[PDF] Top 20 Higher-Order Structure of the Rous Sarcoma Virus SP Assembly Domain
Has 10000 "Higher-Order Structure of the Rous Sarcoma Virus SP Assembly Domain" found on our website. Below are the top 20 most common "Higher-Order Structure of the Rous Sarcoma Virus SP Assembly Domain".
Higher-Order Structure of the Rous Sarcoma Virus SP Assembly Domain
... the SP assembly (SPA) domain, and we propose that neighboring SPA units in a Gag hexamer co- alesce to form a six-helix ...vitro assembly, alanine scanning mutagenesis, and biophysical ... See full document
13
Fine mapping and characterization of the Rous sarcoma virus Pr76gag late assembly domain.
... The assembly domain in RSV p2 maps to the conserved PPPPYV ...of virus particles from cells or on processing of the CA, as seen by the appearance of the triplet bands ... See full document
6
An assembly domain of the Rous sarcoma virus Gag protein required late in budding.
... AD2 mutants lacking the p2b sequence were completely defective for particle release even though their Gag proteins were tightly associated with the membrane fraction and exhibited high l[r] ... See full document
14
The Structure of Immature Virus-Like Rous Sarcoma Virus Gag Particles Reveals a Structural Role for the p10 Domain in Assembly
... immature virus particles, requiring interactions between Gag proteins that form a protein layer under the viral ...the virus into its infectious ...in order to understand how virus ... See full document
9
Mutational analysis of the oligomer assembly domain in the transmembrane subunit of the Rous sarcoma virus glycoprotein.
... form higher-molecular-weight complexes despite the absence of this second potential ...driving assembly of wild- type Env oligomers but may instead resemble those responsi- ble for an oligomeric form found ... See full document
7
PR Domain of Rous Sarcoma Virus Gag Causes an Assembly/Budding Defect in Insect Cells
... A further conclusion is that baculovirus-produced ⌬PR par- ticles viewed by thin-section TEM are 10 to 15 nm smaller in average diameter than infectious RSV particles collected from avian cells. Although this difference ... See full document
6
The membrane-binding domain of the Rous sarcoma virus Gag protein.
... of Rous sarcoma virus (RSV) can direct particle assembly and budding at the plasma membrane independently of the other virus-encoded ...membrane-binding domain that is absolutely ... See full document
5
Membrane Binding of the Rous Sarcoma Virus Gag Protein Is Cooperative and Dependent on the Spacer Peptide Assembly Domain
... and assembly of retroviral Gag proteins into a lattice are ...purified Rous sarcoma virus Gag and Gag truncations, we studied the interrelation of Gag-Gag interaction and Gag-membrane ... See full document
13
Lysines Close to the Rous Sarcoma Virus Late Domain Critical for Budding
... leukemia virus type 1, which does not bud well compared to RSV and lacks lysines close to its L domain, was found to be released at a higher level upon introduction of lysines near its L ... See full document
11
In Vivo Interference of Rous Sarcoma Virus Budding by cis Expression of a WW Domain
... nascent virus particles separate or “pinch off” from the cell surface is largely ...the virus release step is directed by the late (L) assembly domain within ...L domain of Rous ... See full document
7
Viral DNA Synthesis Defects in Assembly-Competent Rous Sarcoma Virus CA Mutants
... the structure of the Gag precursor and the mature CA protein does not appear sufficient to explain its unusually strong ...Gag assembly to the final formation of an active core might be consistent with the ... See full document
9
Importance of the N Terminus of Rous Sarcoma Virus Protease for Structure and Enzymatic Function
... of Rous sarcoma virus (RSV) PR are exquisitely sensitive to mutations at the N ...At higher concentrations, dimerization was observed, but the dimer lacked or was deficient in enzymatic ... See full document
10
In vitro assembly of virus-like particles with Rous sarcoma virus Gag deletion mutants: identification of the p10 domain as a morphological determinant in the formation of spherical particles.
... prevents assembly until Gag reaches the plasma ...different assembly pathway than the former, studies of Gag mutants suggest that the ob- served differences may well be ...MA domain of M-PMV Gag ... See full document
11
Nucleic Acid Binding-Induced Gag Dimerization in the Assembly of Rous Sarcoma Virus Particles In Vitro
... efficient assembly is 16 nucleotides (nt), twice the protein’s binding site ...in assembly is to promote the formation of Gag dimers. In order to gain further insight into the role of dimerization, ... See full document
9
Contributions of Charged Residues in Structurally Dynamic Capsid Surface Loops to Rous Sarcoma Virus Assembly
... the higher-order interactions that build the im- mature ...Gag assembly capacity despite mutations in prominent CA-CA inter- faces suggests that Gag lattice assembly can accommodate certain ... See full document
15
Effect of Multimerization on Membrane Association of Rous Sarcoma Virus and HIV-1 Matrix Domain Proteins
... budding virus particle at the PM. Prior to assembly, HIV-1 Gag becomes complexed with cellular proteins, for example, ABCE1 (also called HP68) (85, 86) or AP3 (87), and RSV Gag may enter similar complexes ... See full document
11
An LYPSL Late Domain in the Gag Protein Contributes to the Efficient Release and Replication of Rous Sarcoma Virus
... the assembly and budding steps, while pulse-chase kinetics mea- sure the product of several steps, including not only assembly and budding but also Gag ...a virus particle is only 5 to 10 min, as ... See full document
12
Insertion of a Classical Nuclear Import Signal into the Matrix Domain of the Rous Sarcoma Virus Gag Protein Interferes with Virus Replication
... Budding efficiency of wild-type and nucleoplasmin NLS- containing viruses. Although the Gag.NLS protein did not appear to accumulate in the nucleus under steady-state condi- tions, a more dynamic assay might detect ... See full document
9
Overlapping Roles of the Rous Sarcoma Virus Gag p10 Domain in Nuclear Export and Virion Core Morphology
... capsid structure in many of the ...internal structure as seen by electron microscopy but also by the slow or incomplete processing of cleavage sites at the CA-SP junctions and the disordered vRNA ... See full document
11
Self-assembly in vitro of purified CA-NC proteins from Rous sarcoma virus and human immunodeficiency virus type 1.
... into virus-like particles when expressed in ...for Rous sarcoma virus (RSV) and for human immunodeficiency virus type 1 ...of assembly, and in this case all three proteins formed ... See full document
11
Related subjects