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[PDF] Top 20 Daily interruption of sedation in critically ill children: study protocol for a randomized controlled trial

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Daily interruption of sedation in critically ill children: study protocol for a randomized controlled trial

Daily interruption of sedation in critically ill children: study protocol for a randomized controlled trial

... All study centers use a standardized sedation protocol that contains an algorithm for increasing and weaning of seda- tives and ...standardizes sedation management and allows nurses to adapt ... See full document

6

Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption

Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption

... SLEAP trial [8]. We included critically ill adults who were expected to require mechanical ventilation for longer than 48 hours and were receiving continuous infusions of opioids and/or ...the ... See full document

7

Enteral versus intravenous approach for the sedation of critically ill patients: a randomized and controlled trial

Enteral versus intravenous approach for the sedation of critically ill patients: a randomized and controlled trial

... present study brings to light the need for clinical/ cultural change [33] on two key points regarding the management of sedation ...this study is part of an educational research project, specific ... See full document

10

Optimizing antibiotic prescribing for acutely ill children in primary care (ERNIE2 study protocol, part B): a cluster randomized, factorial controlled trial evaluating the effect of a point-of-care C-reactive protein test and a brief intervention combined with written safety net advice

Optimizing antibiotic prescribing for acutely ill children in primary care (ERNIE2 study protocol, part B): a cluster randomized, factorial controlled trial evaluating the effect of a point-of-care C-reactive protein test and a brief intervention combined with written safety net advice

... for daily follow up during the ...this study. And last but not least, we would like to thank all the children and parents who took part in this ... See full document

9

Impact of early parenteral nutrition completing enteral nutrition in adult critically ill patients (EPaNIC trial): a study protocol and statistical analysis plan for a randomized controlled trial

Impact of early parenteral nutrition completing enteral nutrition in adult critically ill patients (EPaNIC trial): a study protocol and statistical analysis plan for a randomized controlled trial

... All medications received by the patients during ICU stay are registered. Every day the amount of kilocalories, lipids, proteins, carbohydrates delivered by either PN or EN are calculated from the PDMS in an automated ... See full document

11

Long term psychological effects of a no sedation protocol in critically ill patients

Long term psychological effects of a no sedation protocol in critically ill patients

... of sedation has ...nurse-implemented sedation protocol, including only bolus doses of sedation, could reduce the time patients received mechanical ...a daily interrup- tion of sedatives ... See full document

8

Functional electrical stimulation assisted cycle ergometry in the critically ill: protocol for a randomized controlled trial

Functional electrical stimulation assisted cycle ergometry in the critically ill: protocol for a randomized controlled trial

... a daily rate of strength loss between ...(ICUAW), sedation and immobility may be prolonged well beyond the first week, when established damage to the muscle has already ... See full document

11

Sedation and renal impairment in critically ill patients: a post hoc analysis of a randomized trial

Sedation and renal impairment in critically ill patients: a post hoc analysis of a randomized trial

... original study we included patients who were expected to receive mechanical ventilation for more than 24 ...of sedation because of increased intracranial pressure or undergoing thera- peutic ...without ... See full document

6

Decreasing Delirium through Music (DDM) in critically ill, mechanically ventilated patients in the intensive care unit: study protocol for a pilot randomized controlled trial

Decreasing Delirium through Music (DDM) in critically ill, mechanically ventilated patients in the intensive care unit: study protocol for a pilot randomized controlled trial

... be randomized to one of three arms (20 participants per arm): (1) personalized music, (2) non-personalized relaxing music, or (3) ...the trial design (recruitment, adherence, participant retention, design ... See full document

8

Lung Ultrasound Guided Fluid Management Protocol for the Critically Ill Patient: study protocol for a multi centre randomized controlled trial

Lung Ultrasound Guided Fluid Management Protocol for the Critically Ill Patient: study protocol for a multi centre randomized controlled trial

... Management Protocol for the Critically Ill Patient is a prospective, multi-centre, randomized controlled ...The trial intervention will start on ICU admission and will consist in ... See full document

9

Intensive care sedation: the past, present and the future

Intensive care sedation: the past, present and the future

... when sedation is managed with a sedation protocol that targets light ...multicenter randomized trial comparing PS with combined PS plus DSI in 423 critically ill ... See full document

7

Cerebral microembolism in the critically ill with acute kidney injury (COMET AKI trial): study protocol for a randomized controlled clinical trial

Cerebral microembolism in the critically ill with acute kidney injury (COMET AKI trial): study protocol for a randomized controlled clinical trial

... and Sedation Scale; RRT: Renal replacement therapy; SAPS: Simplified Acute Physiology Score; SF-36: Short Form Health Survey; SOFA: Sequential Organ Failure Assessment Score; SWI: Susceptibility-weighted ... See full document

9

Study protocol for a phase II dose evaluation randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study)

Study protocol for a phase II dose evaluation randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study)

... III trial, ongoing re- view, problem identification, with adjustments are im- ...ginal protocol included a second loading dose of cho- lecalciferol on day 3 (if the 25(OH)D level measured on day 3 was not ... See full document

13

Non sedation versus sedation with a daily wake up trial in critically ill patients receiving mechanical ventilation—effects on physical function: study protocol for a randomized controlled trial: a substudy of the NONSEDA trial

Non sedation versus sedation with a daily wake up trial in critically ill patients receiving mechanical ventilation—effects on physical function: study protocol for a randomized controlled trial: a substudy of the NONSEDA trial

... be randomized to one of the two groups within 24 h after ...be randomized within the first 24 h after ...Copenhagen Trial Unit according to a computer-generated allocation sequence with a variable ... See full document

10

Daily sedative interruption versus intermittent sedation in mechanically ventilated critically ill patients: a randomized trial

Daily sedative interruption versus intermittent sedation in mechanically ventilated critically ill patients: a randomized trial

... our study also has several limita- ...intermittent sedation would increase the number of mechanical ventilation-free ...of sedation, a non- inferiority design would probably have been a better ap- ... See full document

12

Non sedation versus sedation with a daily wake up trial in critically ill patients receiving mechanical ventilation (NONSEDA Trial): study protocol for a randomised controlled trial

Non sedation versus sedation with a daily wake up trial in critically ill patients receiving mechanical ventilation (NONSEDA Trial): study protocol for a randomised controlled trial

... hort study, which showed that continuous intravenous infusion of sedatives was associated with significantly lon- ger mechanical ventilation, increased length of stay in the ICU and in hospital, compared with ... See full document

11

Non sedation versus sedation with a daily wake up trial in critically ill patients recieving mechanical ventilation   effects on long term cognitive function: Study protocol for a randomized controlled trial, a substudy of the NONSEDA trial

Non sedation versus sedation with a daily wake up trial in critically ill patients recieving mechanical ventilation effects on long term cognitive function: Study protocol for a randomized controlled trial, a substudy of the NONSEDA trial

... of sedation are ...less sedation, namely shorter dur- ation of mechanical ventilation, lower morbidity and shorter length of stay in the ICU and in hospital ... See full document

8

Efficacy of chlorhexidine bathing for reducing healthcare associated bloodstream infections: a meta-analysis

Efficacy of chlorhexidine bathing for reducing healthcare associated bloodstream infections: a meta-analysis

... Second, most of the studies enrolled in this meta-anal- ysis were not high quality due to the open-label study design. Additionally, three of the five studies could not guarantee blinded studies. The studies for ... See full document

9

Nebulized heparin is associated with fewer days of mechanical ventilation in critically ill patients: a randomized controlled trial

Nebulized heparin is associated with fewer days of mechanical ventilation in critically ill patients: a randomized controlled trial

... The study drugs were well tolerated, and only 6% of scheduled doses were withheld in the heparin group and 4% of scheduled doses were withheld in the placebo ...of study days with blood-stained sputum was ... See full document

10

The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta analysis of randomized trials

The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta analysis of randomized trials

... in critically ill patients as a result of many factors including medica- tions ...in critically ill patients, 46 % of them had evidence of delayed gastric emptying ...non- critically ... See full document

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