[PDF] Top 20 Formulation and Evaluation of Gastroretentive Drug Delivery System of Zanamivir using Different Polymers

... Dept. of Pharmaceutics 50 JKKMMRF College of Pharmacy Ethylcellulose, dissolved in an organic solvent or solvent mixture, can be used on its own to produce water-insoluble films. Higher-viscosity ethylcellulose grades ... See full document

... novel drug delivery approach to control release of pharmacologically active ingredient as per patient ...Natural polymers like fenugreek mucilage are cheap, biodegradable and have been proved safe ... See full document

... of gastroretentive FDDS. The formulation code LFT6 having Methocel K15 showed superior results it may be constructive for prolonged drug release in the stomach to get better the bioavailability and ... See full document

... limited drug, whose solubility decreases with increase in the pH and has a short half life of 3-7 ...by using release rate controlling and gel forming polymers like HPMC, Xanthan gum,guar gum & ... See full document

... model drug. Released was studied in vivo from dried capsule from different environmental condition (distill water, pH 2 and 8) the effect of presence of increasing amount of drug in the ... See full document

... gastro-retentive drug delivery system i.e., floating drug delivery ...the formulation of floating tablets Xanthan gum, Gaur gum and in combination of Xanthan and Gaur gum were ... See full document

... the drug release. When drug release data fitted to Korsmeyer Peppas equation, the values of slope ‘n’ ...the drug release was by Non-Fickian ...tablet formulation studied, formulation ... See full document

... vitro drug release profiles obtained for tablets (F2) made with combinations of hydroxypropyl methylcellulose (HPMC) K4M, HPMC, and K100M showed lesser floating lag time (<60 seconds) and a prolonged floating ... See full document

... used polymers to develop these systems are polycarbonate, cellulose acetate, calcium alginate, Eudragit S, agar and low methoxylated pectin ...and drug release from dosage form are dependent on quantity of ... See full document

... controlled drug release. It has been observed that only hydrophilic polymers are not sufficient for floating characteristics and better results are possible with use of some soluble or gas-evolving ... See full document

... the drug release from dosage form in the physiological condition and kinetics of drug ...vitro drug release profiles of F1-F10 are shown in Figure ...controlled drug delivery. Baclofen ... See full document

... forming polymers such as polycarbonate, polyacrylate, polymethacrylate, and ...The formulation method includes a simple approach of thoroughly mixing the drug and the gel-forming ...unit ... See full document

... without drug and containing drug and other co polymers found that mean diameter increased as compared with beads without drug, even process parameters were kept constant the reason for ... See full document

... targeted drug delivery 5, 6 ...with different drug/polymer ratio of 1:1, 1:2 and 1:4 were prepared and the solid dispersions were obtained by hot melt extrusion ...plain drug 7, 8, 9 ... See full document

... oral delivery of ...various formulation components in the nanoparticle structure, and to determine interactions between alginate and chitosan, and between chitosan and dextran ... See full document

... of formulation and evaluation of pellets loaded with aceclofenac sodium (ACS) as model drug though pellitization technique by using the blend of Sodium alginate (SA) and glyceryl palmito ... See full document

... In-Vitro Release study Accurately weighted quantity of microsponges equivalent to 40 mg of Indomethacin were taken in muslin cloth and was kept in basket. During dissolution study, 10 ml aliquot was withdrawn at ... See full document

... Swelling refers to the uptake of water by a polymer system, with increase in volume. Swelling is often a prelude to polymer dissolution. However, swelling may occur without dissolution if water and the polymer are ... See full document

... controlled drug delivery. Muco/Bioadhesive drug carriers may prolong the residence time in the GI tract because they can adhere to mucus surface, resulting in an effective localized concentration ... See full document

... reliable formulation that has all the advantages of a single-unit form and also is devoid of any of the above mentioned disadvantages of single-unit ...many polymers have been used such as albumin, gelatin, ... See full document