[PDF] Top 20 Does simvastatin stimulate bone formation in vivo?
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Does simvastatin stimulate bone formation in vivo?
... Reverse-phase high performance liquid chromatography (RP-HPLC) tandem electrospray ionization mass spec- trometry (ESI-MS) method published by Wu et al. [15] was used to analyze samples of mouse serum for the pres- ence ... See full document
10
Human breast cancer bone metastasis in vitro and in vivo: a novel 3D model system for studies of tumour cell-bone cell interactions.
... turn stimulate growth of the tumour cells (21). Following in vivo implantation but prior to neovascularisation of the human bone, the levels of bone formation and human haematopoiesis ... See full document
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Pathways to Equity: An Auto-Ethnographic and Narrative Study of Teacher Educator and Preservice Teachers in a One-Credit Course and Community-Based Field Experience
... activity does not appear to be an essential component of the varied response of ADSCs in hypoxic ...conditions. Bone formation in vivo requires a coupling of osteogenesis and angiogenesis, ... See full document
129
The possibility of healing alveolar bone defects with simvastatin thermosensitive gel: in vitro/in vivo evaluation
... vivo and in vitro research found that statins activate osteoblast and promote bone formation. This research used sustainedly released in situ gel containing SVT as the functional delivery system to ... See full document
7
Using poly(lactic-co-glycolic acid) microspheres to encapsulate plasmid of bone morphogenetic protein 2/polyethylenimine nanoparticles to promote bone formation in vitro and in vivo
... cells, stimulate its differentiation, matrix mineralization, and bone ...new bone in vivo at 8 weeks post-implantation with a gelatin sponge impregnated with PLGA@pBMP-2/ PEI (Figures 6 and ... See full document
11
EMD273316 & EMD95833, type 4 phosphodiesterase inhibitors, stimulate fibroblastic-colony formation by bone marrow cells via direct inhibition of PDE4 and the induction of endogenous prostaglandin synthesis
... to stimulate bone for- mation in vitro and in vivo and have been suggested as possible antiosteoporotic drugs ...to stimulate the recruit- ment of osteoprogenitors from bone marrow in ... See full document
10
Oxygen derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo
... with bone particles, to which they attach. We confirmed the formation of superoxide anion in isolated avian osteoclasts using ferricytochrome c reduction as a method of ... See full document
9
In vitro and in vivo studies of surface-structured implants for bone formation
... stimulated bone growth and accelerated formation of the bone-implant ...interfacial formation and decreasing implant success due to the instability of the bone-implant ... See full document
9
Mechanical signals promote osteogenic fate through a primary cilia mediated mechanism
... in bone formation rates for both our control and experimental animals, we used dynamic histomorphometry to visualize areas of active bone formation ...induced bone formation, we ... See full document
23
Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro
... Inhibitors of the proteasome have been used recent- ly to probe the role of intracellular proteolytic degra- dation in specific cellular processes and more recently as potential therapies in certain cancers (4). Recent ... See full document
13
Combination of simvastatin and hydroxyapatite fiber induces bone augmentation
... the bone formation by blending ...of simvastatin from HAF was calculated per 24 hours for 10 ...containing simvastatin (0, ...new bone volume ratio measured by Micro-CT of 4 and 8 weeks ... See full document
8
Influence of osteogenic stimulation and VEGF treatment on in vivo bone formation in hMSC seeded cancellous bone scaffolds
... In the 12 weeks group, further ingrowth of the surround- ing tissue into the constructs occurred. Especially, a change in the vascularization and the appearance of bigger fat cell aggregations was noticeable in all ... See full document
10
Investigation of changes in bone density and chemical composition associated with bone marrow oedema type appearances in magnetic resonance images of the equine forelimb
... Following analysis of the individual-location spectra, data were averaged over specific regions of interest within the sample slices. Location names are given such that anterior would correlate to the dorsal location in ... See full document
10
Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells
... human bone marrow-derived stromal cells (hBMSC)) are adult multi- potent stem cells located in the bone marrow perivascu- lar niche and are recruited to bone formation sites during bone ... See full document
14
Effects of Bone Marrow Mesenchymal Stem Cells-Conditioned Medium on Tibial Partial Osteotomy Model of Fracture Healing in Hypothyroidism Rats
... and bone formation [35-37] . However, formation of blood vessels plays a key role in bone formation because blood vessels can transport oxygen, soluble growth factors, nutrients, and ... See full document
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“Fabrication and Evaluation of Solid Dispersion Containing Simvastatin” by D.V. Gowda, Rohan D. Deshpande, Keerthy H.S, Vishnu Datta, India.
... he term solid dispersion refers to a group of solid products consisting of at least two different components, generally a hydrophilic matrix and a hydrophobic drug. The matrix can be either crystalline or amorphous. The ... See full document
5
Tissue engineering scaled up, anatomically shaped osteochondral constructs for joint resurfacing
... The first objective of the study was to determine the combination of cell and scaffold type that could be used to tissue-engineer phenotypically stable cartilage overlaying functional bone in vivo (Fig. 1). ... See full document
24
Does intellectual monopoly stimulate or stifle innovation?
... Given that quality improvement and variety expansion are both important channels for economic growth, the growth-maximizing pro…t-division rule should balance between the asymmetric e¤ec[r] ... See full document
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Effects of simvastatin on apolipoprotein M in vivo and in vitro
... The human hepatoblastoma cell line, HepG2, was obtained from the American Type Culture Collection (ATCC, Manassas, VA). Male Swiss mice were pur- chased from Shanghai Slac Laboratory Animal Co. (Shanghai, China). ... See full document
6
Osteoporosis: A "New Morbidity" for Dieting Female Adolescents?
... Although the net effect on BMD is reduction, does anorexia nervosa result in decreased bone formation, increased bone resorption, or a combi- nation. Only studies that measure bone forma[r] ... See full document
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