[PDF] Top 20 Effects of Single P-Element Insertions on Olfactory Behavior in Drosophila melanogaster

... This is demon- strated clearly in the accompanying paper where it is used to analyze effects of P-element insertions on bristle number and viability (LYMAN et al. Here, w[r] ... See full document

... To evaluate theoretical models of mutationselection balance, we require estimates of (1) the mutational vari- ance, (2) the number of loci at which spontaneous muta- tions [r] ... See full document

... adverse effects on odor-guided behavior are likely the consequence of early disruptions in the animal’s developmental ...aberrant olfactory behavior is a remnant of early developmental defects ... See full document

... a single concentration and that the response profiles shown in Figures 3 and 4 may shift at different odorant concentrations or with different Obp expression levels (Zhou et ... See full document

... long-term effects of exposure to specific microbes, flies were either exposed to the corresponding microbes for 2 days, or were continuously bred for several generations under these ... See full document

... odor-guided behavior in Drosophila. Previously, we identified a P-element insert line with generalized sexually dimorphic smell impairment, ...Wild-type behavior is restored by precise ... See full document

... disrupt single distinct ...gans, Drosophila melanogaster, Arabidopsis thaliana, Mus for gene-based approaches to biological ...1996), Drosophila (Cooley et ...mutagenic element must be ... See full document

... reciprocal crosses) to produce all possible 66 doubly heterozygous hybrids with P[lArB] insertions at two distinct locations. The olfactory behavior of the transheterozygous progeny was [r] ... See full document

... for P-element insertions for a given genomic genes without previous knowledge of a phenotype have region, it is equally desirable to generate a maximum been ...new P-element ... See full document

... situated insertions are grouped and represented by open triangles with the line numbers (see Tables 1 and 2 for map ...vector, P{GS}, whereas other insertion lines have the unidirectional vector ... See full document

... of single-copy molecular-genetic entry points can greatly facilitate structure and sequence analysis of heterochromatic regions that are rich in repeated ...new P-element insertions into ... See full document

... D. melanogaster ent genetic conflicts, rather than a reserve of evolution- find evidence of numerous small, mainly additive effects ary ...mutational effects should provide a (Weber et ... See full document

... gous lethal chromosomes with large heterozygous ef- fects on bristle traits have been recovered commonly from long-term Drosophila bristle selection lines, where they caus[r] ... See full document

... unusual behavior of the X in spermatogene- scaffold due to their repetitive ...X insertions. collection of P insertions would greatly facilitate func- The failure to recover fertile X-autosome ... See full document

... In an attempt to identify mutations in the Drosophila synaptotagmin gene we have isolated many new rearrangements, point mutations and P element insertions in the 22F1-2; 23B1-2 [r] ... See full document

... Recessive mutations at the suppressor of sable [su(s)] locus in Drosophila melanogaster result in suppression of second site mutations caused by insertions of the mo[r] ... See full document

... of single recombinant lines. Mean phenotypic effects of high-low (solid line) and low-high (dashed line) single recombinants from Figure 1 are ...of single recombinant means (Table 2) divide ... See full document

... Odorants that pass through pores on the sensillum bind to ORs expressed on the dendrite of OSNs and induce an action potential, which can be monitored using the single sensillum recording (SSR) technique (Bestmann ... See full document

... Although P elements in particular may initially have large (and negative) effects and lead to ongoing muta- genesis upon first invasion of a Drosophila genome, selection readily leads to suppression ... See full document

... of the expected P(:R fragment patterns, using the four primers diagrammed i n the figures. The <:-D primer pair initially gives a fragment from the right end of the el[r] ... See full document