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[PDF] Top 20 Discovery to Development: Insecticides for Malaria Vector Control

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Discovery to Development: Insecticides for Malaria Vector Control

Discovery to Development: Insecticides for Malaria Vector Control

... dress the issues of translation of laboratory results into real world situations; these tri- als must be conducted in a region where the malaria vector is endemic. In each phase, the insecticide is either ... See full document

10

Field-Caught Permethrin-Resistant Anopheles gambiae Overexpress CYP6P3, a P450 That Metabolises Pyrethroids

Field-Caught Permethrin-Resistant Anopheles gambiae Overexpress CYP6P3, a P450 That Metabolises Pyrethroids

... pyrethroid insecticides in the malaria vector Anopheles gambiae is receiving increasing attention because it threatens the sustainability of malaria vector control programs in ... See full document

10

Susceptibility of Anopheles gambiae to insecticides used for malaria vector control in Rwanda

Susceptibility of Anopheles gambiae to insecticides used for malaria vector control in Rwanda

... The fact that millions of nets may have lost their effec- tiveness and thus continue to expose mosquitoes to a sub- lethal dose of pyrethroids is of major concern, because this may contribute to the further ... See full document

11

ResistanceSim   development and acceptability study of a serious game to improve understanding of insecticide resistance management in vector control programmes

ResistanceSim development and acceptability study of a serious game to improve understanding of insecticide resistance management in vector control programmes

... of insecticides is the cornerstone of effective malaria vector ...of insecticides, predominantly pyrethroids, causing widespread insecticide resistance and compromising the effectiveness of ... See full document

44

Variations in susceptibility to common insecticides and resistance mechanisms among morphologically identified sibling species of the malaria vector Anopheles subpictus in Sri Lanka

Variations in susceptibility to common insecticides and resistance mechanisms among morphologically identified sibling species of the malaria vector Anopheles subpictus in Sri Lanka

... resistance development and establishing its underlying mechanisms in vector populations are therefore important for maintaining effective vector ...used insecticides such as DDT, malathion, ... See full document

9

Integrated vector management for malaria control in Uganda: knowledge, perceptions and policy development

Integrated vector management for malaria control in Uganda: knowledge, perceptions and policy development

... bat malaria and other vector-borne diseases ...for vector spe- cialists and an appropriate vector control ...for malaria control in ... See full document

10

A comprehensive testing cascade to identify resistance breaking repurposed insecticides for next generation vector control tools: screening a panel of chemistries against a malaria vector

A comprehensive testing cascade to identify resistance breaking repurposed insecticides for next generation vector control tools: screening a panel of chemistries against a malaria vector

... for malaria control: clothianidin is the active ingredient in two IRS products, SumiShield™ 50WG (from Sumitomo Chemical) and Fludora®Fusion (from Bayer Crop Science, in combination with deltamethrin); and ... See full document

21

A comprehensive testing cascade to identify resistance breaking repurposed insecticides for next generation vector control tools: screening a panel of chemistries against a malaria vector

A comprehensive testing cascade to identify resistance breaking repurposed insecticides for next generation vector control tools: screening a panel of chemistries against a malaria vector

... The authors have prepared a revised manuscript to address the comments of three reviewers. The title has been changed to more accurately reflect the scope of the study. We have updated the acronym ‘LN’ to ‘LLIN’ to ... See full document

25

A comprehensive testing cascade to identify resistance breaking repurposed insecticides for next generation vector control tools: screening a panel of chemistries against a malaria vector

A comprehensive testing cascade to identify resistance breaking repurposed insecticides for next generation vector control tools: screening a panel of chemistries against a malaria vector

... Of the 16 compounds which were thus judged to be active in tarsal contact assays, 11 were taken forward to the next stage in the testing cascade, fenazaquin had previously been rejected [r] ... See full document

22

A comprehensive testing cascade to identify resistance breaking repurposed insecticides for next generation vector control tools: screening a panel of chemistries against a malaria vector

A comprehensive testing cascade to identify resistance breaking repurposed insecticides for next generation vector control tools: screening a panel of chemistries against a malaria vector

... A screening cascade for evaluating the potential of existing insecticidal compounds for repurposing into control tools against malaria vectors has been developed. This was used to scre[r] ... See full document

30

Developing an expanded vector control toolbox for malaria elimination

Developing an expanded vector control toolbox for malaria elimination

... contact insecticides by treating clothing: Treating even the most basic garments and bed clothes with contact insecticides has long been known to protect against malaria exposure indoors and ... See full document

9

Biology and bionomics of malaria vectors in India: existing information and what more needs to be known for strategizing elimination of malaria

Biology and bionomics of malaria vectors in India: existing information and what more needs to be known for strategizing elimination of malaria

... the malaria control pro- gramme in a sequential ...differential development of resistance among the sympatric sibling species under similar selection pressure was observed [11, 15, ...decades, ... See full document

11

The past, present and future use of epidemiological intelligence to plan malaria vector control and parasite prevention in Uganda

The past, present and future use of epidemiological intelligence to plan malaria vector control and parasite prevention in Uganda

... and vector-based studies were undertaken to characterize the epidemiology of malaria in a government resettlement scheme of approximately 50,000 people in northern Kigezi district ... See full document

11

Susceptibility status of Anopheles arabiensis (Diptera: Culicidae) commonly used as biological materials for evaluations of malaria vector control tools in Madagascar

Susceptibility status of Anopheles arabiensis (Diptera: Culicidae) commonly used as biological materials for evaluations of malaria vector control tools in Madagascar

... The results of WHO bioassay test on An. arabiensis laboratory strain in the present study highlight the full susceptibility of this strain to insecticides. Compared to laboratory-reared An. arabiensis adults (KGB ... See full document

6

High level of resistance in the mosquito Anopheles gambiae to pyrethroid insecticides and reduced susceptibility to bendiocarb in north western Tanzania

High level of resistance in the mosquito Anopheles gambiae to pyrethroid insecticides and reduced susceptibility to bendiocarb in north western Tanzania

... To control malaria in Tanzania, two primary vector control interventions are being scaled up: long- lasting insecticide-treated nets (LLINs) and indoor residual spraying ...effective ... See full document

8

Monitoring the operational impact of insecticide usage for malaria control on Anopheles funestus from Mozambique

Monitoring the operational impact of insecticide usage for malaria control on Anopheles funestus from Mozambique

... of insecticides for and maintenance of large scale vector control ...Spatial Development Initiative (LSDI) includes the southern most provinces of ...sustained vector control and ... See full document

7

The transcription factor Maf S regulates metabolic resistance to insecticides in the malaria vector Anopheles gambiae

The transcription factor Maf S regulates metabolic resistance to insecticides in the malaria vector Anopheles gambiae

... A whole-genome microarray approach was used to deter- mine the effect of Maf-S knockdown on transcriptional profiles. The transcriptional profiles of Maf-S knockdowns were compared against a GFP injected control. ... See full document

11

Allelic Variation of Cytochrome P450s Drives Resistance to Bednet Insecticides in a Major Malaria Vector

Allelic Variation of Cytochrome P450s Drives Resistance to Bednet Insecticides in a Major Malaria Vector

... in malaria mortality (47%) [1], the disease remains a serious public health burden in the tropical world, with 584,000 deaths globally in 2013, of which 90% occurred in WHO African region, and mostly in children ... See full document

25

Prospects and recommendations for risk mapping to improve strategies for effective malaria vector control interventions in Latin America

Prospects and recommendations for risk mapping to improve strategies for effective malaria vector control interventions in Latin America

... in malaria surveillance and monitoring, more efficient use of control measures, prompt and efficient malaria treatment/drugs, and better integrated vector man- agement (IVM) implementation ... See full document

15

Modification of contact avoidance behaviour associated with pyrethroid resistance in Anopheles sinensis (Diptera: Culicidae)

Modification of contact avoidance behaviour associated with pyrethroid resistance in Anopheles sinensis (Diptera: Culicidae)

... to insecticides can be stimulus-dependent or independent ...in malaria vectors following long- term extensive usage of insecticides, including a switch toward outdoor feeding [12–17], change in ... See full document

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