[PDF] Top 20 Effectiveness of tranexamic acid in reducing blood loss in spinal surgery: a meta analysis

... of blood transfusion and DVT or other thromboembolism, partial thromboplastic time (PTT), thromboembolic complications, and any other outcomes as mentioned in included ...total blood loss and the ... See full document

... current meta-analysis demonstrated that TXA plus DEP has a beneficial effect on total blood ...total blood loss by 209.79 ml than TXA alone. Several meta-analyses have found that ... See full document

... able blood loss, and transfusion carries a sub- stantial risk of immunologic reaction and trans- mission of disease [3, ...postoperative blood loss and avoid homolo- gous blood ... See full document

... (AIS) surgery usually require prolonged operative times with extensive soft tissue dissection and significant perioperative blood loss, and allogeneic blood products are frequently ...of ... See full document

... hidden blood loss for the two groups, and Aguilera [24] favors the use of topical administration to reduce hid- den blood loss after TKA, whereas Hou and col- leagues [47] found no difference ... See full document

... This meta-analysis aimed to explore the opti- mal hemostasis agent for ...in reducing the need for transfusion than fibrin tissue ...total blood loss, fibrin tissue adhesive was ... See full document

... mic acid use on reducing intraoperative blood loss and transfusion needs in complex spine ...of surgery was 448 min, the numbers of levels fused 7.6 and the total blood ... See full document

... Tranexamic acid (TXA), an antifibrinolytic drug, com- petitively blocks the lysine-binding site of plasminogen and has been used to reduce blood loss in spine surgery for many years ... See full document

... that tranexamic acid was used in spinal tuberculosis surgery and achieved good hemostatic effects ...[15]. Tranexamic acid can combine with plasmino- gen and lysine binding site ... See full document

... the meta-analysis if: 1) patients underwent primary unilateral TKA or THA; 2) the study involved the comparison of a TXA treatment group to a control group who received either a placebo or no treat- ment at ... See full document

... cumulative meta-analysis showed reliable evidence that TA reduces the need for ...on blood loss varies with the extent of surgical ...of blood loss between procedures and the ... See full document

... decrease blood loss and transfusion rates without increasing the risk of ...previous meta- analysis was performed, the meta-analysis included a limited number of studies, and the ... See full document

... in reducing transfusion risks and costs ...in reducing peri-operative blood loss and transfusion ...orthopaedic surgery, and even fewer compare the two drugs head to head in large ... See full document

... fusion surgery is the most com- mon surgical treatment for degenerative lum- bar spinal ...significant blood loss [1]. Excessive blood loss could result in anemia and coagu- ... See full document

... The meta-analysis of Sun et ...regarding blood loss, hemoglobin decline, and transfusion ...allogeneic blood transfusion and blood loss in PLF ... See full document

... total blood loss in total joint arthroplasty [30, 31]. Due to the blood loss may leading to postoperative hypoxemia, the blood transfusion is ...However, blood transfusion is ... See full document

... pregnancy induced hypertension (PIH), intrauterine growth retardation (IUGR),premature rupture of membrane (PROM).There was also no significant difference with regards to poor obstetric history and indications of LSCS ... See full document

... Tranexamic acid (TXA) has an antifibrinolytic effect through inhibition of plasminogen activator that helps in the conversion of plasminogen to ...reduce blood loss in elective surgery ... See full document

... postoperative blood loss and knee swelling in conventional TKR (Con-TKR); however, there still has been no guideline for using of IA-TXA such as the dosage of TXA which varied from 500 mg to 3,000 mg, using ... See full document

... All the TKAs were performed using the midline skin in- cision and medial parapatellar approach. A measured re- section technique was used in the surgery. The tourniquet was utilized in all patients which was ... See full document