[PDF] Top 20 The effect of glutamine therapy on outcomes in critically ill patients: a meta analysis of randomized controlled trials

... of glutamine to ICU patients re- duces mortality and the incidence of new ...small trials, many of which were of poor quality. Recently, two large trials [14,15] reported the administration of ... See full document

... beneficial effect on certain surrogate end- points, it failed to reduce mortality and was associated with an excessive risk of adverse events, such as hyperkalemia, hypotension, and renal ...aliskiren ... See full document

... two meta-analyses of the initial randomized controlled trials of enteral GLN supplementation, García-de-Lorenzo et ...first meta-analysis the number of studies that included ... See full document

... our meta-analysis are the comprehen- sive and most up-to-date search of the worldwide litera- ture without restriction to only English-written articles, the inclusion of data from the largest and most ... See full document

... patient outcomes, including day-28 mortality, length of ICU stay, length of hospital stay, and duration of mechanical ...better effect on day-28 mortality of surgical patients, and has lower ... See full document

... Previous meta-analyses evaluating this topic have been ...published meta-analyses. First, this meta-analysis included an add- itional eight trials performed since ...Chinese ... See full document

... [32]. There is no consensus on the definition of “early”. The term ‘early’ was defined as EN administration within postoperative day 3 [33]; however, ‘early’ has been more recently rede- fined as EN administration within ... See full document

... patient-important outcomes and in particu- lar the impressive scarcity of outcomes assessed after ICU discharge are ...critical ill- ness, growth hormone improved nitrogen balance but has been also ... See full document

... This meta-analysis has several ...non-cardiac critically ill patients, and some included RCTs were small sample and sin- gle ...of critically ill patients (35). ... See full document

... For systematic reviews of Wenxin keli in the treatment of cardiovascular disease, we used the indicators of angina pectoris total efficiency, ECG total efficiency, and adverse outcomes for comparison with the ... See full document

... clinical outcomes, and status of illness (unstable angina pectoris, STEMI, ...primary outcomes were all- cause mortality and MI at 30 ...of trials was assessed with the components recommended by the ... See full document

... large-scale randomized controlled trials (RCTs), non-standardized triggers for RRT initiation, and heterogeneities of population and study ...clinical trials were unable to replicate these ... See full document

... in critically ill ARF ...prospective randomized controlled trials (RCTs) have directly compared the different ap- proaches ...whole, meta-analysis of available data did ... See full document

... sequential analysis (TSA) for the pri- mary and secondary outcomes to assess this risk using TSA program version ...co-primary outcomes and 2.5% for the co- secondary outcomes, a beta (power) ... See full document

... a meta-analysis of randomized, double-blind, placebo-controlled clinical trials to separately assess the effect of continuous ultrasound (US) therapy and pulsed ultrasound ... See full document

... insulin therapy on mortality in surgical and medical ...surgical patients and (B) all medical patients was not statistically signifi cant (P = ...surgical patients only within the same – that ... See full document

... Clinical Trials Registry Platform. We will use a validated randomized control trial search filter to identify studies evaluating any strategy to optimize sedation in mechanically ventilated adult ...Our ... See full document

... This meta-analysis was performed to evaluate the efficacy and safety of saxagliptin and met- formin as initial combination therapy in patients with type 2 ...A meta-analysis was ... See full document

... design, randomized controlled trials; (b) population, adult (>18 years old) critically ill patients in the ICU; (c) intervention, comparison between daily bathing with ... See full document

... surprisingly critically ill patients most often exhibit a larger scatter in various parameters as compared to healthy ...of patients if two different groups should be compared for a parameter ... See full document