[PDF] Top 20 Endothelial Dysfunction in Systemic Lupus Erythematosus.

... Endothelial dysfunction appears when the normal functions of the endothelial cells (control of vascular tone and blood pressure, regulation of leucocytes traffic from the blood to the tissues, and ... See full document

... Systemic lupus erythematosus (SLE) is an inflammatory, autoimmune disorder with multi-organ ...pathogenesis. Endothelial dysfunction, which occurs early during atherosclerosis ... See full document

... Introduction: Accelerated atherosclerosis is one of the major causes of morbidity in patients with systemic lupus erythematosus (SLE). Endothelial dysfunction (ED) is considered an ... See full document

... In the current study, we made the novel observation that platelet activation was related to endothelial activation in patients with SLE. Platelet activation was associated with both elevated serum sVCAM-1 ... See full document

... to systemic inflammation, and to endothelial dysfunction (partly medi- ated by autoantibodies) ...underlying endothelial dysfunction are present from the early stages of the disease ... See full document

... and systemic lupus erythema- tosus (SLE) are complex autoimmune diseases with systemic inflammatory compromise, in which different organs are involved, such as kidney and joints, respectively ... See full document

... to endothelial dys- ...the endothelial dysfunction [7– ...EPC dysfunction promoting abnormal angiogenesis, boosted by an ex- cess of IL10 [7, ...on endothelial progenitor cells and ... See full document

... and endothelial cells, suggesting that these cells can represent a target of autoantibodies in the antiphospholipid antibody syndrome ...on endothelial cells [32,33], we evaluated anti-β2-GPI and anti-CL ... See full document

... suppressor-cell dysfunction in active systemic lupus erythematosus (SLE), we fractionated blood mononuclear cells into thymus-derived (T), bone marrow-derived (B), and monocyte-depleted ... See full document

... radioimmunoassay to study the ability of IgG from normal human sera and sera from patients with SLE to bind to endothelial cells. In this assay, cultured human umbilical venous endothelial cells were ... See full document

... FNAC of cervical lymph node was suggestive of granu- lomatous lymphadenopathy (Figure 2). Excisional biopsy of cervical lymph node on H & E staining showed intact capsule and lymph nodal architecture was partially ... See full document

... syndrome, lupus anticoagulant/ anti-cardiolipin antibodies [1] (note that the relationship between PH and the lupus anticoagulant is not reproducible [107]), increased risk of developing thrombotic ... See full document

... Circulating antibodies that could be responsible for the suppressor thymus-derived (T)-cell dysfunction in active systemic lupus erythematosus (SLE) were investigated. Sera from 14 active and ... See full document

... neurocognitive dysfunction; NPSLE: neuropsychiatric systemic lupus erythematosus; ROI: region of interest; SES: socioeconomic status; SFNR: signal-to-fluctuation noise ratio; SLE: ... See full document

... mitochondrial dysfunction causes fatigue; and explained the role of oxidative stress and genetic susceptibility as a cause of ...and systemic inflammation inducing mitochondrial damage which accounts for ... See full document

... specific lupus headache and the optimal approach to headache in SLE cases remains ...cognitive dysfunction, mood disorder, cerebrovascular disease, [23] seizures, polyneuropathy, [23] anxiety disorder, and ... See full document

... Factors that are highly expressed in serum from SLE pa- tients may also play a role in the regulation of MSC func- tion. Evidence shows that TNF- α could increase MSC migration and invasion via activation of the nuclear ... See full document

... Systemic lupus erythematosus (SLE) is an autoimmune disease in which organs and cells undergo damage mediated by tissue-binding autoantibodies and immune complexes 1 ...between systemic ... See full document

... In all sera studied, heating at 560 C for 30 minutes significantly reduced cryoprecipitation, and the addition of untreated normal human serum to heatinactivated SLE sera partially or co[r] ... See full document

... Antinuclear antibodies in systemic lupus erythematosus Med J Malaysia Vol 44 No 2 June 1989 Antinuclear antibodies in systemic lupus erythematosus K ¥ Fong, MBBS, M Med (Int Med) M L Boey, MBBS, M Med[.] ... See full document