[PDF] Top 20 Gene-Environment Interaction in Chronic Disease
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Gene-Environment Interaction in Chronic Disease
... The role of the microbiota is not restricted to early childhood. Although initial colonisation of niches like the gut and, possibly, the airways is likely to have a determining effect on the profile of the adult ... See full document
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Gene-environment interactions and obesity: recent developments and future directions
... and environment factors in the development of ...examining gene and dietary intervention interactions for weight loss and main- tenance [8,23,24,41], but there are still many ...understand disease ... See full document
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ASSOCIATION AND GENE-ENVIRONMENT INTERACTION EFFECT OF VEGFR-2 GENE POLYMORPHISM WITH MENTAL HEALTH ON METABOLIC RISK FACTORS OF CARDIOVASCULAR DISEASE IN CHINESE MALAYSIAN FEMALE ADULTS
... (VEGFR-2) gene rs2071559 polymorphism were reported in Asian ...and interaction effects of VEGFR-2 gene rs2071559 polymorphism with mental health on metabolic risk factors of CVD in Chinese Malaysian ... See full document
5
Extraction of Gene Environment Interaction from the Biomedical Literature
... same environment terms (serious obstetric com- ...identify environment terms due to many negative ...with environment as a negative example, as shown in the first column of Table ...correct ... See full document
10
Gene-Environment Interactions and Airway Disease in Children
... airway disease in children, inheritance alone does not account for the incidence and prevalence of this ...the interaction of multiple genes, coupled with environmen- tal ...this disease in ...of ... See full document
11
Vascular Endothelial Growth Factor (VEGF) Gene Promoter Polymorphisms and Disease Progression in North Indian Cohort with Autosomal Dominant Polycystic Kidney Disease
... from Chronic Kidney Disease (CKD) Registry of India reveals that ADPKD accounts for ...the disease, the age of onset of end stage renal disease (ESRD) and the extra-renal manifestations vary ... See full document
10
Chronic disease in a digital health environment
... Communication is the next battleground, and here we have two main models: peer to peer and one to many. Peer to peer is what we best know now as e-mail, but increasingly other modes of one-on-one communication are being ... See full document
6
Gene environment interaction impacts on heart development and embryo survival
... heart disease (CHD) is the most common type of birth ...the interaction between Nkx2-5 and short-term gestational hypoxia, which suggest that reduced Nkx2-5 expression and a prolonged hypoxia-inducible ... See full document
13
ADAM33 gene polymorphisms in chronic obstructive pulmonary disease
... rising interest in the clarification of the pathogenic mechanisms underlying this common disease, in order to deduce appropriate and effective therapeutic inter- ventions. Environmental and genetic determinants ... See full document
5
Selection of genes for gene-environment interaction studies: a candidate pathway-based strategy using asthma as an example
... for interaction with tobacco on ...the gene selection, we expect that the strategy proposed here will improve the ability to identify the joint effects and interactions of environmental and genetic fac- ... See full document
5
Genetic association analysis of coronary heart disease by profiling gene environment interaction based on latent components in longitudinal endophenotypes
... To study effects of potential interactions between SNPs and so-derived TICs, we carried out logistic regression of CHD status on SNP genotypes and an interaction term for SNP × TIC, using two types of models: ones ... See full document
5
Gene-Environment Interaction in Type II Diabetes
... is gene-environment ...the interaction between genetic and environment ...that interaction between the genetic and environment factors have been significantly associated with ... See full document
5
Developing a synthetic psychosocial stress measure and harmonizing CVD risk data: a way forward to GxE meta and mega analyses
... cardiovascular disease; GxE: gene-by-environment interaction; SNP: sin- gle nucleotide polymorphism; EBF1: early B-cell factor 1; BDNF: brain-derived neurotrophic factor; 5HTR2C: ... See full document
8
Effects of genetic and environmental factors and gene environment interaction on expression variations of genes related to stroke in rat brain
... In addition, since dietary factors play an important role in the onset of stroke in rat [25-28], to investigate if dietary factors regulate significantly the expressions of genes may be helpful for understanding stroke ... See full document
27
Role of microRNA in chronic lymphocytic leukemia onset and progression
... modulate gene expression is essential to provide fine control on several cell processes and its deficiency can be involved in CLL development/ ...or interaction with other ... See full document
6
Complex two gene modulation of lung disease severity in children with cystic fibrosis
... through the complement pathway, it is also a potent regulator of inflammatory pathways (9), which are highly dependent on the concentration of circulating MBL2. Low plasma MBL2 levels induce monocyte production of ... See full document
11
Clinical relevancy and determinants of potential drug–drug interactions in chronic kidney disease patients: results from a retrospective analysis
... The majority of the pDDIs identified in this study are of moderate and minor severity. A few interactions with serious and contraindicated severity have also been observed, which have considerable potential to ... See full document
7
Polymorphism of Renalase Gene in Patients of Chronic Kidney Disease
... renalase gene polymorphism? Who are the candidates who should undergo polymorphisms test- ing before development of nephropathy? Are there any clinical parameters and biomarkers that may predict the early ... See full document
8
Chronic obstructive lung disease and posttraumatic stress disorder: current perspectives
... lung disease states, 2) PTSD in the sample, and 3) an examina- tion of associations between COPD and PTSD reflecting at least one of the following main topical areas: epidemiology, treatment receipt, or outcomes ... See full document
15
Polymorphisms in pre-miRNA genes and cooking oil fume exposure as well as their interaction on the risk of lung cancer in a Chinese nonsmoking female population
... an interaction between miRNA SNPs and exposure to cooking oil fumes, and hence, the statistically significant tests were explored to assess the interaction on both additive scale and multiplicative ...the ... See full document
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