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[PDF] Top 20 Expression of the Epigenetic factor BORIS (CTCFL) in the Human Genome

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Expression of the Epigenetic factor BORIS (CTCFL) in the Human Genome

Expression of the Epigenetic factor BORIS (CTCFL) in the Human Genome

... Abstract BORIS, or CTCFL, the so called Brother of the Regulator of Imprinted Sites because of the extensive homology in the central DNA binding region of the protein to the related regulator, CTCF, is expressed ... See full document

11

Environmental Effects on Gene Expression Phenotype Have Regional Biases in the Human Genome

Environmental Effects on Gene Expression Phenotype Have Regional Biases in the Human Genome

... density, expression variations, and open chro- matin signature are plotted together for each chromo- some (supplemental Figure 1 at ...of expression variation should result from epigenetic, not ... See full document

7

Epigenetic histone modifications of human transposable elements: genome defense versus exaptation

Epigenetic histone modifications of human transposable elements: genome defense versus exaptation

... the human genome, some epigenetic modifi- cations of TEs may serve to regulate the expression of host genes rather than to silence the elements them- ...to expression differences should ... See full document

12

Mono-allelic retrotransposon insertion addresses epigenetic transcriptional repression in human genome

Mono-allelic retrotransposon insertion addresses epigenetic transcriptional repression in human genome

... the human gen- ome several million years ago and have many subfami- lies defined by distinct patterns of diagnostic base ...the human genome, hence the ongoing retrotranspositional insertions of the ... See full document

8

Genome wide assessment of imprinted expression in human cells

Genome wide assessment of imprinted expression in human cells

... comprehensive genome-wide search for imprint- ing and non-heritable allelic expression in human we found relatively few new imprinted genes, at least in LCLs and ...parent-of-origin expression ... See full document

14

Impact of cancer mutational signatures on transcription factor motifs in the human genome

Impact of cancer mutational signatures on transcription factor motifs in the human genome

... overall genome-wide excess of Ets-motif disruption, but a focal appearance of novel Ets-binding ...the expression of the corre- sponding gene (especially TERT and BCL2), highlighting the potential ... See full document

14

Transcription Factor Binding Dynamics and Spatial Co-localization In Human Genome

Transcription Factor Binding Dynamics and Spatial Co-localization In Human Genome

... gene expression in Drosophila ...gene expression in the 2/3 inter-stripe regions was enhanced by more than 10 ...gene expression level can be reasonably ...gene expression lev- els involving ... See full document

186

Epigenetic Repression of the NFATc1 Transcription Factor in Human Lymphomas

Epigenetic Repression of the NFATc1 Transcription Factor in Human Lymphomas

... nfatc1 expression and methylation pattern. Expression analysis demonstrated that L428 and KMH2 cells produce different amounts of all three NFATc1 protein isoforms whereas no NFATc1 was detected in L540 ... See full document

106

Genetic and Epigenetic Regulation of Human lincRNA Gene Expression

Genetic and Epigenetic Regulation of Human lincRNA Gene Expression

... >5%. Expression levels for all cell types and samples were measured with RNA-seq. Libraries were selected for polyadeny- lated transcripts and were sequenced as 49 bp paired-end reads in either HiSeq2000 or ... See full document

12

Epigenetic mechanisms and genome stability

Epigenetic mechanisms and genome stability

... Since expression of MMR components was unaltered, the consequences of DNMT1 deficiency appeared to be direct rather than an indirect consequence of genomic hypomethylation or global changes in gene activity (Guo ... See full document

16

CCCTC-Binding Factor Recruitment to the Early Region of the Human Papillomavirus 18 Genome Regulates Viral Oncogene Expression

CCCTC-Binding Factor Recruitment to the Early Region of the Human Papillomavirus 18 Genome Regulates Viral Oncogene Expression

... of human papillomavirus (HPV) gene expression is required for productive infec- ...CCCTC-binding factor (CTCF) functions in genome-wide chromatin organization and gene ...primary human ... See full document

16

Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair

Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair

... inducible factor-1α; HO-1, heme oxygenase-1; HuR, mRNA-binding protein in the 3′-untranslated region; JmjC, Jumonji C domain-containing histone demethylases; Keap1, kelch-like ECH-associated protein 1; MMP, matrix ... See full document

15

CCCTC binding factor recruitment to the early region of the human papillomavirus type 18 genome regulates viral oncogene expression

CCCTC binding factor recruitment to the early region of the human papillomavirus type 18 genome regulates viral oncogene expression

... of human papillomavirus (HPV) gene expression is required for productive infec- ...CCCTC-binding factor (CTCF) functions in genome-wide chromatin organization and gene ...primary human ... See full document

16

Original Article The expression of transcription factor BORIS and its association with the estrogen receptor beta (ER-β) in cervical carcinogenesis

Original Article The expression of transcription factor BORIS and its association with the estrogen receptor beta (ER-β) in cervical carcinogenesis

... I. BORIS in human cancers -- a ...VV. BORIS, a novel male germ-line-spe- cific protein associated with epigenetic repro- gramming events, shares the same 11-zinc- finger domain with CTCF, the ... See full document

14

Genome wide analysis of differential transcriptional and epigenetic variability across human immune cell types

Genome wide analysis of differential transcriptional and epigenetic variability across human immune cell types

... BLUEPRINT Human Variation Panel, enabling us to conduct the most comprehensive study of differential variability in primary cell types to ...gene expression and DNA methylation hyper- variability could be ... See full document

17

Epigenetic regulation of gene expression in osteoarthritis

Epigenetic regulation of gene expression in osteoarthritis

... transcription factor for chondrogenesis during the development of the skeletal system, in cooper- ation with SOX5 and ...SOX9 expression in ...SOX9 expression in advanced hip OA chondrocytes is ... See full document

7

Decline of FOXN1 gene expression in human thymus correlates with age: possible epigenetic regulation

Decline of FOXN1 gene expression in human thymus correlates with age: possible epigenetic regulation

... important factor of age related ...of human thymic senescence may lead to the discovery of novel therapeutic approaches aimed at the reestablishment of central and peripheral T cell ... See full document

14

The effect of epigenetic silencing and TP53 mutation on the expression of DLL4 in human cancer stem disorder

The effect of epigenetic silencing and TP53 mutation on the expression of DLL4 in human cancer stem disorder

... the expression of DLL4, the ChIP assay and the siRNA experiments in this study clearly show the presence of a binding site for TP53 on the DLL4 ...DLL4 expression is not ...binding factor and a key ... See full document

13

Genome-wide analysis of gene expression and alternative splicing in human medulloblastoma

Genome-wide analysis of gene expression and alternative splicing in human medulloblastoma

... in human medulloblastoma, such as isochromosome 17q and amplification of the MYC ...transgene expression, as monitored by flow cytometry analysis of EGFP- expressing ...the expression of the EGFP ... See full document

244

Epigenetic barriers to human gynogenesis

Epigenetic barriers to human gynogenesis

... balanced expression of imprinted genes and other imprinting regulatory factors between maternal and paternal epigenomes, it would be ideal to create a “paternal epigenetic ...other epigenetic ... See full document

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