[PDF] Top 20 Early goal-directed resuscitation for patients with severe sepsis and septic shock: a meta-analysis and trial sequential analysis
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Early goal-directed resuscitation for patients with severe sepsis and septic shock: a meta-analysis and trial sequential analysis
... fluid resuscitation therapy under the guidance of lactate concentration rate was feas- ible and reliable in patients with severe sepsis and septic shock ...that early ... See full document
12
Comparison of the effects of albumin and crystalloid on mortality in adult patients with severe sepsis and septic shock: a meta analysis of randomized clinical trials
... the resuscitation of adult patients with severe sepsis and septic shock compared with crystalloid by ...adult patients with severe sepsis and septic ... See full document
8
The effects and safety of vasopressin receptor agonists in patients with septic shock: a meta analysis and trial sequential analysis
... the trial sequen- tial analysis (TSA) to decrease the risks of random er- rors due to sparse data and repetitive testing and calculate the optimal information size for this ...the ... See full document
11
Early goal directed resuscitation of patients with septic shock: current evidence and future directions
... Severe sepsis and septic shock are among the leading causes of mortality in the intensive care ...ago, early goal-directed therapy (EGDT) emerged as a novel approach for ... See full document
10
Review Article Variable efficacy of drotrecogin alfa (activated) in severe sepsis and septic shock: a meta-analysis
... during sepsis be- cause of the down regulation of thrombomodu- lin by the inflammatory ...of patients with sepsis, and are associated with an increased risk of death ...of severe sepsis ... See full document
10
The clinical efficacy of intravenous IgM-enriched immunoglobulin (pentaglobin) in sepsis or septic shock: a meta-analysis with trial sequential analysis
... surviving sepsis campaign (SSC) approach, including early eradication of septic foci, administration of anti-infective agents, and maintenance of hemodynamic stability through fluid administration ... See full document
14
<p>Septic shock in the ER: diagnostic and management challenges</p>
... in Severe Sepsis (VISEP) trial 95 had to stop early due to a trend of increased 90-day mortality ...for Severe Sepsis/Septic Shock (6S) trial compared the ... See full document
10
Review Article Early actate levelsfor prediction of mortality in patients with sepsis or septic shock: a meta-analysis
... studies: septic shock, severe sepsis or septic shock, severe sepsis, HIV Type 1-Infected and severe sepsis, sepsis and circulatory failure, ... See full document
11
Is early ventricular dysfunction or dilatation associated with lower mortality rate in adult severe sepsis and septic shock? A meta analysis
... Considering the challenges above, we suggest future studies should be prospective in nature and use the Consensus definition for recruitment. To improve gen- eralizability, exclusion criteria should not be too restric- ... See full document
13
Early goal-directed therapy in the management of severe sepsis or septic shock in adults: a meta-analysis of randomized controlled trials
... and early lactate clearance may be more effective for severe sepsis or septic shock than EGDT in the present ...that early lactate-guided therapy significantly reduced hospital ... See full document
12
Echocardiogram-guided resuscitation versus early goal-directed therapy in the treatment of septic shock: a randomized, controlled, feasibility trial
... our trial, a median of 3 L or 35 mL/kg, was higher than other recent major trials of early sepsis ...PRISM trial, a patient-level meta-analysis of all patients enrolled in ... See full document
8
Early goal directed therapy in severe sepsis and septic shock: insights and comparisons to ProCESS, ProMISe, and ARISE
... for early management of severe sepsis and septic shock in the emergency ...called early goal-directed therapy was compared to standard care and this clinical ... See full document
16
One year mortality of patients treated with an emergency department based early goal directed therapy protocol for severe sepsis and septic shock: a before and after study
... 14%). Patients with end-stage renal disease who develop sepsis have been shown to have a higher mortality compared with the general population ...which meta-analytic data have been suggested to have ... See full document
7
Predicting 30 day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics
... of time to antibiotics on survival in patients with severe sepsis or septic shock in.. whom early goal-directed therapy was initiated in the emergency department.[r] ... See full document
18
Effects of crystalloids and colloids on liver and intestine microcirculation and function in cecal ligation and puncture induced septic rodents
... for Severe Sepsis/Septic Shock (6S) trial, patients in the HES group received almost the same amount of volume when compared with patients in the RA group to achieve ... See full document
11
Success of applying early goal-directed therapy for septic shock patients in the emergency department
... Methods: This was a prospective observational study in an emergency room setting at a tertiary care facility where EGDT was applied for resuscitation of severe sepsis and septic shock ... See full document
6
Sepsis-3 definitions predict ICU mortality in a low–middle-income country
... new sepsis definitions raised several concerns [26, 27], and the Surviving Sepsis Campaign suggested that lactate should continue to be measured to identify dysfunction ...of Sepsis-3 definitions, ... See full document
9
Conservative fluid therapy in septic shock: an example of targeted therapeutic minimization
... of sepsis care bundles in adults (aged ≥ 18 years) using these search terms: sepsis, septic shock, treatment, guidelines, protocols, GDT, and bundles (Figure ...enroll septic ... See full document
8
Fluid resuscitation therapy in endotoxemic hamsters improves survival and attenuates capillary perfusion deficits and inflammatory responses by a mechanism related to nitric oxide
... and patients specific- ities may determine heterogeneous endothelium dys- ...function. Patients with systemic chronic comorbidities, long lasting diseases, or malnourished ones may have al- terations of the ... See full document
13
Is Left Ventricular Global Longitudinal Strain by Two-Dimensional Speckle Tracking Echocardiography in Sepsis Cardiomyopathy ready for prime time use in the ICU?
... studies that included 794 patients with severe sepsis and/or septic shock. 81[r] ... See full document
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