[PDF] Top 20 Current concepts in multiple sclerosis therapy

... progressive multiple sclerosis (2005 revised McDonald cri- teria), were older (median age 46 years), had an EDSS score of ...progressive multiple sclerosis patients were ... See full document

... Longitudinal Multiple Sclerosis Study in the US which looked at natural history of MS and The Global Adherence Project (GAP) conducted in twenty-two other countries, TOP MS had comparable proportions of ... See full document

... IFN- β during the conception period and the first weeks of pregnancy seems to be relatively safe. It has become increas- ingly common to continue IFN- β until pregnancy has been confirmed. Given that it is not known when ... See full document

... Unfortunately, the current immune-based therapies have little, if any, effect on MS progression. This situation calls for introduction and development of new molecules or thera- peutic systems, which could tackle ... See full document

... to therapy in individual ...to therapy, a rational approach is baseline assessment with follow-up at 3 or 6 months and again at 12 ...in therapy or the need for more frequent ...that therapy ... See full document

... of multiple neuro-motor systems in MS and consequentially the difficulty in identifying the probable source of a particular speech ...speech therapy because of the inevitability of further deterioration and ... See full document

... progressive multiple sclerosis, had a history of peptic ulcer or current symptoms of dyspepsia, diabetes mellitus, alcohol or drug abuse, major depression, cardiac or renal insufficiency, or other ... See full document

... While current evidence is not suffi- ciently robust to confirm an increased risk of developing MS in patients with prior EBV infection, research of the association remains plausible ... See full document

... The effects of exercise in PALS are not well understood, and the role of resistance and aerobic exercise, and fitness in gen- eral, for those with ALS does continue to be controversial. The role of exercise in ALS has ... See full document

... of therapy, of success rates (includ- ing long term versus short term), and of the safety of using angioplasty – a treatment developed for arteries – on jugular ...access therapy, clinicians often claimed ... See full document

... exciting concepts emerging in the treatment of multiple sclerosis include recombinant myelin, basic protein as a more specific antigen to induce oral tolerance instead of oral myelin, protein growth ... See full document

... Results: A total of 125 patients were included in the final analysis (62.9% female, mean age 44.5 years, 71.5% with relapsing-remitting MS diagnosis). The most important factor for patients was the possibility of ... See full document

... Group Therapy on Life Expectancy and Hope Rate of Patients with Multiple Sclerosis” shows that the average score of well-being and hope rate in Azemayesh group turned up to be significantly higher ... See full document

... A sense of control and active physical and mental participation is notably unique to PT in comparison to drug therapy. According to patients, benefits of medicine are less apparent, which often leads to ... See full document

... of therapy: the condition of the patient before treatment and adaptive changes during therapy, eg, certain human leukocyte antigen alleles, or single nucleotide polymorphisms in the interferon alpha/beta ... See full document

... the current position along with accepting the realities of the disease, the chronic nature, treatment, complications of the disease are symptoms of coping with the ... See full document

... Rapidly progressive course of very late onset multiple sclerosis presenting with Parkinsonism: case report. Multiple sclerosis[r] ... See full document

... This study reports on the current, actual, and desired informa- tion needs of MS patients in the early stages of their disease. Participants have identified that they receive most information from the MS Society ... See full document

... Adolescents’ dependence on long-term treatment, need for self-management, physical limitations, and unpredictabil- ity of the disease magnifies the differences between these youth and their peers, thus increasing the ... See full document

... in multiple central nervous system (CNS) path- ways collated as a composite score known as the glo- bal evoked potential (GEP) [2, 3] improved in all patients studied ( n = 6) ... See full document