[PDF] Top 20 Function of the Small Hydrophobic Protein of J Paramyxovirus
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Function of the Small Hydrophobic Protein of J Paramyxovirus
... the paramyxovirus family, it is conceiv- able that there is a greater capacity for the JPV genome to express larger foreign ...SH protein inhibits TNF- ␣ -induced NF-B ... See full document
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Role of Small Hydrophobic Protein of J Paramyxovirus in Virulence
... ABSTRACT J paramyxovirus (JPV) was first isolated from moribund mice with hemor- rhagic lung lesions in Australia in ...a paramyxovirus classified under the newly proposed genus ...The small ... See full document
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Function of the Respiratory Syncytial Virus Small Hydrophobic Protein
... prototype paramyxovirus parainfluenza virus 5 (PIV5; formerly known as simian virus 5), is a member of the Paramyxoviridae fam- ily, which includes important human and animal ...encode small ... See full document
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Genetic analysis of a hydrophobic domain of coxsackie B3 virus protein 2B: a moderate degree of hydrophobicity is required for a cis-acting function in viral RNA synthesis.
... Enterovirus protein 2B is a small hydrophobic protein that is localized at the outer surfaces of the virus-induced membrane vesicles on which vRNA synthesis takes ...of protein 2B with ... See full document
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Human Metapneumovirus Small Hydrophobic Protein Inhibits NF-κB Transcriptional Activity
... SH protein modulates NF- B posttranslational ...of protein from uninfected and infected cells were analyzed by Western blotting using either an anti-p65 or anti-p50 ...SH protein or its control ... See full document
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The Human Metapneumovirus Small Hydrophobic Protein Has Properties Consistent with Those of a Viroporin and Can Modulate Viral Fusogenic Activity
... encode small proteins capable of altering membrane permeability, or viroporins ...SH protein from RSV, a closely related virus, may function as a viroporin, and our results suggest important ... See full document
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The L Gene of J Paramyxovirus Plays a Critical Role in Viral Pathogenesis
... (L) protein. The L protein, with ⬎2,000 amino acid residues in a single polypeptide chain, is thought to be responsible for the enzymatic activities involved in viral RNA replication and ...(pigeon ... See full document
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Induction of Apoptosis by Paramyxovirus Simian Virus 5 Lacking a Small Hydrophobic Gene
... SH protein of SV5 is required to block TNF-␣ induced ...membrane protein residing in the endoplasmic reticulum, is a potent inhibitor of protein translocation from endoplasmic reticulum to Golgi, and ... See full document
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Function of Small Hydrophobic Proteins of Paramyxovirus
... the paramyxovirus family, causes acute infections in ...a small hydrophobic (SH) gene, which encodes a type I membrane protein of 57 amino acid ...The function of the SH protein ... See full document
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Characterization of the Tupaia Rhabdovirus Genome Reveals a Long Open Reading Frame Overlapping with P and a Novel Gene Encoding a Small Hydrophobic Protein
... Tupaias, or tree shrews, are small mammals widely distrib- uted in southeast Asia. Their taxonomical position has been controversially discussed for more than a hundred years, and after being classified as either ... See full document
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Vaccinia Virus Encodes I5, a Small Hydrophobic Virion Membrane Protein That Enhances Replication and Virulence in Mice
... its function was not predicted because of the absence of any recognizable functional motif or nonpoxvirus ...the protein was associated with the membranes of both immature and mature virions in viral ... See full document
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A small key unlocks a heavy door : the essential function of the small hydrophobic proteins SP B and SP C to trigger adsorption of pulmonary surfactant lamellar bodies
... one protein might still permit partial activity by the other protein, suggesting that the two proteins might not only act in an additive but even in a cooperative ... See full document
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Exceptional Flexibility in the Sequence Requirements for Coronavirus Small Envelope Protein Function
... E protein, the carboxy- terminal tail of E (amino acids 38 through 83) was connected to an amino- terminal hexahistidine tag in the vector pET-28a( ⫹ ) ...fusion protein was isolated by Ni-nitrilotriacetic ... See full document
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Identification and predicted sequence of a previously unrecognized small hydrophobic protein, SH, of the paramyxovirus simian virus 5.
... Lane 1, In vitro translation of total SV5-infected cell mRNA; lane 2, in vitro translation of mRNAs selected by pBR322 DNA; lane 3, in vitro translation of mRNAs selected by SH-specific [r] ... See full document
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Recognition of base J in duplex DNA by J-binding protein
... of J in the genome. In vivo, ⬃ 50% of the total J is in telomeres with the remaining J found in imperfect simple sequence repeats as follows: the minichromosomal 177-bp re- peats, the long array of ... See full document
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Membrane Permeabilization by Small Hydrophobic Nonstructural Proteins of Japanese Encephalitis Virus
... rather small polypeptides with a hydrophobic stretch of amino acids capable of forming an amphipathic helix; therefore, they possess activities like some ionophores or membrane-active toxins (reviewed in ... See full document
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Simulatting interaction of tuberculosis antigen 85B protein with hydrophobic surface graphene
... 6 There are more than twenty drugs available for TB treatment, and they are used in differing combinations in different circumstances, such as for the treatment of new patients where there is no suggestion of any drug ... See full document
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Altered Function in CD8+ T Cells following Paramyxovirus Infection of the Respiratory Tract
... Our laboratory is interested in elucidating the factors that control the elicitation and maintenance of high- versus low- avidity cells following infection of the respiratory tract. We have used simian virus 5 (SV5) as a ... See full document
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Paramyxovirus persistence
... However, the fmding that BF cells do release interferon following virus infection and that exogenous interferon is able to restrict virus protein synthesis in BF cells suggests that inte[r] ... See full document
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The Paramyxovirus Simian Virus 5 V Protein Slows Progression of the Cell Cycle
... V protein is incorporated into virions (⬃350 mol- ecules per virion), and it is found associated with the nucleo- capsid ...V protein does not appear to be incorporated into ...V protein has been ... See full document
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