAT) was recently developed as a short, simple instrument for qualifying the symptom bur- den of COPD in routine practice, and enables better commu- nication between patients and healthcare ... See full document

... of tiotropium and perhaps improve upon less desirable ones. Aclidinium bromide (previously known as LAS34273) is a novel muscarinic antagonist developed by Almirall SA (Barcelona, Spain). The US Food and Drug ... See full document

... a comprehensive systemic inflammatory profiling (white blood cells, neutrophils, CRP, fibrinogen, and CCL-18) of the COPD patients at baseline in the ECLIPSE cohort, classified by the incidence of hospital ... See full document