[PDF] Top 20 Crystal Structure of the Measles Virus Nucleoprotein Core in Complex with an N-Terminal Region of Phosphoprotein
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Crystal Structure of the Measles Virus Nucleoprotein Core in Complex with an N-Terminal Region of Phosphoprotein
... RNA virus measles virus (MeV) is an important human ...The nucleoprotein (N 0 ) as- sembles with the viral RNA into helical ribonucleocapsids (NC) which are, in turn, coated by a ... See full document
9
Structure of the Paramyxovirus Parainfluenza Virus 5 Nucleoprotein in Complex with an Amino-Terminal Peptide of the Phosphoprotein
... PIV5 N shows the presence of the 3= end of the RNA facing toward the N ⫹1 ...of N⫹1 suggests that the 3= end of RNA is first released through the N ⫹1 protomer and is accessible for RNA ... See full document
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Structure of the Nucleoprotein Binding Domain of Mokola Virus Phosphoprotein
... the crystal packing interactions revealed that a positively charged region of P, previously shown to be involved in the interaction with N, interacts with four acidic C-terminal amino acids in ... See full document
8
Structure of Recombinant Rabies Virus Nucleoprotein-RNA Complex and Identification of the Phosphoprotein Binding site
... Rabies virus nucleoprotein (N) was produced in insect cells, in which it forms nucleoprotein-RNA (N-RNA) complexes that are biochemically and biophysically indistinguishable from rabies ... See full document
9
Crystal Structure of the Nipah Virus Phosphoprotein Tetramerization Domain
... Nipah virus P multimerization domain is a long, parallel, tetrameric, coiled coil organized with an N-terminal cap and a hydrophobic ...four crystal structures illustrate tetrameric coiled ... See full document
5
Crystal Structure of the Oligomerization Domain of the Phosphoprotein of Vesicular Stomatitis Virus
... the N-RNA template while the L polymerase reads the ...one N monomer at a time, dictating that the polymerase complex moves 6 nucle- otides each ...this crystal structure looks like a ... See full document
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Crystal Structure of the Marburg Virus Nucleoprotein Core Domain Chaperoned by a VP35 Peptide Reveals a Conserved Drug Target for Filovirus
... NP core/NPBP complex and the EBOV NP core/NPBP complex, we found that the N and C termini of the NPBPs are ...in complex. Biochemical assays demonstrated that the binding of NP ... See full document
13
Crystal Structure of the Core Region of Hantavirus Nucleocapsid Protein Reveals the Mechanism for Ribonucleoprotein Complex Formation
... hanta- virus NP, we found that the deep hydrophobic pocket inside the RNA-binding crevice is similar to the hydrophobic pocket in FIG 7 Epitopes in hantavirus NP core ...the structure of SNV NP ... See full document
14
Crystal Structure of Classical Swine Fever Virus NS5B Reveals a Novel N-Terminal Domain
... the structure and function of CSFV NS5B and, more importantly, to explore potential sites for CSFV drug development, we determined the crystal structure of CSFV NS5B at ...its ... See full document
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Active Borna Disease Virus Polymerase Complex Requires a Distinct Nucleoprotein-to-Phosphoprotein Ratio but No Viral X Protein
... delta virus ribozyme upstream of the 3⬘-terminal A ...3⬘- terminal A ...Sendai virus polymerase ...panhandle structure with an overhanging 3⬘ end of 3 and 4 nt, ... See full document
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Self-Association of Lymphocytic Choriomeningitis Virus Nucleoprotein Is Mediated by Its N-Terminal Region and Is Not Required for Its Anti-Interferon Function
... the virus polymerase (L protein) and the matrix Z protein, whereas the S segment encodes the nucleoprotein (NP) and the glycoprotein precursor ...NP-RNA complex that, together with the virus L ... See full document
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Crystal structure of Schmallenberg orthobunyavirus nucleoprotein RNA complex reveals a novel RNA sequestration mechanism
... Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across ...ribonucleoprotein complex (RNP). We recently ... See full document
9
Insights into the Evolution of a Complex Virus from the Crystal Structure of Vaccinia Virus D13
... their core jelly-roll domains colored light blue and salmon, and the turret domain and tower loops dark blue and red, ...respectively. N- and C-termini are shown as spheres and labeled. (C) ... See full document
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Identification and Characterization of the Binding Site of the Respiratory Syncytial Virus Phosphoprotein to RNA-Free Nucleoprotein
... of N. In order to characterize the region of P that specifically interacts with N to maintain it in an RNA-free form, named N 0 , one must first be able to obtain such an RNA-free N 0 ... See full document
13
High resolution structure of the n terminal endonuclease domain of the lassa virus L polymerase in complex with magnesium ions
... the crystal structure of the N-terminal region of the LCMV L protein (PDB: 3JSB) [24] reveals an endonuclease domain that is structurally homologous to the endonuclease domain of the ... See full document
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Inhibition of Ubiquitination and Stabilization of Human Ubiquitin E3 Ligase PIRH2 by Measles Virus Phosphoprotein
... domain region of the P protein by using a yeast two-hybrid ...a complex with MV N was able to redistribute hPIRH2 to outside the nucleus, within intracellular ... See full document
13
Actin-Modulating Protein Cofilin Is Involved in the Formation of Measles Virus Ribonucleoprotein Complex at the Perinuclear Region
... In measles virus (MV)-infected cells, the ribonucleoprotein (RNP) complex, comprised of the viral genome and the nucleocapsid (N) protein, phosphoprotein (P protein), and large protein, ... See full document
8
Identification of an RNA binding region within the N-terminal third of the influenza A virus nucleoprotein.
... deleted region is not required for RNA bind- ...the region extending from amino acids 161 to 254 affected the structure and/or the RNA binding domain of NP, although that effect could be compensated ... See full document
8
Structure and function of bicistronic RNA encoding the phosphoprotein and matrix protein of measles virus.
... of monocistronic cDNA clones representing the complete P (pcD-P8) and M (pcD-M2i) genes of measles virus (35; Wong et al., submitted).. were compared with bicistronic clone pcD-PM5d.[r] ... See full document
6
Structure of the C-Terminal Domain of Lettuce Necrotic Yellows Virus Phosphoprotein
... secondary structure elements and potentially also from the acquisition or loss of some secondary structure ele- ...the structure (46): a four-helix subdomain that contains the structurally homologous ... See full document
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