[PDF] Top 20 The effect of immune responses in HCV disease progression
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The effect of immune responses in HCV disease progression
... HCV considering four population susceptible or healthy liver cell, infected liver cell, virus, and CTL responses. Zhao et al. [8] assume that the incidence rate of the virus model is described by a ... See full document
14
The Effect of Smoke Cigarette on Immune Responses of Allergic Rhinitis Patients
... different effect of cigarette smoking on immune ...pathological effect on different immune system of allergic rhinitis patients is not well ...the effect of cigarette smoking on ... See full document
6
Immune Responses to HSP65/60 in Periodontal Disease
... dulating effect on humoral immune responses to HSP [16] and instrumentation may immunise patients with plaque ...confounding effect of treat- ment in our results we recruited untreated ... See full document
7
Serologic and mucosal immune response to rotavirus infection in the rabbit model.
... Future uses of the model include studies to examine the immune response to individual rotavirus proteins, the effect of preexisting antibody on immune responses, the effect of virus dose[r] ... See full document
10
The Wild-Type Hepatitis C Virus Core Inhibits Initiation of Antigen-Specific T- and B-Cell Immune Responses in BALB/c Mice
... cell-mediated immune responses induced by full-length or truncated HCV core proteins were assessed by ELISPOT assays, using peptides corresponding to the HCV core-specific epitope at aa 39 to ... See full document
9
An overview of HCV molecular biology, replication and immune responses
... chronic HCV infection (defined as infec- tion persisting over more than six months with positive HCV-antibody and HCV-RNA detectable in the serum) are candidates for ...innate immune ... See full document
10
High, Broad, Polyfunctional, and Durable T Cell Immune Responses Induced in Mice by a Novel Hepatitis C Virus (HCV) Vaccine Candidate (MVA-HCV) Based on Modified Vaccinia Virus Ankara Expressing the Nearly Full-Length HCV Genome
... by HCV to subvert the host innate immune response is to undermine IFN antiviral activ- ity, as well as functions of innate immune ...of HCV are represented by the PAMP signaling pathways, ... See full document
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The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
... beneficial effect, probably via the same inflammatory ...inflammatory responses, in which ligands are pres- ent only ...human disease, it does suggest a way in which RAGE-mediated processes can be ... See full document
8
Cellular Immune Responses in Seronegative Sexual Contacts of Acute Hepatitis C Patients
... liver disease, leading to chronic infection in as many as 170 million persons ...for HCV, like that for hu- man immunodeficiency virus type 1 (HIV-1), is limited by the quasispecies nature of the virus as ... See full document
7
Sequential Priming with Simian Immunodeficiency Virus (SIV) DNA Vaccines, with or without Encoded Cytokines, and a Replicating Adenovirus-SIV Recombinant Followed by Protein Boosting Does Not Control a Pathogenic SIVmac251 Mucosal Challenge
... IL-15 may enhance central memory cells, while IL-12 may lead to greater terminal differentiation and development of effector memory cells (1). In nonhuman primates, IL-15 enhances both CD4 and CD8 effector memory T cells ... See full document
11
Longitudinal Analysis of Prototheca zopfii Specific Immune Responses: Correlation with Disease Progression and Carriage in Dairy Cows
... cellular immune responses to bovine mammary protothecosis, serum and whey samples obtained from 72 dairy cows assigned to four different clinical stages of infection were examined for specific antibodies by ... See full document
6
High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease
... of HCV quasispecies would decrease in late stage disease due to a reduced immune response, while the more active immune responses in the earlier phases of infection may select for a ... See full document
11
Cellular immune response to hepatitis-C-virus in subjects without viremia or seroconversion: is it important?
... Although HCV-specific T-cells can be more numerous in the peripheral blood mononuclear cells (PBMCs) of chronic patients than in recovered subjects, the T-cells in chronic subjects display a reduced proliferative ... See full document
12
Progression of Fibrosis during Chronic Hepatitis C Is Associated with Rapid Virus Evolution
... of HCV infection and fibrosis progression (51), we identified case subjects (fast pro- gressors [FP]) with little or no fibrosis on initial liver biopsy followed by rapid progression of fibrosis 4 ... See full document
10
Immune Responses and Viral Replication in Long-Term Inapparent Carrier Ponies Inoculated with Equine Infectious Anemia Virus
... of immune maturation to persistent EIAV infection, they do not appear to define specific immune properties that correlate with the de- velopment of immune control of virus replication and ... See full document
14
Factors Associated with Slow Disease Progression in Macaques Immunized with an Adenovirus-Simian Immunodeficiency Virus (SIV) Envelope Priming-gp120 Boosting Regimen and Challenged Vaginally with SIVmac251
... long-lasting effect on the eventual disease outcome, we moni- tored the animals over the next 140 ...protective responses were investigated, and the results are reported ... See full document
12
The monoclonal antibody to cytotoxic T lymphocyte antigen 4, ipilimumab, in the treatment of melanoma
... the effect of this immunotherapy takes many weeks to ...efficacy. Responses can occur later and may be more durable with ipilimumab than with traditional ...The immune response generated in the first ... See full document
8
Reduction of Simian-Human Immunodeficiency Virus 89.6P Viremia in Rhesus Monkeys by Recombinant Modified Vaccinia Virus Ankara Vaccination
... eliciting immune responses, controlling viremia, and preventing clinical se- quelae of an AIDS virus ...primed immune response with a recombinant live vector (2, 15, 19, ...slowed disease ... See full document
8
The Role of Regulatory T Cells during Feline Immunodeficiency Virus Pathogenesis
... HIV-1 disease progression, including antiviral responses, immune activation, CD4 + T cell levels, and viral load have implicated Treg cells as regulators of the immune response to HIV-1 ... See full document
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Preventing transfusion-associated graft-versus-host disease: state of the art
... phocyte responses to antigens expressed by the recipient ...strong responses to human cells, causing their elimination, xenogeneic GVHD has only been observed in immunodeficient mice, with the more ... See full document
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