[PDF] Top 20 Epstein-Barr virus (EBV) gene expression in EBV-positive peripheral T-cell lymphomas.

... Although the 209-bp product representing EBNA2 mRNA was readily detected in the cDNA preparation from the B95-8 lymphoid cell line, the spliced product representing the EBNA2 mRNA was no[r] ... See full document

... lymphoblastoid cell lines (LCL) 9007, 9009, 9011, 9022, 9028, 9037, 9049, 9050, 9060, 9074, and 9103 from the 10th International Histocompatibility Workshop panel and with known HLA types were used as allogeneic ... See full document

... regarding EBV lytic cycle replication and its association with B-cell lymphomas and ...LPDs. EBV latent genes are sufficient for transformation of B cells in vitro (6, 14, 17, 33), so lytic ... See full document

... Epstein-Barr virus (EBV)-negative Burkitt lymphomas (BLs) can be infected in vitro with prototype EBV strains to study how the virus may affect the phenotype of tumor ... See full document

... of EBV-infected T cells with an activated cytotoxic phenotype ...pancytopenia, peripheral lymphade- nopathy and high LDH levels ...acute EBV infection, or in the setting of chronic ... See full document

... CCA T-3⬘) and MECP2antisense (5⬘-ATT AAC GCG TCA GCG GCA ACG GCC T-3⬘); for DET1, DET1sense (5⬘-GAC GAG ATC TAG CCA GAG AGA GGA GTG AGG-3⬘) and DET1antisense (5⬘-GAC GAA GCT TGC CGT GCT TAT GAG CTA AAT ... See full document

... Here we demonstrate by in situ hybridization the presence of EBV DNA in every cell of the experimentally induced B-cell lymphomas of tamarins and report on the expression of EBV-encoded [r] ... See full document

... EBERs, EBV-related miRNAs and mRNAs, exosomes containing other pathogenic proteins have also been reported to promote EBV-related cancers such as the transcription factor Galectin-9 [24,87], Deoxyuridine ... See full document

... tumor cell lines or overexpression of L22 from transfected expression plasmids have shown EBER1 to cause a relocation of L22 protein in cells, but the mechanism by which this binding of EBER1 to L22 may ... See full document

... Tetracycline-regulated expression of EBNA2 in Akata ...induce EBV cycle, and EBV replication is generally presumed to exert deleterious effects on ...EBNA2 gene and the hygromycin resistance ... See full document

... lympoblastoid cell lines). These cell lines are established by exogenous EBV infection of B ...viral gene expression during latency, EBV reduces the number of viral proteins that ... See full document

... silence gene expression play an important role in cancer ...in gene regulation (18, 39, ...in EBV-positive BL cells (25, 47, ...B cell lymphoma through DNA hypermethylation ... See full document

... viral gene expression, and induce necrosis and apoptosis, in C18 NPC tumor ...cells. EBV encodes a variety of proteins that inhibit apoptosis, in- cluding the latent protein LMP-1 and the lytic bcl-2 ... See full document

... The EBV-in- fected lymphoma cells in this animal model were confirmed to express Oct-2 (data not ...shown). T-cell-mediated effects may also contribute to the low level of early lytic viral protein ... See full document

... ABSTRACT Epstein-Barr virus (EBV) is convincingly associated with gastric cancer, nasopharyngeal carcinoma, and certain lymphomas, but its role in other cancer types remains ...of ... See full document

... nodal Peripheral T-cell Lymphomas (PTCL) exposes interesting features such as T-cell marker downregulation and paradoxically, the presence of reactive, clustered large- sized ... See full document

... of EBV-associated ...of EBV genome-containing T-cell lym- ...in peripheral T-cell lymphomas (38, ...of T-cell lymphomas for our present ... See full document

... B95.8-converted lines on several different EBV-negative BL-cell backgrounds all showed detectable expression of the nuclear antigens EBNA1, EBNA2, and EBNA3 and of the latent membrane pr[r] ... See full document

... Named Gene- Filters (Research Genetics) in Microhyb hybridization solution (Research Ge- netics) plus 25 ␮g of poly(dA) (Research Genetics) and 5 ␮g of heat-denatured Cot-1 DNA ... See full document

... Sequence variations in functional domains of BARF1 Most amino acid mutations exhibited in the first 60 amino acids of BARF1 protein, where essential transforming domain (amino acids 1–54) [10] and 5 HLA-A*0201-re- ... See full document