[PDF] Top 20 DNA methylation and polyamines in embryonic development and cancer
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DNA methylation and polyamines in embryonic development and cancer
... Int J De\" BioI 39 737 757 (1995) 737 DNA methylation and polyamines in embryonic development and cancer OLLE HEBY' Department of Cellular and Developmental Biology, University of Urnes, Umea, Sweden[.] ... See full document
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DNA methylation and its role in the trophoblast cell lineage
... of DNA methylation in the embryonic cell lineage, the role in the trophoblast lineage has not been explored ...normal development until the blastocyst stage (Sakaue et ...that DNA ... See full document
9
Review of the development of DNA methylation as a marker of response to neoadjuvant therapy and outcomes in rectal cancer
... of methylation in specific sites as well as collaborative research with other well- established predictive markers such as KRAS mutation which has already been associated with CIMP ...potential methylation ... See full document
9
DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer
... identify DNA methylation related with subsequent development of invasive breast cancer, we fit Cox pro- portional hazards models to examine the association be- tween time-to-event data and the ... See full document
12
Altered methylation of glucosylceramide synthase promoter regulates its expression and associates with acquired multidrug resistance in invasive ductal breast cancer
... The development of a malignant disease occurs via a multistage process, including genetic and epigenetic ...the DNA sequence, and involves DNA methylation, histone acetylation and chromatin ... See full document
12
DNA methylation profile of the DKK2 gene as a biomarker in patients with colorectal cancer
... vertebrate development, the DKKs are involved in the formation of the head and limbs, in osteoblast differentiation, and in ocular ...prostate cancer (Hirata et ... See full document
11
Pan-cancer patterns of DNA methylation
... of DNA methylation DNA methylation usually occurs at cytosine-guanine (CpG) dinucleotides, where DNA methyltransferases (DNMTs) catalyze the transfer of a methyl group to pos- ition 5 ... See full document
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Changes in DNA methylation are associated with the development of drug resistance in cervical cancer cells
... in DNA methylation may affect cellu- lar sensitivity to drug ...increased DNA methylation within BRCA1 promoter in ovarian cancer patients correlate with better platinum-based ... See full document
9
Harnessing the potential of epigenetic therapy to target solid tumors
... Targeting DNA methylation abnormalities in cancer involves the protein complexes that regulate and functionally interact with methylated DNA (Figure ...2). DNA methylation in ... See full document
9
The landscape of DNA methylation associated with the transcriptomic network in layers and broilers generates insight into embryonic muscle development in chicken
... by DNA methylation at the second muscle developmental ...different development between the layers and the ...low methylation may be responsible for fast muscle ...higher methylation ... See full document
15
The Impression of Histone Modification and DNA Methylation in Gastric Cancer Development: Molecular Mechanism Approach
... DNA methylation is a notable and vital regulator of gene expression and may occur as hypo or hypermethylation ...(4).The methylation of the 5- carbon on cytosine in CpG dinucleotides was the first ... See full document
9
Interplay between DNA methylation, histone modification and chromatin remodeling in stem cells and during development
... H3K4 methylation levels together with an increased DNA methy- lation level in a mouse embryonic fibroblast cells (Milne et ...increased DNA methylation levels in the Hox d4 gene ... See full document
13
Insufficient maintenance DNA methylation is associated with abnormal embryonic development
... maintenance DNA methylation plays an important role in the pathogenesis of ...a DNA methylation inhibitor presented typical symptoms of EPL with low implantation and pregnancy rates, and the ... See full document
10
Epigenomic analysis of lung adenocarcinoma reveals novel DNA methylation patterns associated with smoking
... lung cancer often demonstrates clinical and pathologic characteristics different from lung cancers that are not associated with ...lung cancer and nonsmoking lung ...specific DNA methylation ... See full document
9
DNA Methylation in Colorectal Cancer: A brief Review
... particularly DNA methylation in specific gene promoters, are recognized as common molecular ...mechanisms, DNA methylation acts to regulate gene expression and facilitate chromatin ... See full document
7
Original Article Semaphorin-3F functions as a tumor suppressor in colorectal cancer due to regulation by DNA methylation
... unclear. DNA methylation plays an important role in ...island methylation of tumor suppressor gene resulted in inactivation of the gene transcription has become an important part of cancer ... See full document
9
Exploring The Role Of Tet1 In Genomic Imprinting
... of DNA methylation and simultaneous protection from demethylation after ...imprinted DNA methylation at the H19 (Table ...of DNA methylation at a subset of ICRs (Nakamura et ... See full document
153
Role of DNA methylation in head and neck cancer
... neck cancer (HNC) is a highly heterogenous group of malignant diseases and the sixth most frequently observed cancer type in developing countries (Crowe et ...larynx cancer (Ohshima et ...of ... See full document
28
Vitamin D, DNA methylation, and breast cancer
... breast cancer (852 cases, 1026 from subcohort, including 41 additional cases): ratio of hazard ratios and 95% confidence ...and methylation on the 5-year risk of postmenopausal breast cancer (852 ... See full document
11
BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1tumour phenotype
... some methylation in this region, com- monly at -37 and -29 in peripheral blood in individuals with and without breast cancer ...observed methylation in only three individuals using both MS-HRM and ... See full document
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