[PDF] Top 20 Non concealed placebo treatment for menopausal hot flushes: Study protocol of a randomized controlled trial

... and placebo briefing After informed consent is signed, a clinical interview in- quiring about hot flushes (duration, severity, bother- someness) and related medical characteristics is conducted (see ... See full document

... this randomized, single-site, single-blind, placebo-controlled trial, 84 eligible patients will be recruited and randomly assigned to either the acupuncture group ( n = 42) or the sham control ... See full document

... For treatment of hot flushes, acupuncture causes only minor side effects as opposed to conservative therapies, including HRT and non-hormonal agents, which cause more drastic adverse effects ... See full document

... the trial has been given (via e-mail) to all primary care units in the study ...the trial, recruitment strengthening is deemed necessary, other strategies will be considered and dis- cussed with the ... See full document

... and concealed from the researchers by a senior data manager who is not involved in the ...the study sites, in concordance with the CONSORT guidelines. This trial uses a prospective, ran- domized, ... See full document

... experimental, non-invasive techniques have been used to infer central pain ...this study as the primary mechanism outcome, is a specific QST measure that estimates ascend- ing pain facilitation at the ... See full document

... SNRIs; MAO-Is; lithium; laxatives; doxyorubicine; oral antihyperglycemic agents; antacids; indometacin; post- menopausal hormone substitution; colchicine; ethanol; other inhibitors of cytochrome P450 isoenzyme 3A4 ... See full document

... treating menopausal hot flashes included six randomized controlled trials (RCTs), which compared acupuncture with sham acupuncture, and they concluded that sham-controlled RCTs failed ... See full document

... this study we also included the Columbia- Suicide Severity Rating Scale (C-SSRS) which has demonstrated good convergent and divergent validity with other multi-informant suicidal ideation and behav- ior scales and ... See full document

... of treatment after 12 weeks in the two groups, using a two-sample ...using non-parametric ...or non-parametric methods. Subgroup analy- ses include per-protocol analyses to assess efficacy of ... See full document

... cell death [19, 20]. Daptomycin’s synergism with various beta-lactams has been demonstrated for several different Gram-positive cocci, notably S. aureus and Entero- coccus species [7, 21–26]. The therapeutically active ... See full document

... the treatment of seizures and postherpetic ...12-week, randomized, double-blind, placebo- controlled trial in 50 adults with cannabis dependence, 1,200 mg of gabapentin was divided into ... See full document

... Treatment will be stopped if the vaginal bleeding becomes severe and requires surgical intervention, or a diagnosis of silent miscarriage is confirmed upon a follow- up scan (i.e., the gestational sac or fetal ... See full document

... real placebo needle seems to be a better alternative to overcome this ...a placebo acupuncture needle sys- tem some years ago, a new and valid instrument to measure placebo effects has become ... See full document

... this study of Taiwanese women with predominant SUI, duloxetine 80 mg/day (40 mg twice daily) as measured by the primary efficacy analysis (median percent change in IEF/week) was noted to be significantly more ... See full document

... from randomized tri- als or represent a minority of enrolled ...of treatment strategies in this population are uncertain and not well ...of randomized trials and the results of recent cohort studies ... See full document

... This study is designed to provide evidence on the (cost-) effective- ness of low dose aspirin in comparison with placebo in preventing preterm birth in women with a history of spontaneous preterm ... See full document

... of study interventions), on day 1 (24 h after admission and after the second dose of study intervention), and on day 4 (after the last dose of study ...The study clinicians reviewed all ECG ... See full document

... current treatment protocols are frequently ineffective among young children and carry a risk for important potential side ...the treatment, in terms of adverse events; to describe metabolic changes ... See full document

... in the verum group (85%), of which three had chronic CH, became attack free in the 1st week after the injection com- pared to none in the placebo group (P = 0.0001). Among them, eight remained free from attacks ... See full document