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[PDF] Top 20 Evolutionary variation of papillomavirus E2 protein and E2 binding sites

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Evolutionary variation of papillomavirus E2 protein and E2 binding sites

Evolutionary variation of papillomavirus E2 protein and E2 binding sites

... DNA binding sites between papilloma- virus ...between papillomavirus genera E2 pro- teins, since a particular feature of BPV1 E2 protein may function differently or even be ... See full document

12

The Mitotic Chromosome Binding Activity of the Papillomavirus E2 Protein Correlates with Interaction with the Cellular Chromosomal Protein, Brd4

The Mitotic Chromosome Binding Activity of the Papillomavirus E2 Protein Correlates with Interaction with the Cellular Chromosomal Protein, Brd4

... mutated E2 pro- teins shows a general correlation with mitotic chromosome ...of E2. To assess the transcriptional activity of the series of E2 proteins and to determine whether this function ... See full document

13

Proteasomal Degradation of the Papillomavirus E2 Protein Is Inhibited by Overexpression of Bromodomain-Containing Protein 4

Proteasomal Degradation of the Papillomavirus E2 Protein Is Inhibited by Overexpression of Bromodomain-Containing Protein 4

... of E2 primarily by directly binding to ...Brd4 protein that lacks the E2-binding domain, which we refer to as Brd4-N (aa 1 to ...HPV31 E2 of a reporter gene under the control of ... See full document

13

NRIP, a Novel Calmodulin Binding Protein, Activates Calcineurin To Dephosphorylate Human Papillomavirus E2 Protein

NRIP, a Novel Calmodulin Binding Protein, Activates Calcineurin To Dephosphorylate Human Papillomavirus E2 Protein

... increased E2-driven transcription ac- tivity to ...the E2 transcription complex and cooperates with p300 in E2-mediated ...enhances E2 activity to the HPV-16 long control region (LCR832). Four ... See full document

14

Suppression of cellular proliferation by the papillomavirus E2 protein.

Suppression of cellular proliferation by the papillomavirus E2 protein.

... the E2 proteins have been extensively char- acterized for BPV-1. The BPV-1 E2 ORF encodes three dif- ferent proteins: an internally initiated E2 transcriptional re- pressor (E2-TR), a spliced ... See full document

9

Distinct Roles of Two Binding Sites for the Bovine Papillomavirus (BPV) E2 Transactivator on BPV DNA Replication

Distinct Roles of Two Binding Sites for the Bovine Papillomavirus (BPV) E2 Transactivator on BPV DNA Replication

... two binding sites for E2 termed BS11 and BS12, adjacent to the AT-rich and dyad elements, ...of E2 forms a relatively slowly migrating complex (C2 in the terminology of reference 23), using ... See full document

10

Characterization of the Functional Activities of the Bovine Papillomavirus Type 1 E2 Protein Single-Chain Heterodimers

Characterization of the Functional Activities of the Bovine Papillomavirus Type 1 E2 Protein Single-Chain Heterodimers

... Three E2 proteins encoded by the BPV1 genome are able to form homo- and heterodimers through their common DBD (10, 19), resulting in the formation of the mixture of E2 homo- and heterodimers, which are all ... See full document

8

Differential Requirements for Conserved E2 Binding Sites in the Life Cycle of Oncogenic Human Papillomavirus Type 31

Differential Requirements for Conserved E2 Binding Sites in the Life Cycle of Oncogenic Human Papillomavirus Type 31

... by E2 through these binding ...of E2 in partitioning of BPV1 origin plasmids has been described by Piirsoo and co- workers, who demonstrated a requirement for at least seven E2BS for stable ... See full document

7

Dynamic Localization of the Human Papillomavirus Type 11 Origin Binding Protein E2 through Mitosis While in Association with the Spindle Apparatus

Dynamic Localization of the Human Papillomavirus Type 11 Origin Binding Protein E2 through Mitosis While in Association with the Spindle Apparatus

... appropriate E2 fragments and placed in frame into the BglII and EcoRI sites of the pEGFP-C1 plasmid (Clontech, Mountain View, ...HPV-11 E2, replacing the corresponding sequence of BPV-1 ...BPV-1 ... See full document

9

Human TATA Binding Protein Inhibits Human Papillomavirus Type 11 DNA Replication by Antagonizing E1-E2 Protein Complex Formation on the Viral Origin of Replication

Human TATA Binding Protein Inhibits Human Papillomavirus Type 11 DNA Replication by Antagonizing E1-E2 Protein Complex Formation on the Viral Origin of Replication

... with E2, and titration onto the former oligonucleotide was saturable while titration onto the latter was not ...one E2 site and suggests that variation of DNA structure surrounding the E2 ... See full document

10

Cooperative Activation of Human Papillomavirus Type 8 Gene Expression by the E2 Protein and the Cellular Coactivator p300

Cooperative Activation of Human Papillomavirus Type 8 Gene Expression by the E2 Protein and the Cellular Coactivator p300

... factors binding to the enhancer may contribute with critical interactions with basal factors (32; reviewed in reference ...8 E2⌬N to cooperate may be due to the lack of domains essential for activation ... See full document

12

Brd4 Regulation of Papillomavirus Protein E2 Stability

Brd4 Regulation of Papillomavirus Protein E2 Stability

... PV E2 protein has several roles in the viral life cycle ...helicase, E2 initiates origin-specific viral DNA ...mitosis, E2 is also required for viral genome maintenance. In addition, E2 ... See full document

10

Phosphorylation of a Conserved Tyrosine in the Papillomavirus E2 Protein Regulates Brd4 Binding and Viral Replication

Phosphorylation of a Conserved Tyrosine in the Papillomavirus E2 Protein Regulates Brd4 Binding and Viral Replication

... pSG5-HA-HPV-31 E2 (58), codon-optimized pCDNA3-FLAG-HPV-31 E2, pCDNA-FGFR3 K650E ...pSG5-HA-HPV-31 E2 and the pDCDNA3-FLAG-HPV-31 E2 constructs using the Quick-Change XL Lightning kit (Agilent ... See full document

13

Binding of the E1 and E2 proteins to the origin of replication of bovine papillomavirus.

Binding of the E1 and E2 proteins to the origin of replication of bovine papillomavirus.

... the E2 recognition sequence. The interference over the E2 binding site was virtually identical to that produced by E2 alone, and we therefore concluded that these interferences corresponded to ... See full document

10

Phosphorylation Regulates Binding of the Human Papillomavirus Type 8 E2 Protein to Host Chromosomes

Phosphorylation Regulates Binding of the Human Papillomavirus Type 8 E2 Protein to Host Chromosomes

... between E2 phosphorylation, pro- tein half-life, and chromatin ...HPV8 E2 enhances both chromatin binding and protein ...whether E2 phosphorylation directly reg- ulates protein ... See full document

12

CK2 Phosphorylation Inactivates DNA Binding by the Papillomavirus E1 and E2 Proteins

CK2 Phosphorylation Inactivates DNA Binding by the Papillomavirus E1 and E2 Proteins

... phosphorylation sites in E1 and E2 on DNA replication and morphological ...and E2 proteins could be altered by CK2 phosphory- ...in E2 showed a greatly increased level of replication compared ... See full document

12

Identification and Analysis of Papillomavirus E2 Protein Binding Sites in the Human Genome

Identification and Analysis of Papillomavirus E2 Protein Binding Sites in the Human Genome

... the binding of the HPV11 E2 protein to cellular E2BSs and its ability to discriminate between viral and cellular E2BSs in the context of ...HPV11 E2 protein binds sequence specifically ... See full document

10

Different mechanisms contribute to the E2-mediated transcriptional repression of human papillomavirus type 18 viral oncogenes.

Different mechanisms contribute to the E2-mediated transcriptional repression of human papillomavirus type 18 viral oncogenes.

... full-length E2 protein repressed transcrip- tion less efficiently than a truncated protein lacking the entire transactivation domain, and since there was no evidence for recruitment of transcription ... See full document

7

Glaser, Laura Viola
  

(2017):


	Target gene regulation by EBV latent transcription factors - exploiting cellular enhancer elements.


Dissertation, LMU München: Fakultät für Biologie

Glaser, Laura Viola (2017): Target gene regulation by EBV latent transcription factors - exploiting cellular enhancer elements. Dissertation, LMU München: Fakultät für Biologie

... a protein could not be confirmed to date but gives rise to BART ncRNAs and BART ...of protein expression from several splicing variants, a role in viral or host gene regulation seems ...of E2 or E3 ... See full document

166

Hepatitis C virus E2 protein encapsulation into poly D, L-lactic-<em>co</em>-glycolide microspheres could induce mice cytotoxic T-cell response

Hepatitis C virus E2 protein encapsulation into poly D, L-lactic-<em>co</em>-glycolide&nbsp;microspheres could induce mice cytotoxic T-cell response

... carcinoma. E2 envelope glycoprotein of HCV type (HCV-E2) has been reported to bind human host cells and is a major target for developing anti-HCV ...recombinant protein, a truncated form of peptide, ... See full document

10

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