[PDF] Top 20 Evaluation of protective immune responses induced by DNA vaccines encoding Toxoplasma gondii surface antigen 1 (SAG1) and 14 3 3 protein in BALB/c mice
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Evaluation of protective immune responses induced by DNA vaccines encoding Toxoplasma gondii surface antigen 1 (SAG1) and 14 3 3 protein in BALB/c mice
... with 1×10 4 tachyzoites of the virulent RH T. gondii in immunized BALB/c mice was observed in this study, as compared to the control ...all mice were dead and constructed ... See full document
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Induction of long lasting protective immunity against Toxoplasma gondii in BALB/c mice by recombinant surface antigen 1 protein encapsulated in poly (lactide co glycolide) microparticles
... maintain protective SAG1-specific humoral and cell-mediated immune responses for an extended period (10 weeks) to protect mice from ...T. gondii tachyzoite ...extend protective ... See full document
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Evaluation of Immunogenicity of Cocktail DNA Vaccine Contain¬ing Plasmids Encoding Complete GRA5, SAG1, and ROP2 Antigens of Toxoplasma gondii in BALB/C Mice
... of Toxoplasma have an important role in stimulation of the protective immune ...ROP2 antigen, expressed by tachyzoites, brad- yzoites, and sporozoites, are considered as candidates for ... See full document
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Construction, Expression and Preliminary Immunological Evaluation of a DNA Plasmid Encoding the GRA2 Protein of Toxoplasma gondii
... a DNA- based vaccine because such vaccines have been shown to elicit a potent, long-lasting humoral and cell-mediated immunity, as well as providing protection against viral, bacterial, and parasitic ...of ... See full document
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Research progress on surface antigen 1 (SAG1) of Toxoplasma gondii
... vector vaccines Live bacterial vaccine vectors have been extensively used to deliver and express heterologous vaccine antigens to protect against cancer and various infectious agents, in- cluding ...bacterial ... See full document
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Compound DNA vaccine encoding SAG1/ SAG3 with A2/B subunit of cholera toxin as a genetic adjuvant protects BALB/c mice against Toxoplasma gondii
... multivalent antigen gene was connected to the A 2 /B subunit of cholera ...stronger immune responses were induced by this vac- cine in BALB/c mice and even high levels of ... See full document
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Alpha galactosylceramide enhances protective immunity induced by DNA vaccine of the SAG5D gene of Toxoplasma gondii
... SAG5D protein was a posi- tive antigen like SAG1 ...cellular immune response against T. gondii in ...in mice injected by pEGFP-C1-SAG5D or α-GalCer/pEGFP-C1- SAG5D compared with control ... See full document
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Protective immunity against acute toxoplasmosis in BALB/c mice induced by a DNA vaccine encoding Toxoplasma gondii elongation factor 1 alpha
... T. gondii infection [62]. CD3 + CD4 + CD8 − is the surface marker of T helper (Th) cells that can participate in the adaptive immune responses, while CD3 + CD8 + CD4 − is expressed on ... See full document
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Induction of Protective Immune Responses by a Multiantigenic DNA Vaccine Encoding GRA7 and ROP1 of Toxoplasma gondii
... DISCUSSION DNA vaccination can protect animals and human beings against pathogenic microorganisms, particularly intracellular parasites ...study, BALB/c mice immunized intramuscu- larly with ... See full document
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DNA vaccination with a gene encoding Toxoplasma gondii GRA6 induces partial protection against toxoplasmosis in BALB/c mice
... Cellular immune response induced by DNA vaccination To evaluate anti-GRA6 immune cellular responses in the DNA-vaccinated mice, spleen cell suspensions were prepared from ... See full document
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Evaluation of Immune Responses in Mice after DNA Immunization with Putative Toxoplasma gondii Calcium-Dependent Protein Kinase 5
... from 3 randomly chosen mice in each group were collected to detect specific anti-CDPK5 antibodies by ...in mice immunized with pVAX- CDPK5 ...immunity induced by pVAX- CDPK5, the subclasses of ... See full document
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A Toxoplasma gondii vaccine encoding multistage antigens in conjunction with ubiquitin confers protective immunity to BALB/c mice against parasite infection
... (FCM). Protective efficacy was evaluated by challenging immunized mice with type I and type II ...the DNA vaccine had the advantage of inducing a stronger humoral response, whereas the ... See full document
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Protective Efficacy of a Toxoplasma gondii Rhoptry Protein 13 Plasmid DNA Vaccine in Mice
... Toxoplasma gondii is an obligate intracellular parasite infecting humans and other warm-blooded animals, resulting in serious public health problems and economic losses ...T. gondii invasion and host ... See full document
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Protective Immunity Induced by Toxoplasma gondii Rhoptry Protein 16 against Toxoplasmosis in Mice
... T. gondii strain ...Inactivated vaccines are typically safer, but al- though they usually induce a strong antibody response, the cellular immune responses are ...a protein ... See full document
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Research advances in microneme protein 3 of Toxoplasma gondii
... T. gondii belongs to strictly intracellular parasitic protozoa. In induced immune responses in the body, cellular immun- ity is more important than humoral immunity; especially in the acute ... See full document
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Immunogenicity of Multi-epitope Vaccine Candidate against Toxoplasma gondii Infection in BALB/c Mice
... For vaccines to be effective against T. gondii they should induce protective cellular and humoral responses ...efficient immune response against the ...USM.TOXO1 antigen. The ... See full document
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Immune Responses Induced by pVAX/TgERK7 against Toxoplasma gondii Infection in BALB/c Mice
... Mitogen-activated protein (MAP) kinases expressed in all the eukaryotes constitute a family of proline-directed serine/threonine kinases, and play important roles in the regula- tion of cell proliferation, ... See full document
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DNA prime and peptide boost immunization protocol encoding the Toxoplasma gondii GRA4 induces strong protective immunity in BALB/c mice
... All mice were maintained in specific pathogen-free conditions, and all efforts were made to minimize suffer- ...in mice were used via euthanasia. Mice were monitored daily for signs of toxoplasmosis, ... See full document
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Immunization with a DNA vaccine encoding Toxoplasma gondii Superoxide dismutase (TgSOD) induces partial immune protection against acute toxoplasmosis in BALB/c mice
... the protective efficacy of DNA vaccine was evaluated against T. gondii RH (type I) ...to mice, whereas Type II strain is the predominant lineage causing toxoplasmosis in humans ...chose ... See full document
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Immune response and protective effect against chronic Toxoplasma gondii infection induced by vaccination with a DNA vaccine encoding profilin
... Zhang 1* † , Fu-Kai Zhang 1 , Meng Wang 1 , Ling-Ying Hu 1,3 and Xing-Quan Zhu 1,4 Abstract Background: Toxoplasma gondii is an obligate intracellular parasite that can infect almost ... See full document
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