[PDF] Top 20 Expression of EBNA-1 mRNA Is Regulated by Cell Cycle during Epstein-Barr Virus Type I Latency
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Expression of EBNA-1 mRNA Is Regulated by Cell Cycle during Epstein-Barr Virus Type I Latency
... the cell cycle through the two E2F sites which lie within the Q ...the cell cycle-regulated expression of EBNA-1 mRNA during type I ... See full document
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Epstein-Barr Virus EBNA-3C Is Targeted to and Regulates Expression from the Bidirectional LMP-1/2B Promoter
... after EBNA-3C expression, suggesting that this is a specific effect of EBNA-3C and demonstrating that this occurred not only in growth-arrested cells, as previ- ously described, but also in ... See full document
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The Epstein-Barr virus EBNA-1 promoter Qp requires an initiator-like element.
... of cell types (15, 35) suggests that it is constitutively active, much as a housekeeping gene would be, in the absence of its only known negative regulator, ...of expression to ensure that sufficient ... See full document
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Autorepression of Epstein-Barr Virus Nuclear Antigen 1 Expression by Inhibition of Pre-mRNA Processing
... that EBNA-1 posttranscriptionally regulates expression from its promoter Qp by inhibiting pre-mRNA pro- ...Qp during latency III, as well as the Wp-restricted program in variant ... See full document
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A Single Amino Acid in EBNA-2 Determines Superior B Lymphoblastoid Cell Line Growth Maintenance by Epstein-Barr Virus Type 1 EBNA-2
... the EBNA-2 re- sponse elements of genes that are more strongly induced by type 1 EBNA-2 than type 2 EBNA-2, we used MEME-ChIP to perform unbiased motif searching on EBNA-2 ... See full document
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Restricted TET2 Expression in Germinal Center Type B Cells Promotes Stringent Epstein-Barr Virus Latency
... Mutu I and Mutu III were treated with acyclovir (100 g/ml) for 4 days, and DNA was isolated using the GenElute mammalian genomic DNA miniprep kit (Sigma) according to the manufacturer’s ...controls: 1 l ... See full document
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trans-Repression of Protein Expression Dependent on the Epstein-Barr Virus Promoter Wp during Latency
... BL-derived cell lines that maintain a variant program of EBV latency gene expression known as Wp-restricted latency, during which Wp remains transcription- ally active and Cp is silent ... See full document
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Regulation of Epstein-Barr Virus Latency Type by the Chromatin Boundary Factor CTCF
... Epstein Barr virus (EBV) can establish distinct latency types with different growth-transforming ...properties. Type I latency and type III latency can be ... See full document
10
Cell Cycle Association of the Retinoblastoma Protein Rb and the Histone Demethylase LSD1 with the Epstein-Barr Virus Latency Promoter Cp
... The Epstein-Barr virus C promoter (Cp) regulates the major multicistronic transcript encoding the EBNA- LP, 1, 2, and 3 genes required for B-cell proliferation during ... See full document
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Epstein-Barr Virus LF2: an Antagonist to Type I Interferon
... protein expression was determined by immunoblot analysis (data not ...inhibit type I IFN production, 293T cells were trans- fected with IRF7, IFN- ␣ 6 promoter-directed luciferase re- porter, and a ... See full document
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Mechanisms That Regulate Epstein-Barr Virus EBNA-1 Gene Transcription during Restricted Latency Are Conserved among Lymphocryptoviruses of Old World Primates
... Epstein-Barr virus (EBV), the only known human lymphocryptovirus (LCV), displays a remarkable degree of genetic and biologic identity to LCVs that infect Old World ...long-term latency within ... See full document
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Virus and Cell RNAs Expressed during Epstein-Barr Virus Replication
... infection, Epstein-Barr virus (EBV) rep- licates in the oropharyngeal epithelium (87) and then estab- lishes a latent infection in B lymphocytes, which are largely nonpermissive for virus ... See full document
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Human Monocytic Cell Lines Transformed In Vitro by Epstein-Barr Virus Display a Type II Latency and LMP-1-Dependent Proliferation
... Epstein-Barr virus (EBV) classically infects and transforms B lymphocytes in vitro, yielding lymphoblastoid cell lines ...monocytic cell line infected and transformed by EBV. This ... See full document
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Epstein-Barr Virus (EBV) Nuclear Protein 2-Induced Disruption of EBV Latency in the Burkitt’s Lymphoma Cell Line Akata: Analysis by Tetracycline-Regulated Expression
... EBNA2 expression on other latent EBV ...as expression of latent EBV genes charac- teristic to latency III were examined by the reverse transcrip- tion-PCR method as described previously ...by ... See full document
6
Epstein-Barr Virus Induces Global Changes in Cellular mRNA Isoform Usage That Are Important for the Maintenance of Latency
... expression in the ...0.5 cycle. (E) qRT-PCR depicting lysis-associated BMRF1 mRNA expression in the B-cell and LCL pairs and BL41 versus ...BMRF1 expression in the B95-8 ... See full document
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Identification of Major Phosphorylation Sites of Epstein-Barr Virus Nuclear Antigen Leader Protein (EBNA-LP): Ability of EBNA-LP To Induce Latent Membrane Protein 1 Cooperatively with EBNA-2 Is Regulated by Phosphorylation
... of EBNA-LP mutants containing multiple W repeat domains in which the mapped phosphorylation site in each W2 domain has a substitution of alanine or glutamic ...for EBNA-LP to express one of its biological ... See full document
10
Interferon-independent and -induced regulation of Epstein-Barr virus EBNA-1 gene transcription in Burkitt lymphoma.
... Epstein-Barr virus (EBV) establishes a latent infection of B lymphocytes that is sustained for the life of its human ...blastoid cell lines (LCLs). These are the six EBV-encoded nuclear ... See full document
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Latency Type-Dependent Modulation of Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Expression by Type I Interferons in B Cells
... the type I BL lines Akata (45), Rael (32), and Jijoye-M13 (27), the type III BL line Raji (28), and the cord blood-derived LCL CBM1-Ral-STO, transformed with the Rael EBV strain ...protein ... See full document
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Repression of Epstein-Barr Virus EBNA-1 Gene Transcription by pRb during Restricted Latency
... of EBNA-1 in the maintenance (if not replication) of the EBV genome dictates that EBNA-1 be expressed in a proliferating cell (3), why would there be a need to repress ... See full document
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EBNA-3B- and EBNA-3C-Regulated Cellular Genes in Epstein-Barr Virus-Immortalized Lymphoblastoid Cell Lines
... with virus derived from an EBNA-3B-deleted BAC mutant containing a kanamycin resistance cassette grow slowly and are hypomorphic for EBNA-3C ...the EBNA-3B ORF from an EBV genome cloned as a ... See full document
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