[PDF] Top 20 Effect of low tidal volume ventilation on lung function and inflammation in mice
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Effect of low tidal volume ventilation on lung function and inflammation in mice
... study low tidal volumes were associated with very low oxygen saturation during mechanical venti- ...small tidal volumes (5 and 7 ml/kg) did not recruit sufficient alveolar units for adequate ... See full document
8
Intravenous superoxide dismutase as a protective agent to prevent impairment of lung function induced by high tidal volume ventilation
... h ventilation with (A) low tidal volume (LTV; 8 mL/kg; n = 10), (B) high tidal volume (HTV; 18 mL/kg; n = 14), or (C) HTV and intravenous treatment of Cu/Zn SOD at a dose of 1000 ... See full document
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Open lung approach associated with high frequency oscillatory or low tidal volume mechanical ventilation improves respiratory function and minimizes lung injury in healthy and injured rats
... A total of 78 specific pathogen-free male Wistar rats (450-500 g) housed in standard condition with food and water given ad libitum were anesthetized by intraperito- neal (IP) injection of ketamine hydrochloride (50 ... See full document
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Cardiac index and oxygen delivery during low and high tidal volume ventilation strategies in patients with acute respiratory distress syndrome: a crossover randomized clinical trial
... the ventilation-perfusion mismatch, a well-recognized cause of hypoxemia in ARDS patients ...First, low TV compared to high TV strategy increases spontaneous respiratory activity improving ... See full document
9
Injurious mechanical ventilation in the normal lung causes a progressive pathologic change in dynamic alveolar mechanics
... large volume change deactivates pulmonary surfactant [12-17,22,24,26], which would cause alveoli to become unstable ...high tidal volume and low PEEP had altered surfactant composition, with a ... See full document
9
Original Article Protective effects of low tidal volume mechanical ventilation associated with WISP1 -TRL4 signaling pathway in a sepsis model of mice
... and lung infection (RR ...protective ventilation did not affect atelecta- sis (RR ...beneficial effect of low tidal volume ventilation by Wolthuis et al [21] and ... See full document
13
Management of primary blast lung injury: a comparison of airway pressure release versus low tidal volume ventilation
... eous ventilation, evolving acute lung injury including non-cardiogenic pulmonary oedema as well as ventilator-induced lung injury ...blast lung injury in a large animal model ... See full document
11
The effects of low tidal ventilation on lung strain correlate with respiratory system compliance
... same tidal volume ventilation con- ...recruitable lung compared with those with lower amounts of recruitable lung under similar tidal volume application conditions ... See full document
9
Unfractionated heparin and enoxaparin reduce high stretch ventilation augmented lung injury: a prospective, controlled animal experiment
... in lung epithelial cells triggered by TGF-β1 ...high tidal volume increased lung inflammation demonstrated by changes of microvascular per- meability, lung edema, neutrophil ... See full document
12
Re inspiration of CO2 from ventilator circuit: effects of circuit flushing and aspiration of dead space up to high respiratory rate
... obstructive lung disease, and at increased intracranial pressure it may be important to maintain adequate CO 2 exchange at low tidal volume ventilation ...of tidal volume ... See full document
8
Driving pressure and long-term outcomes in moderate/severe acute respiratory distress syndrome
... mechanical ventilation, the “ARDSnet Protocol versus Open Lung Approach in ARDS” trial (NCT 00431158) ...uses low tidal volumes, relatively high respiratory rates, with oxygenation managed ... See full document
10
Sevoflurane attenuates pulmonary inflammation and ventilator-induced lung injury by upregulation of HO-1 mRNA expression in mice
... healthy mice were divided into four groups, each consisting of ten subjects: mice in group Con-L VT and group Sev-L VT were ventilated with tidal volumes of 8 mL/kg for 4 hours, while those in group ... See full document
7
RIPK3 mediates pathogenesis of experimental ventilator-induced lung injury
... in mice and exposure to mechanical ...(A) lung elas- tance were recorded, and bronchoalveolar lavage fluid (BALF) was measured for (B) total protein concentration and (C) lactate dehydrogenase (LDH) in WT ... See full document
13
Open lung approach with low tidal volume mechanical ventilation attenuates lung injury in rats with massive brain damage
... to inflammation and edema. High volume at end-inspiration is well known to promote alveolar distension, disruption of pulmonary epithelium and endothelium, recruitment of pro-inflammatory cells in the ... See full document
10
Effects of frequency, tidal volume, and lung volume on CO2 elimination in dogs by high frequency (2 30 Hz), low tidal volume ventilation
... monotonically with f at constant VT. We quantitated the effects of f and VT on VCO2 by using the dimensionless equation VCO2/VOSC = a(VT/VTo)b(f/fo)c where: VOSC = f X VT, VTo = mean VT, fo = mean f and a, b, c, are ... See full document
11
Original Article The assessment of the effect of low tidal volume ventilation on postoperative respiratory functions during cardiopulmonary bypass in heart surgery
... mechanical ventilation meth- ods can decrease both pulmonary dysfunction and inflammation which occur during cardiac ...open lung approach. The open lung approach, which is applied by ... See full document
8
Mechanical ventilation with high tidal volume induces inflammation in patients without lung disease
... Mechanical ventilation (MV) with high tidal volumes may induce or aggravate lung injury in critical ill ...and lung production of tumor necrosis factor-a (TNF-a) and interleukin-8 (IL-8) in ... See full document
9
High Frequency Ventilation for Immature Infants
... Slutaky AS, Drazen JM, Ingram RH Jr, et al: CO2 elimina- tion in dogs by high frequency (3-30 Hz), low tidal volume ventilation: Effect of frequency, tidal volume and lung vol- ume. Flet[r] ... See full document
10
A ventilator strategy combining low tidal volume ventilation, recruitment maneuvers, and high positive end-expiratory pressure does not increase sedative, opioid, or neuromuscular blocker use in adults with acute respiratory distress syndrome and may improve patient comfort
... While low tidal volume ventilation is a standard of care in the management of adult ARDS, the role for higher ver- sus lower PEEP strategies is less ...acute lung injury ...high-PEEP ... See full document
8
Lung ventilation during treadmill locomotion in a terrestrial turtle, Terrapene carolina
... simultaneous ventilation and locomotion because axial muscles are used in a unilateral activation pattern to bend the body from side to side during locomotion, while many of those same muscles require a ... See full document
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