[PDF] Top 20 Fibronectin binding protein B variation in Staphylococcus aureus
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Fibronectin binding protein B variation in Staphylococcus aureus
... and fibronectin (Calbiochem; 10 µg/ml) were placed at 4°C ...bound protein was detected by incubation with a 1:500 dilution of monoclonal antibody 7E8 that recognizes the N-terminal hexahistidine fusion ... See full document
37
Prevalence and distribution of adhesins and the expression of fibronectin binding protein (FnbA and FnbB) among Staphylococcus aureus isolates from Shahrekord Hospitals
... the fibronectin-binding proteins A and B were ...S. aureus specimens taken from the 10 wards of Hajar and Kashani Hospitals, the frequency of the clfA, clfB, fnbA, and fnbB genes was ...S. ... See full document
5
Staphylococcus aureus Protein A Mediates Interspecies Interactions at the Cell Surface of Pseudomonas aeruginosa
... pathogenesis. Staphylococcus aureus frequently coinfects with other pathogens in a range of different infectious ...S. aureus with Pseudomonas aerugi- nosa occurs commonly in people with cystic ... See full document
9
Staphylococcus aureus protein A binding to osteoblast tumour necrosis factor receptor 1 results in activation of nuclear factor kappa B and release of interleukin 6 in bone infection
... However Staphylococcus aureus infection is the most common, accounting for up to 80 % of clinical cases (Berendt & Byren, ...S. aureus and the recent identification of S. aureus isolates ... See full document
8
The Staphylococcus aureus “superbug”
... S. aureus strains that are multiply resis- tant to antibiotics — known as methicillin- resistant Staphylococcus aureus (MRSA) (3, 4) — although the acronym MRSA is somewhat misleading because the ... See full document
5
Adaptation in a Fibronectin Binding Autolysin of Staphylococcus saprophyticus
... in Staphylococcus aureus for polymorphisms in bacterial fibronectin-binding adhesins to affect the strength of binding and for these polymorphisms to associate with specific clinical phenotypes ... See full document
17
A novel Staphylococcus aureus biofilm phenotype mediated by the fibronectin binding proteins, FnBPA and FnBPB
... The MRSA strains in our local collection are from a re- stricted number of lineages (CC8 and CC22), and the evidence for FnBP-mediated biofilm in MRSA strains is limited to a number of clinical isolates that are amenable ... See full document
17
Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome
... ribosomal protein uL3, a ribosomal protein positioned at a location distant from that of the PTC, has been reported (15, ...linezolid binding (15, ... See full document
7
Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif
... Fg binding activities to that of peptide Efb-O in a competition ...the binding of the recombinant N-terminal segment of Efb (Efb-N) ...the binding of Efb-N and Coa-C to Fg, demonstrating that Coa-R0 ... See full document
10
Fibronectin binding proteins are required for biofilm formation by community associated methicillin resistant Staphylococcus aureus strain LAC
... S. aureus plasmid carrying the cat gene and served as a control to ensure that chloramphenicol acetyltransferase activity did not affect the ability of bac- teria to adhere to fibronectin or to form ...S. ... See full document
8
Identification of Key Determinants of Staphylococcus aureus Vaginal Colonization
... Fg binding contributed to vaginal persistence ...S. aureus interactions with extra- cellular matrix components, including Fg, in colonization and disease progression ...USA300 binding to Fg is ... See full document
19
Force Induced Strengthening of the Interaction between Staphylococcus aureus Clumping Factor B and Loricrin
... weakly binding folded state to a strongly binding extended ...bond protein is the mannose-binding adhesin FimH of Escherichia coli ...receptor binding site through two alternative ... See full document
14
Preclinical Efficacy of Clumping Factor A in Prevention of Staphylococcus aureus Infection
... of Staphylococcus aureus infections has become increasingly difficult because of the emergence of multidrug-resistant ...target protein for inclusion in a multivalent vaccine, we evaluated its ... See full document
13
The Ciliate Protist Tetrahymena pyriformis as a Cellular Adhesion Model for the Pathogenic Bacterium Staphylococcus aureus
... S. aureus has a large number of surface proteins called adhesins, belonging to the MSCRAMMs class (Microbial Surface Components Recognizing Adhesive Matrix Molecules) [7] [8] that enable specific adhesion to ... See full document
17
Multiplex Antibody Detection for Noninvasive Genus Level Diagnosis of Prosthetic Joint Infection
... three Staphylococcus species (S. aureus, ...IgG binding to the purified, recombinant forms of 16 proteins (see ...IgG binding was detected with R-phycoerythrin-conjugated goat anti- human ... See full document
9
Fibrinogen Activates the Capture of Human Plasminogen by Staphylococcal Fibronectin Binding Proteins
... Plg binding in staphylococcal pathogenesis, the molecular mechanism involved is still ...S. aureus to bind to and activate the nascent serum serine protease, which promotes destruction of opsonins, thus ... See full document
12
Human Immunoglobulin G Cannot Inhibit Fibrinogen Binding by the Genetically Diverse A Domain of Staphylococcus aureus Fibronectin-Binding Protein A
... (55). Protein-coated beads were then incubated with human serum which was diluted 1:100 in ...of variation larger than 25% and were excluded from further ... See full document
11
Fibronectin binding protein B (FnBPB) from Staphylococcus aureus protects against the antimicrobial activity of histones
... S. aureus LAC ⌬ fnbAfnbB mutant overexpressing FnBPB were immobilized on the surface of microtiter plates and then incubated with human ...experiments. B, to demonstrate the specificity of proteolysis, ... See full document
16
Subdomains N2N3 of Fibronectin Binding Protein A Mediate Staphylococcus aureus Biofilm Formation and Adherence to Fibrinogen Using Distinct Mechanisms
... The effect of zinc chelation on FnBP-mediated biofilm for- mation. Our previous work showed that Zn 2⫹ was required for SasG-mediated biofilm formation (12). The chelator diethylene- triaminepentaacetic acid (DTPA) also ... See full document
9
Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin binding adhesins fibronectin binding protein A and fibronectin binding protein B from Staphylococcus aureus
... ELISA binding assay in which the reactiv- ities of the FnBRs from FnBPA and FnBPB for intact Fn were ...low-affinity binding sites in the remaining ...Dose–response binding experiments in an ELISA ... See full document
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