[PDF] Top 20 Effect of Cell Polarization on Hepatitis C Virus Entry
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Effect of Cell Polarization on Hepatitis C Virus Entry
... for hepatitis C virus (HCV) replication in vivo is believed to be hepatocytes within the ...host cell molecules have been reported to be important entry factors for receptors for HCV: ... See full document
10
Human Serum Amyloid A Protein Inhibits Hepatitis C Virus Entry into Cells
... HCV entry but does not affect virus ...inhibitory effect on HCV in- fectivity could be to its ability to block the SR-BI receptor/ ...HCV entry. Huh7.5 cells were infected with HCV at ... See full document
6
Cell Death-Inducing DFFA-Like Effector b Is Required for Hepatitis C Virus Entry into Hepatocytes
... inhibitory effect of CIDEB shRNA in ...a C-terminal domain deletion partially rescued HCV infection ...KD cell lines ...stem cell-de- rived DHH/HLCs and Huh-7.5 cells and that the ... See full document
12
Epithelial cell polarization is a determinant in the infectious outcome of immunoglobulin A-mediated entry by Epstein-Barr virus.
... Epstein-Barr virus (EBV) infection typically occur in chronic virus carriers with preexisting virus-specific ...the effect on viral antigen ...basal cell face into apical medium without ... See full document
8
Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action
... the virus. A morphological effect of EGCG on herpes simplex virus particles was previously described (37) in which destruction of the viral envelope was observed, probably because of the interaction ... See full document
11
Sulfated Homologues of Heparin Inhibit Hepatitis C Virus Entry into Mammalian Cells
... of cell surface-expressed heparan sulfate to analyze HCV glycoprotein ...inhibitory effect of heparin or its derivatives at lower concentrations could be due to a lower level of incorporation of the natural ... See full document
9
CD81 and Claudin 1 Coreceptor Association: Role in Hepatitis C Virus Entry
... various cell types demonstrate protein association, consistent with the for- mation of coreceptor ...between cell-surface- expressed ...HCV entry. This is in contrast to a recent report by Yang and ... See full document
14
Hepatitis C Virus Entry Depends on Clathrin-Mediated Endocytosis
... HCVpp entry is clathrin dependent. The pH dependency of HCVpp entry implies that HCVpp fusion does not occur at the plasma membrane but from within an intracellular acidic com- partment, most probably an ... See full document
9
Flavonoids from Pterogyne nitens Inhibit Hepatitis C Virus Entry
... Hepatitis C virus (HCV) is one of the leading causes of liver diseases and transplantation ...infectious virus systems. Flavonoids 1 and 2 inhibited virus entry up to ...to ... See full document
9
Protein Kinase A-Dependent Step(s) in Hepatitis C Virus Entry and Infectivity
... Inhibition of PKA activity induces a reorganization of CLDN1 in Huh-7.5 cells. HCV utilizes the cellular molecules CD81, SR-BI, and CLDN1 to enter target cells. To investigate whether the inhibitory activity of H89 ... See full document
15
Pim Kinase Interacts with Nonstructural 5A Protein and Regulates Hepatitis C Virus Entry
... including cell cycle, cell survival, apoptosis, and signal transduction pathways ...little effect on HCV propagation, whereas knockdown of all Pim proteins im- paired HCV ... See full document
14
Screening and Rational Design of Hepatitis C Virus Entry Inhibitory Peptides Derived from GB Virus A NS5A
... by hepatitis C virus (HCV) is a cause of the global burden of liver ...HCV entry into hepatocytes is a complicated and multistep process that represents a promising target for antiviral ...GB ... See full document
9
Polarization Restricts Hepatitis C Virus Entry into HepG2 Hepatoma Cells
... in cell permeability contribute to a wide range of pathological conditions, including inflam- matory bowel disease, cystic fibrosis, and perturbation of the blood-brain barrier (reviewed in reference ...model ... See full document
11
New Insights into the Understanding of Hepatitis C Virus Entry and Cell-to-Cell Transmission by Using the Ionophore Monensin A
... HCV cell-to-cell transmission is a pH-dependent ...to cell-free infection, HCV can also propagate by cell-to-cell ...Since cell-to-cell transmission has been suggested to ... See full document
19
Inhibitory effect of kaolin minerals compound against hepatitis C virus in Huh 7 cell lines
... We suggest that there could be excellent therapeutic agents in kaolin mineral compounds for the treatment of HCV infections. However, further studies are re- quired to identify the specific active ingredients by using ... See full document
5
Identification of Novel Functions for Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly
... HCV cell entry process as a modulator of entry factor ...host cell entry (21, 38–40), so a change in receptor dependence from CLDN1 to CLDN6 is not entirely ... See full document
19
Inhibition of Hepatitis C Virus 3a genotype entry through Glanthus Nivalis Agglutinin
... HCV virus of genotype 3a in each well were performed after washing twice with 1X ...(minimum cell killing) in the remaining five wells on the same day for checking the antiviral response of ...with ... See full document
7
An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry
... The hepatitis C virus (HCV) envelope glycoprotein E2 is the major target of broadly neutralizing antibodies in vivo and is the focus of efforts in the rational design of a universal B cell ... See full document
18
Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission
... nAb-resistant cell-to-cell transmission is CD81 ...that cell-free virus infectivity is sensitive to the neutralizing effect(s) of antibodies targeting the viral glycopro- teins ... See full document
10
Sec24C-Dependent Transport of Claudin-1 Regulates Hepatitis C Virus Entry
... GST. Cell lysates from ...components. Cell lysates from ...(C) Cell lysates from ...h. Cell lysates were incubated with anti-Flag antibody-coated beads, and co-IP proteins were ... See full document
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